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Interaction of the Warsaw breakage syndrome DNA helicase DDX11 with the replication fork-protection factor Timeless promotes sister chromatid cohesion.

Cortone G, Zheng G, Pensieri P, Chiappetta V, Tatè R, Malacaria E, Pichierri P, Yu H, Pisani FM.

PLoS Genet. 2018 Oct 10;14(10):e1007622. doi: 10.1371/journal.pgen.1007622. eCollection 2018 Oct.


Breakage in Two Points of a Short and Undersized "Affixus" Cephalomedullary Nail in a Very Active Elderly Female: A Case Report and Review of the Literature.

Rollo G, Rinonapoli G, Pichierri P, Bisaccia M, Caraffa A, Meccariello L.

Case Rep Orthop. 2018 Sep 13;2018:9580190. doi: 10.1155/2018/9580190. eCollection 2018.


Effect of trochleocapitellar index on adult patient-reported outcomes after noncomminuted intra-articular distal humeral fractures.

Rollo G, Rotini R, Eygendaal D, Pichierri P, Bisaccia M, Prkic A, Stasi A, Meccariello L.

J Shoulder Elbow Surg. 2018 Jul;27(7):1326-1332. doi: 10.1016/j.jse.2018.02.073.


Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress.

Palma A, Pugliese GM, Murfuni I, Marabitti V, Malacaria E, Rinalducci S, Minoprio A, Sanchez M, Mazzei F, Zolla L, Franchitto A, Pichierri P.

Nucleic Acids Res. 2018 Jun 1;46(10):5109-5124. doi: 10.1093/nar/gky280.


The Waterfall Fascia Lata Interposition Arthroplasty "Grika Technique" as Treatment of Posttraumatic Osteoarthritis of the Elbow in a High-Demand Adult Patient: Validity and Reliability.

Rollo G, Rotini R, Eygendaal D, Pichierri P, Prkic A, Bisaccia M, Lanzetti RM, Lupariello D, Meccariello L.

Case Rep Orthop. 2018 Apr 22;2018:8253732. doi: 10.1155/2018/8253732. eCollection 2018.


TEN versus external fixator in the management of pediatric diaphyseal femoral fractures: evaluation of the outcomes.

Rollo G, Guida P, Bisaccia M, Pichierri P, Filipponi M, Lanzetti RM, Caraffa A, Stasi A, Russi V, Lupariello D, Meccariello L.

Eur J Orthop Surg Traumatol. 2018 Oct;28(7):1421-1428. doi: 10.1007/s00590-018-2201-3. Epub 2018 Apr 20.


The challenge of nonunion after osteosynthesis of the clavicle: is it a biomechanical or infection problem?

Rollo G, Pichierri P, Marsilio A, Filipponi M, Bisaccia M, Meccariello L.

Clin Cases Miner Bone Metab. 2017 Sep-Dec;14(3):372-378. doi: 10.11138/ccmbm/2017.14.3.372. Epub 2017 Dec 27.


Grafting and fixation of proximal humeral aseptic non union: a prospective case series.

Rollo G, Rotini R, Pichierri P, Giaracuni M, Stasi A, Macchiarola L, Bisaccia M, Meccariello L.

Clin Cases Miner Bone Metab. 2017 Sep-Dec;14(3):298-304. doi: 10.11138/ccmbm/2017.14.3.298. Epub 2017 Dec 27.


SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.

Malacaria E, Franchitto A, Pichierri P.

Sci Rep. 2017 Mar 14;7:44464. doi: 10.1038/srep44464.


The challenge of non-union in subtrochanteric fractures with breakage of intramedullary nail: evaluation of outcomes in surgery revision with angled blade plate and allograft bone strut.

Rollo G, Tartaglia N, Falzarano G, Pichierri P, Stasi A, Medici A, Meccariello L.

Eur J Trauma Emerg Surg. 2017 Dec;43(6):853-861. doi: 10.1007/s00068-016-0755-5. Epub 2017 Mar 3.


Way out/way in: How the relationship between WRN and CDK1 may change the fate of collapsed replication forks.

Palermo V, Rinalducci S, Sanchez M, Grillini F, Franchitto A, Pichierri P.

Mol Cell Oncol. 2016 Dec 9;4(1):e1268243. doi: 10.1080/23723556.2016.1268243. eCollection 2017.


WRNIP1: A new guardian of genome integrity at stalled replication forks.

Leuzzi G, Marabitti V, Pichierri P, Franchitto A.

Mol Cell Oncol. 2016 Aug 3;3(5):e1215777. eCollection 2016.


CDK1 phosphorylates WRN at collapsed replication forks.

Palermo V, Rinalducci S, Sanchez M, Grillini F, Sommers JA, Brosh RM Jr, Zolla L, Franchitto A, Pichierri P.

Nat Commun. 2016 Sep 16;7:12880. doi: 10.1038/ncomms12880.


Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells.

Hengel SR, Malacaria E, Folly da Silva Constantino L, Bain FE, Diaz A, Koch BG, Yu L, Wu M, Pichierri P, Spies MA, Spies M.

Elife. 2016 Jul 19;5. pii: e14740. doi: 10.7554/eLife.14740.


WRNIP1 protects stalled forks from degradation and promotes fork restart after replication stress.

Leuzzi G, Marabitti V, Pichierri P, Franchitto A.

EMBO J. 2016 Jul 1;35(13):1437-51. doi: 10.15252/embj.201593265. Epub 2016 May 30.


The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation.

Iannascoli C, Palermo V, Murfuni I, Franchitto A, Pichierri P.

Nucleic Acids Res. 2015 Nov 16;43(20):9788-803. doi: 10.1093/nar/gkv836. Epub 2015 Aug 14.


MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation.

Grasso F, Ruggieri V, De Luca G, Leopardi P, Mancuso MT, Casorelli I, Pichierri P, Karran P, Bignami M.

Oncotarget. 2015 Apr 10;6(10):7481-92.


Percutaneous hallux valgus surgery: strengths and weakness in our clinical experience.

Pichierri P, Sicchiero P, Fioruzzi A, Maniscalco P.

Acta Biomed. 2014 Nov 10;85 Suppl 2:121-5.


Checkpoint-dependent and independent roles of the Werner syndrome protein in preserving genome integrity in response to mild replication stress.

Basile G, Leuzzi G, Pichierri P, Franchitto A.

Nucleic Acids Res. 2014 Nov 10;42(20):12628-39. doi: 10.1093/nar/gku1022. Epub 2014 Oct 28.


Replication fork recovery and regulation of common fragile sites stability.

Franchitto A, Pichierri P.

Cell Mol Life Sci. 2014 Dec;71(23):4507-17. doi: 10.1007/s00018-014-1718-9. Epub 2014 Sep 13. Review.


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