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Items: 18


Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA.

Sutherland LC, Thibault P, Durand M, Lapointe E, Knee JM, Beauvais A, Kalatskaya I, Hunt SC, Loiselle JJ, Roy JG, Tessier SJ, Ybazeta G, Stein L, Kothary R, Klinck R, Chabot B.

BMC Mol Biol. 2017 Jul 20;18(1):19. doi: 10.1186/s12867-017-0096-x.


ISOWN: accurate somatic mutation identification in the absence of normal tissue controls.

Kalatskaya I, Trinh QM, Spears M, McPherson JD, Bartlett JMS, Stein L.

Genome Med. 2017 Jun 29;9(1):59. doi: 10.1186/s13073-017-0446-9.


Overview of major molecular alterations during progression from Barrett's esophagus to esophageal adenocarcinoma.

Kalatskaya I.

Ann N Y Acad Sci. 2016 Oct;1381(1):74-91. doi: 10.1111/nyas.13134. Epub 2016 Jul 14. Review.


Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer.

Braunstein M, Liao L, Lyttle N, Lobo N, Taylor KJ, Krzyzanowski PM, Kalatskaya I, Yao CQ, Stein LD, Boutros PC, Twelves CJ, Marcellus R, Bartlett JM, Spears M.

Breast Cancer Res. 2016 Feb 6;18(1):16. doi: 10.1186/s13058-016-0676-6.


Pathprinting: An integrative approach to understand the functional basis of disease.

Altschuler GM, Hofmann O, Kalatskaya I, Payne R, Ho Sui SJ, Saxena U, Krivtsov AV, Armstrong SA, Cai T, Stein L, Hide WA.

Genome Med. 2013 Jul 26;5(7):68. doi: 10.1186/gm472. eCollection 2013.


Interruption of the ionic lock in the bradykinin B2 receptor results in constitutive internalization and turns several antagonists into strong agonists.

Leschner J, Wennerberg G, Feierler J, Bermudez M, Welte B, Kalatskaya I, Wolber G, Faussner A.

J Pharmacol Exp Ther. 2013 Jan;344(1):85-95. doi: 10.1124/jpet.112.199190. Epub 2012 Oct 18.


Identification of differentially expressed proteins in direct expressed prostatic secretions of men with organ-confined versus extracapsular prostate cancer.

Kim Y, Ignatchenko V, Yao CQ, Kalatskaya I, Nyalwidhe JO, Lance RS, Gramolini AO, Troyer DA, Stein LD, Boutros PC, Medin JA, Semmes OJ, Drake RR, Kislinger T.

Mol Cell Proteomics. 2012 Dec;11(12):1870-84. doi: 10.1074/mcp.M112.017889. Epub 2012 Sep 17.


Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation.

Yu M, Lin G, Arshadi N, Kalatskaya I, Xue B, Haider S, Nguyen F, Boutros PC, Elson A, Muthuswamy LB, Tonks NK, Muthuswamy SK.

Mol Cell Biol. 2012 Oct;32(19):3913-24. doi: 10.1128/MCB.00068-12. Epub 2012 Jul 30.


Bile exposure inhibits expression of squamous differentiation genes in human esophageal epithelial cells.

Reveiller M, Ghatak S, Toia L, Kalatskaya I, Stein L, D'Souza M, Zhou Z, Bandla S, Gooding WE, Godfrey TE, Peters JH.

Ann Surg. 2012 Jun;255(6):1113-20. doi: 10.1097/SLA.0b013e3182512af9.


Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells.

Sprowl JA, Reed K, Armstrong SR, Lanner C, Guo B, Kalatskaya I, Stein L, Hembruff SL, Tam A, Parissenti AM.

Breast Cancer Res. 2012 Jan 6;14(1):R2.


Early G₁ cyclin-dependent kinases as prognostic markers and potential therapeutic targets in esophageal adenocarcinoma.

Ismail A, Bandla S, Reveiller M, Toia L, Zhou Z, Gooding WE, Kalatskaya I, Stein L, D'Souza M, Litle VR, Peters JH, Pennathur A, Luketich JD, Godfrey TE.

Clin Cancer Res. 2011 Jul 1;17(13):4513-22. doi: 10.1158/1078-0432.CCR-11-0244. Epub 2011 May 18.


Reactome: a database of reactions, pathways and biological processes.

Croft D, O'Kelly G, Wu G, Haw R, Gillespie M, Matthews L, Caudy M, Garapati P, Gopinath G, Jassal B, Jupe S, Kalatskaya I, Mahajan S, May B, Ndegwa N, Schmidt E, Shamovsky V, Yung C, Birney E, Hermjakob H, D'Eustachio P, Stein L.

Nucleic Acids Res. 2011 Jan;39(Database issue):D691-7. doi: 10.1093/nar/gkq1018. Epub 2010 Nov 9.


AMD3100 is a CXCR7 ligand with allosteric agonist properties.

Kalatskaya I, Berchiche YA, Gravel S, Limberg BJ, Rosenbaum JS, Heveker N.

Mol Pharmacol. 2009 May;75(5):1240-7. doi: 10.1124/mol.108.053389. Epub 2009 Mar 2.


C-terminal fusion of eGFP to the bradykinin B2 receptor strongly affects down-regulation but not receptor internalization or signaling.

Kalatskaya I, Schüssler S, Seidl C, Jochum M, Faussner A.

Biol Chem. 2006 May;387(5):603-10.


The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B(1) and B(2) bradykinin receptors.

Faussner A, Bauer A, Kalatskaya I, Schüssler S, Seidl C, Proud D, Jochum M.

FEBS J. 2005 Jan;272(1):129-40.


Mutation of tyrosine in the conserved NPXXY sequence leads to constitutive phosphorylation and internalization, but not signaling, of the human B2 bradykinin receptor.

Kalatskaya I, Schüssler S, Blaukat A, Müller-Esterl W, Jochum M, Proud D, Faussner A.

J Biol Chem. 2004 Jul 23;279(30):31268-76. Epub 2004 May 25.


Downregulation of bradykinin B2 receptor in human fibroblasts during prolonged agonist exposure.

Blaukat A, Micke P, Kalatskaya I, Faussner A, Müller-Esterl W.

Am J Physiol Heart Circ Physiol. 2003 Jun;284(6):H1909-16.


Expression levels strongly affect ligand-induced sequestration of B2 bradykinin receptors in transfected cells.

Faussner A, Bauer A, Kalatskaya I, Jochum M, Fritz H.

Am J Physiol Heart Circ Physiol. 2003 Jun;284(6):H1892-8.

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