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Items: 1 to 20 of 83

1.

Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan.

Hirose M, Schilf P, Zarse K, Busch H, Fuellen G, Jöhren O, Köhling R, König IR, Richer B, Rupp J, Schwaninger M, Seeger K, Sina C, Ristow M, Ibrahim SM.

Genes (Basel). 2019 Jul 13;10(7). pii: E532. doi: 10.3390/genes10070532.

2.

A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice.

Hirose M, Künstner A, Schilf P, Tietjen AK, Jöhren O, Huebbe P, Rimbach G, Rupp J, Schwaninger M, Busch H, Ibrahim SM.

Int J Mol Sci. 2019 May 13;20(9). pii: E2359. doi: 10.3390/ijms20092359.

3.

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.

Hirose M, Schilf P, Gupta Y, Zarse K, Künstner A, Fähnrich A, Busch H, Yin J, Wright MN, Ziegler A, Vallier M, Belheouane M, Baines JF, Tautz D, Johann K, Oelkrug R, Mittag J, Lehnert H, Othman A, Jöhren O, Schwaninger M, Prehn C, Adamski J, Shima K, Rupp J, Häsler R, Fuellen G, Köhling R, Ristow M, Ibrahim SM.

Sci Rep. 2018 Apr 12;8(1):5872. doi: 10.1038/s41598-018-24290-6.

4.

The LepR-mediated leptin transport across brain barriers controls food reward.

Di Spiezio A, Sandin ES, Dore R, Müller-Fielitz H, Storck SE, Bernau M, Mier W, Oster H, Jöhren O, Pietrzik CU, Lehnert H, Schwaninger M.

Mol Metab. 2018 Feb;8:13-22. doi: 10.1016/j.molmet.2017.12.001. Epub 2017 Dec 7.

5.

Mitochondrial gene polymorphism is associated with gut microbial communities in mice.

Hirose M, Künstner A, Schilf P, Sünderhauf A, Rupp J, Jöhren O, Schwaninger M, Sina C, Baines JF, Ibrahim SM.

Sci Rep. 2017 Nov 10;7(1):15293. doi: 10.1038/s41598-017-15377-7.

6.

Orexins/hypocretins and sex.

Jöhren O.

Peptides. 2018 Jan;99:115-116. doi: 10.1016/j.peptides.2017.10.014. Epub 2017 Oct 26. No abstract available.

PMID:
29107089
7.

The thermogenic effect of nesfatin-1 requires recruitment of the melanocortin system.

Dore R, Levata L, Gachkar S, Jöhren O, Mittag J, Lehnert H, Schulz C.

J Endocrinol. 2017 Nov;235(2):111-122. doi: 10.1530/JOE-17-0151. Epub 2017 Aug 29.

PMID:
28851749
8.

Transforming Growth Factor-β1/Activin Receptor-like Kinase 5-Mediated Cell Migration is Dependent on the Protein Proteinase-Activated Receptor 2 but not on Proteinase-Activated Receptor 2-Stimulated Gq-Calcium Signaling.

Ungefroren H, Witte D, Mihara K, Rauch BH, Henklein P, Jöhren O, Bonni S, Settmacher U, Lehnert H, Hollenberg MD, Kaufmann R, Gieseler F.

Mol Pharmacol. 2017 Nov;92(5):519-532. doi: 10.1124/mol.117.109017. Epub 2017 Aug 25.

PMID:
28842394
9.

Glucagon increase after chronic AT1 blockade is more likely related to an indirect leptin-dependent than to a pancreatic α-cell-dependent mechanism.

Mildner M, Müller-Fielitz H, Stölting I, Jöhren O, Steckelings M, Raasch W.

Naunyn Schmiedebergs Arch Pharmacol. 2017 May;390(5):505-518. doi: 10.1007/s00210-017-1346-7. Epub 2017 Jan 31.

PMID:
28144709
10.

Lifespan effects of mitochondrial mutations.

Hirose M, Schilf P, Gupta Y, Wright MN, Wright MN, Jöhren O, Wagner AE, Sina C, Ziegler A, Ristow M, Ibrahim SM.

Nature. 2016 Dec 14;540(7633):E13-E14. doi: 10.1038/nature20778. No abstract available.

PMID:
27974775
11.

Uncoupling protein 2 protects mice from aging.

Hirose M, Schilf P, Lange F, Mayer J, Reichart G, Maity P, Jöhren O, Schwaninger M, Scharffetter-Kochanek K, Sina C, Sadik CD, Köhling R, Miroux B, Ibrahim SM.

Mitochondrion. 2016 Sep;30:42-50. doi: 10.1016/j.mito.2016.06.004. Epub 2016 Jun 27.

PMID:
27364833
12.

Acute hypothalamo-pituitary-adrenal axis response to LPS-induced endotoxemia: expression pattern of kinin type B1 and B2 receptors.

Qadri F, Rimmele F, Mallis L, Häuser W, Dendorfer A, Jöhren O, Dominiak P, Leeb-Lundberg LM, Bader M.

Biol Chem. 2016 Jan 1;397(2):97-109. doi: 10.1515/hsz-2015-0206.

PMID:
26468906
13.

Nesfatin-1 increases energy expenditure and reduces food intake in rats.

Wernecke K, Lamprecht I, Jöhren O, Lehnert H, Schulz C.

Obesity (Silver Spring). 2014 Jul;22(7):1662-8. doi: 10.1002/oby.20736. Epub 2014 Mar 25.

14.

QRFP induces aldosterone production via PKC and T-type calcium channel-mediated pathways in human adrenocortical cells: evidence for a novel role of GPR103.

Ramanjaneya M, Karteris E, Chen J, Rucinski M, Ziolkowska A, Ahmed N, Kagerer S, Jöhren O, Lehnert H, Malendowicz LK, Randeva HS.

Am J Physiol Endocrinol Metab. 2013 Nov 1;305(9):E1049-58. doi: 10.1152/ajpendo.00191.2013. Epub 2013 Aug 20.

15.

High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice.

Barclay JL, Shostak A, Leliavski A, Tsang AH, Jöhren O, Müller-Fielitz H, Landgraf D, Naujokat N, van der Horst GT, Oster H.

Am J Physiol Endocrinol Metab. 2013 May 15;304(10):E1053-63. doi: 10.1152/ajpendo.00512.2012. Epub 2013 Mar 26.

16.

Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling.

Pientka FK, Hu J, Schindler SG, Brix B, Thiel A, Jöhren O, Fandrey J, Berchner-Pfannschmidt U, Depping R.

J Cell Sci. 2012 Nov 1;125(Pt 21):5168-76. doi: 10.1242/jcs.109041. Epub 2012 Sep 3.

17.

Endothelial cell-derived nitric oxide enhances aerobic glycolysis in astrocytes via HIF-1α-mediated target gene activation.

Brix B, Mesters JR, Pellerin L, Jöhren O.

J Neurosci. 2012 Jul 11;32(28):9727-35. doi: 10.1523/JNEUROSCI.0879-12.2012.

18.

Orexin A suppresses the growth of rat C6 glioma cells via a caspase-dependent mechanism.

Biegańska K, Sokołowska P, Jöhren O, Zawilska JB.

J Mol Neurosci. 2012 Nov;48(3):706-12. Epub 2012 May 17.

19.

Pioglitazone prevents capillary rarefaction in streptozotocin-diabetic rats independently of glucose control and vascular endothelial growth factor expression.

Ashoff A, Qadri F, Eggers R, Jöhren O, Raasch W, Dendorfer A.

J Vasc Res. 2012;49(3):260-6. doi: 10.1159/000335214. Epub 2012 Mar 27.

20.

Blood pressure response to angiotensin II is enhanced in obese Zucker rats and is attributed to an aldosterone-dependent mechanism.

Müller-Fielitz H, Lau M, Jöhren O, Stellmacher F, Schwaninger M, Raasch W.

Br J Pharmacol. 2012 Aug;166(8):2417-29. doi: 10.1111/j.1476-5381.2012.01953.x.

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