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Critical period inhibition of NKCC1 rectifies synapse plasticity in the somatosensory cortex and restores adult tactile response maps in fragile X mice.

He Q, Arroyo ED, Smukowski SN, Xu J, Piochon C, Savas JN, Portera-Cailliau C, Contractor A.

Mol Psychiatry. 2018 Apr 27. doi: 10.1038/s41380-018-0048-y. [Epub ahead of print]


Photoactivatable drugs for nicotinic optopharmacology.

Banala S, Arvin MC, Bannon NM, Jin XT, Macklin JJ, Wang Y, Peng C, Zhao G, Marshall JJ, Gee KR, Wokosin DL, Kim VJ, McIntosh JM, Contractor A, Lester HA, Kozorovitskiy Y, Drenan RM, Lavis LD.

Nat Methods. 2018 May;15(5):347-350. doi: 10.1038/nmeth.4637. Epub 2018 Mar 26.


Kainate Receptors Inhibit Glutamate Release Via Mobilization of Endocannabinoids in Striatal Direct Pathway Spiny Projection Neurons.

Marshall JJ, Xu J, Contractor A.

J Neurosci. 2018 Apr 18;38(16):3901-3910. doi: 10.1523/JNEUROSCI.1788-17.2018. Epub 2018 Mar 14.


Prevention of sudden cardiac death in athletes, sportspersons and marathoners in India.

Vora A, Burkule N, Contractor A, Bhargava K.

Indian Heart J. 2018 Jan - Feb;70(1):137-145. doi: 10.1016/j.ihj.2017.12.004. Epub 2017 Dec 15. Review.


Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome.

Pyronneau A, He Q, Hwang JY, Porch M, Contractor A, Zukin RS.

Sci Signal. 2017 Nov 7;10(504). pii: eaan0852. doi: 10.1126/scisignal.aan0852.


Delayed Maturation of Fast-Spiking Interneurons Is Rectified by Activation of the TrkB Receptor in the Mouse Model of Fragile X Syndrome.

Nomura T, Musial TF, Marshall JJ, Zhu Y, Remmers CL, Xu J, Nicholson DA, Contractor A.

J Neurosci. 2017 Nov 22;37(47):11298-11310. doi: 10.1523/JNEUROSCI.2893-16.2017. Epub 2017 Oct 16.


A novel role for dopamine signaling in the pathogenesis of bone loss from the atypical antipsychotic drug risperidone in female mice.

Motyl KJ, Beauchemin M, Barlow D, Le PT, Nagano K, Treyball A, Contractor A, Baron R, Rosen CJ, Houseknecht KL.

Bone. 2017 Oct;103:168-176. doi: 10.1016/j.bone.2017.07.008. Epub 2017 Jul 6.


Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.

Xu J, Marshall JJ, Fernandes HB, Nomura T, Copits BA, Procissi D, Mori S, Wang L, Zhu Y, Swanson GT, Contractor A.

Cell Rep. 2017 Feb 21;18(8):1848-1857. doi: 10.1016/j.celrep.2017.01.073.


Racial/ethnic differences moderate associations of coping strategies and posttraumatic stress disorder symptom clusters among women experiencing partner violence: a multigroup path analysis.

Weiss NH, Johnson CD, Contractor A, Peasant C, Swan SC, Sullivan TP.

Anxiety Stress Coping. 2017 May;30(3):347-363. doi: 10.1080/10615806.2016.1228900. Epub 2016 Sep 17.


Cardiac Rehabilitation Delivery Model for Low-Resource Settings: An International Council of Cardiovascular Prevention and Rehabilitation Consensus Statement.

Grace SL, Turk-Adawi KI, Contractor A, Atrey A, Campbell NR, Derman W, Ghisi GL, Sarkar BK, Yeo TJ, Lopez-Jimenez F, Buckley J, Hu D, Sarrafzadegan N.

Prog Cardiovasc Dis. 2016 Nov - Dec;59(3):303-322. doi: 10.1016/j.pcad.2016.08.004. Epub 2016 Aug 17. Review.


Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor.

Straub C, Noam Y, Nomura T, Yamasaki M, Yan D, Fernandes HB, Zhang P, Howe JR, Watanabe M, Contractor A, Tomita S.

Cell Rep. 2016 Jul 12;16(2):531-544. doi: 10.1016/j.celrep.2016.05.093. Epub 2016 Jun 23.


Cardiac rehabilitation delivery model for low-resource settings.

Grace SL, Turk-Adawi KI, Contractor A, Atrey A, Campbell N, Derman W, Melo Ghisi GL, Oldridge N, Sarkar BK, Yeo TJ, Lopez-Jimenez F, Mendis S, Oh P, Hu D, Sarrafzadegan N.

Heart. 2016 Sep 15;102(18):1449-55. doi: 10.1136/heartjnl-2015-309209. Epub 2016 May 15. Review.


Chronic Nicotine Mitigates Aberrant Inhibitory Motor Learning Induced by Motor Experience under Dopamine Deficiency.

Koranda JL, Krok AC, Xu J, Contractor A, McGehee DS, Beeler JA, Zhuang X.

J Neurosci. 2016 May 11;36(19):5228-40. doi: 10.1523/JNEUROSCI.2754-15.2016.


Factor Structure of the PTSD Checklist for DSM-5: Relationships Among Symptom Clusters, Anger, and Impulsivity.

Armour C, Contractor A, Shea T, Elhai JD, Pietrzak RH.

J Nerv Ment Dis. 2016 Feb;204(2):108-15. doi: 10.1097/NMD.0000000000000430.


Altered Neuronal and Circuit Excitability in Fragile X Syndrome.

Contractor A, Klyachko VA, Portera-Cailliau C.

Neuron. 2015 Aug 19;87(4):699-715. doi: 10.1016/j.neuron.2015.06.017. Review.


Subchronic phencyclidine treatment in adult mice increases GABAergic transmission and LTP threshold in the hippocampus.

Nomura T, Oyamada Y, Fernandes HB, Remmers CL, Xu J, Meltzer HY, Contractor A.

Neuropharmacology. 2016 Jan;100:90-7. doi: 10.1016/j.neuropharm.2015.04.012. Epub 2015 Apr 30.


Identifying latent profiles of posttraumatic stress and major depression symptoms in Canadian veterans: Exploring differences across profiles in health related functioning.

Armour C, Contractor A, Elhai JD, Stringer M, Lyle G, Forbes D, Richardson JD.

Psychiatry Res. 2015 Jul 30;228(1):1-7. doi: 10.1016/j.psychres.2015.03.011. Epub 2015 Apr 22.


Epac2 Mediates cAMP-Dependent Potentiation of Neurotransmission in the Hippocampus.

Fernandes HB, Riordan S, Nomura T, Remmers CL, Kraniotis S, Marshall JJ, Kukreja L, Vassar R, Contractor A.

J Neurosci. 2015 Apr 22;35(16):6544-53. doi: 10.1523/JNEUROSCI.0314-14.2015.


Double Dissociation of the Roles of Metabotropic Glutamate Receptor 5 and Oxytocin Receptor in Discrete Social Behaviors.

Mesic I, Guzman YF, Guedea AL, Jovasevic V, Corcoran KA, Leaderbrand K, Nishimori K, Contractor A, Radulovic J.

Neuropsychopharmacology. 2015 Sep;40(10):2337-46. doi: 10.1038/npp.2015.81. Epub 2015 Mar 31.


Hippocampal metaplasticity is required for the formation of temporal associative memories.

Xu J, Antion MD, Nomura T, Kraniotis S, Zhu Y, Contractor A.

J Neurosci. 2014 Dec 10;34(50):16762-73. doi: 10.1523/JNEUROSCI.2869-13.2014.

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