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Items: 1 to 20 of 71


Pleiotropic roles of the matricellular protein Sparc in tendon maturation and ageing.

Gehwolf R, Wagner A, Lehner C, Bradshaw AD, Scharler C, Niestrawska JA, Holzapfel GA, Bauer HC, Tempfer H, Traweger A.

Sci Rep. 2016 Sep 2;6:32635. doi: 10.1038/srep32635.


Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium.

Toba H, de Castro Brás LE, Baicu CF, Zile MR, Lindsey ML, Bradshaw AD.

Am J Physiol Endocrinol Metab. 2016 Jun 1;310(11):E1027-35. doi: 10.1152/ajpendo.00040.2016.


SPARC/osteonectin in mineralized tissue.

Rosset EM, Bradshaw AD.

Matrix Biol. 2016 May-Jul;52-54:78-87. doi: 10.1016/j.matbio.2016.02.001. Review.


Microbiome, a new dimension in cancer research.

Neto AG, Bradshaw AD, Pei Z.

Ann Transl Med. 2015 Sep;3(16):229. doi: 10.3978/j.issn.2305-5839.2015.08.07. No abstract available.


Dasatinib Attenuates Pressure Overload Induced Cardiac Fibrosis in a Murine Transverse Aortic Constriction Model.

Balasubramanian S, Pleasant DL, Kasiganesan H, Quinones L, Zhang Y, Sundararaj KP, Roche S, O'Connor R, Bradshaw AD, Kuppuswamy D.

PLoS One. 2015 Oct 12;10(10):e0140273. doi: 10.1371/journal.pone.0140273.


pGlcNAc Nanofiber Treatment of Cutaneous Wounds Stimulate Increased Tensile Strength and Reduced Scarring via Activation of Akt1.

Lindner HB, Felmly LM, Demcheva M, Seth A, Norris R, Bradshaw AD, Vournakis J, Muise-Helmericks RC.

PLoS One. 2015 May 8;10(5):e0127876. doi: 10.1371/journal.pone.0127876.


Lumican deficiency results in cardiomyocyte hypertrophy with altered collagen assembly.

Dupuis LE, Berger MG, Feldman S, Doucette L, Fowlkes V, Chakravarti S, Thibaudeau S, Alcala NE, Bradshaw AD, Kern CB.

J Mol Cell Cardiol. 2015 Jul;84:70-80. doi: 10.1016/j.yjmcc.2015.04.007.


Secreted protein acidic and rich in cysteine facilitates age-related cardiac inflammation and macrophage M1 polarization.

Toba H, de Castro Brás LE, Baicu CF, Zile MR, Lindsey ML, Bradshaw AD.

Am J Physiol Cell Physiol. 2015 Jun 15;308(12):C972-82. doi: 10.1152/ajpcell.00402.2014.


Decreased Mechanical Strength and Collagen Content in SPARC-Null Periodontal Ligament Is Reversed by Inhibition of Transglutaminase Activity.

Trombetta-eSilva J, Rosset EA, Hepfer RG, Wright GJ, Baicu C, Yao H, Bradshaw AD.

J Bone Miner Res. 2015 Oct;30(10):1914-24. doi: 10.1002/jbmr.2522.


Myocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titin.

Zile MR, Baicu CF, Ikonomidis JS, Stroud RE, Nietert PJ, Bradshaw AD, Slater R, Palmer BM, Van Buren P, Meyer M, Redfield MM, Bull DA, Granzier HL, LeWinter MM.

Circulation. 2015 Apr 7;131(14):1247-59. doi: 10.1161/CIRCULATIONAHA.114.013215.


Age and SPARC change the extracellular matrix composition of the left ventricle.

de Castro Brás LE, Toba H, Baicu CF, Zile MR, Weintraub ST, Lindsey ML, Bradshaw AD.

Biomed Res Int. 2014;2014:810562. doi: 10.1155/2014/810562.


Myocardial fibroblast-matrix interactions and potential therapeutic targets.

Goldsmith EC, Bradshaw AD, Zile MR, Spinale FG.

J Mol Cell Cardiol. 2014 May;70:92-9. doi: 10.1016/j.yjmcc.2014.01.008. Review.


The effects of age and the expression of SPARC on extracellular matrix production by cardiac fibroblasts in 3-D cultures.

Trombetta-eSilva J, Eadie EP, Zhang Y, Norris RA, Borg TK, Bradshaw AD.

PLoS One. 2013 Nov 6;8(11):e79715. doi: 10.1371/journal.pone.0079715.


Relationship between anisotropic diffusion properties and tissue morphology in porcine TMJ disc.

Shi C, Wright GJ, Ex-Lubeskie CL, Bradshaw AD, Yao H.

Osteoarthritis Cartilage. 2013 Apr;21(4):625-33. doi: 10.1016/j.joca.2013.01.010.


Cellular mechanisms of tissue fibrosis. 2. Contributory pathways leading to myocardial fibrosis: moving beyond collagen expression.

Goldsmith EC, Bradshaw AD, Spinale FG.

Am J Physiol Cell Physiol. 2013 Mar 1;304(5):C393-402. doi: 10.1152/ajpcell.00347.2012. Review.


β3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouse.

Balasubramanian S, Quinones L, Kasiganesan H, Zhang Y, Pleasant DL, Sundararaj KP, Zile MR, Bradshaw AD, Kuppuswamy D.

PLoS One. 2012;7(9):e45076. doi: 10.1371/journal.pone.0045076.


Time course of right ventricular pressure-overload induced myocardial fibrosis: relationship to changes in fibroblast postsynthetic procollagen processing.

Baicu CF, Li J, Zhang Y, Kasiganesan H, Cooper G 4th, Zile MR, Bradshaw AD.

Am J Physiol Heart Circ Physiol. 2012 Nov 1;303(9):H1128-34. doi: 10.1152/ajpheart.00482.2012.


The Function of SPARC as a Mediator of Fibrosis.

Trombetta-Esilva J, Bradshaw AD.

Open Rheumatol J. 2012;6:146-55. doi: 10.2174/1874312901206010146.


Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload.

Baicu CF, Zhang Y, Van Laer AO, Renaud L, Zile MR, Bradshaw AD.

Am J Physiol Heart Circ Physiol. 2012 Jul 15;303(2):H234-40. doi: 10.1152/ajpheart.00227.2012.

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