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Items: 1 to 20 of 251


Removal of HIV DNA by CRISPR from Patient Blood Engrafts in Humanized Mice.

Bella R, Kaminski R, Mancuso P, Young WB, Chen C, Sariyer R, Fischer T, Amini S, Ferrante P, Jacobson JM, Kashanchi F, Khalili K.

Mol Ther Nucleic Acids. 2018 Sep 7;12:275-282. doi: 10.1016/j.omtn.2018.05.021. Epub 2018 Jun 19.


Sex and Gender Differences in Migraine-Evaluating Knowledge Gaps.

Schroeder RA, Brandes J, Buse DC, Calhoun A, Eikermann-Haerter K, Golden K, Halker R, Kempner J, Maleki N, Moriarty M, Pavlovic J, Shapiro RE, Starling A, Young WB, Nebel RA.

J Womens Health (Larchmt). 2018 Aug;27(8):965-973. doi: 10.1089/jwh.2018.7274.


Association Between Pre-season Training and Performance in Elite Australian Football.

McCaskie CJ, Young WB, Fahrner BB, Sim M.

Int J Sports Physiol Perform. 2018 Aug 17:1-25. doi: 10.1123/ijspp.2018-0076. [Epub ahead of print]


Gradual vs. Maximal Acceleration: Their Influence on the Prescription of Maximal Speed Sprinting in Team Sport Athletes.

Young WB, Duthie GM, James LP, Talpey SW, Benton DT, Kilfoyle A.

Sports (Basel). 2018 Jul 21;6(3). pii: E66. doi: 10.3390/sports6030066.


Noncovalent inhibition of C481S Bruton tyrosine kinase by GDC-0853: a new treatment strategy for ibrutinib-resistant CLL.

Reiff SD, Muhowski EM, Guinn D, Lehman A, Fabian CA, Cheney C, Mantel R, Smith L, Johnson AJ, Young WB, Johnson AR, Liu L, Byrd JC, Woyach JA.

Blood. 2018 Sep 6;132(10):1039-1049. doi: 10.1182/blood-2017-10-809020. Epub 2018 Jul 17.


Association Between Pre-season Training and Performance in Elite Australian Football.

McCaskie CJ, Young WB, Fahrner BB, Sim M.

Int J Sports Physiol Perform. 2018 Jun 12:1-25. doi: 10.1123/ijspp.2018-0086. [Epub ahead of print]


Relationship Between Selected Physical Qualities, Bowling Kinematics, and Pace Bowling Skill in Club-Standard Cricketers.

Feros SA, Young WB, OʼBrien BJ.

J Strength Cond Res. 2018 Apr 26. doi: 10.1519/JSC.0000000000002587. [Epub ahead of print]


Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development.

Crawford JJ, Johnson AR, Misner DL, Belmont LD, Castanedo G, Choy R, Coraggio M, Dong L, Eigenbrot C, Erickson R, Ghilardi N, Hau J, Katewa A, Kohli PB, Lee W, Lubach JW, McKenzie BS, Ortwine DF, Schutt L, Tay S, Wei B, Reif K, Liu L, Wong H, Young WB.

J Med Chem. 2018 Mar 22;61(6):2227-2245. doi: 10.1021/acs.jmedchem.7b01712. Epub 2018 Feb 23.


De-Stigmatizing Migraine - With Words.

Young WB.

Headache. 2018 Feb;58(2):319-321. doi: 10.1111/head.13209. Epub 2017 Nov 15. No abstract available.


Quantifying Cricket Fast-Bowling Skill.

Feros SA, Young WB, O'Brien BJ.

Int J Sports Physiol Perform. 2018 Aug 1;13(7):830-838. doi: 10.1123/ijspp.2017-0169. Epub 2018 Jul 27. Review.


Medicinal Chemistry: Where Are All the Women?

Huryn DM, Bolognesi ML, Young WB.

ACS Med Chem Lett. 2017 Aug 25;8(9):900-902. doi: 10.1021/acsmedchemlett.7b00321. eCollection 2017 Sep 14.


Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties.

Wang X, Barbosa J, Blomgren P, Bremer MC, Chen J, Crawford JJ, Deng W, Dong L, Eigenbrot C, Gallion S, Hau J, Hu H, Johnson AR, Katewa A, Kropf JE, Lee SH, Liu L, Lubach JW, Macaluso J, Maciejewski P, Mitchell SA, Ortwine DF, DiPaolo J, Reif K, Scheerens H, Schmitt A, Wong H, Xiong JM, Xu J, Zhao Z, Zhou F, Currie KS, Young WB.

ACS Med Chem Lett. 2017 May 3;8(6):608-613. doi: 10.1021/acsmedchemlett.7b00103. eCollection 2017 Jun 8.


The Reliability and Sensitivity of Performance Measures in a Novel Pace-Bowling Test.

Feros SA, Young WB, O'Brien BJ.

Int J Sports Physiol Perform. 2018 Feb 1;13(2):151-155. doi: 10.1123/ijspp.2017-0140. Epub 2018 Feb 12.


CRISPR Editing Technology in Biological and Biomedical Investigation.

White MK, Kaminski R, Young WB, Roehm PC, Khalili K.

J Cell Biochem. 2017 Nov;118(11):3586-3594. doi: 10.1002/jcb.26099. Epub 2017 Jul 4. Review.


Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

Katewa A, Wang Y, Hackney JA, Huang T, Suto E, Ramamoorthi N, Austin CD, Bremer M, Chen JZ, Crawford JJ, Currie KS, Blomgren P, DeVoss J, DiPaolo JA, Hau J, Johnson A, Lesch J, DeForge LE, Lin Z, Liimatta M, Lubach JW, McVay S, Modrusan Z, Nguyen A, Poon C, Wang J, Liu L, Lee WP, Wong H, Young WB, Townsend MJ, Reif K.

JCI Insight. 2017 Apr 6;2(7):e90111. doi: 10.1172/jci.insight.90111.


In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models.

Yin C, Zhang T, Qu X, Zhang Y, Putatunda R, Xiao X, Li F, Xiao W, Zhao H, Dai S, Qin X, Mo X, Young WB, Khalili K, Hu W.

Mol Ther. 2017 May 3;25(5):1168-1186. doi: 10.1016/j.ymthe.2017.03.012. Epub 2017 Mar 30.


Specific and Stable Suppression of HIV Provirus Expression In Vitro by Chimeric Zinc Finger DNA Methyltransferase 1.

Deng J, Qu X, Lu P, Yang X, Zhu Y, Ji H, Wang Y, Jiang Z, Li X, Zhong Y, Yang H, Pan H, Young WB, Zhu H.

Mol Ther Nucleic Acids. 2017 Mar 17;6:233-242. doi: 10.1016/j.omtn.2017.01.002. Epub 2017 Jan 24.


Reliability of a Field Test of Defending and Attacking Agility in Australian Football and Relationships to Reactive Strength.

Young WB, Murray MP.

J Strength Cond Res. 2017 Feb;31(2):509-516. doi: 10.1519/JSC.0000000000001498.


Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats.

Erickson RI, Schutt LK, Tarrant JM, McDowell M, Liu L, Johnson AR, Lewin-Koh SC, Hedehus M, Ross J, Carano RA, Staflin K, Zhong F, Crawford JJ, Zhong S, Reif K, Katewa A, Wong H, Young WB, Dambach DM, Misner DL.

J Pharmacol Exp Ther. 2017 Jan;360(1):226-238. Epub 2016 Nov 7.


Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations.

Johnson AR, Kohli PB, Katewa A, Gogol E, Belmont LD, Choy R, Penuel E, Burton L, Eigenbrot C, Yu C, Ortwine DF, Bowman K, Franke Y, Tam C, Estevez A, Mortara K, Wu J, Li H, Lin M, Bergeron P, Crawford JJ, Young WB.

ACS Chem Biol. 2016 Oct 21;11(10):2897-2907. Epub 2016 Sep 7.


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