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Items: 1 to 20 of 38


Activin-A Is a Pro-Inflammatory Regulator in Type-2-Driven Upper Airway Disease.

Chaker AM, Zissler UM, Poulos N, Wagenmann M, Bas M, Gürth F, Xanthou G, Schmidt-Weber C.

Int Arch Allergy Immunol. 2018;176(1):15-25. doi: 10.1159/000487930. Epub 2018 Apr 13.


Activated Leukocyte Cell Adhesion Molecule: A Novel Regulator of Allergic Inflammation in the Airways.

Semitekolou M, Xanthou G.

Am J Respir Crit Care Med. 2018 Apr 15;197(8):973-975. doi: 10.1164/rccm.201801-0196ED. No abstract available.


Upper and lower airway remodelling mechanisms in asthma, allergic rhinitis and chronic rhinosinusitis: The one airway concept revisited.

Samitas K, Carter A, Kariyawasam HH, Xanthou G.

Allergy. 2018 May;73(5):993-1002. doi: 10.1111/all.13373. Epub 2017 Dec 22. Review.


Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in mice.

Karampetsou M, Ardah MT, Semitekolou M, Polissidis A, Samiotaki M, Kalomoiri M, Majbour N, Xanthou G, El-Agnaf OMA, Vekrellis K.

Sci Rep. 2017 Nov 28;7(1):16533. doi: 10.1038/s41598-017-15813-8.


Dendritic cells conditioned by activin A-induced regulatory T cells exhibit enhanced tolerogenic properties and protect against experimental asthma.

Semitekolou M, Morianos I, Banos A, Konstantopoulos D, Adamou-Tzani M, Sparwasser T, Xanthou G.

J Allergy Clin Immunol. 2018 Feb;141(2):671-684.e7. doi: 10.1016/j.jaci.2017.03.047. Epub 2017 Jun 1.


Innate immunity as the orchestrator of allergic airway inflammation and resolution in asthma.

Thiriou D, Morianos I, Xanthou G, Samitas K.

Int Immunopharmacol. 2017 Jul;48:43-54. doi: 10.1016/j.intimp.2017.04.027. Epub 2017 May 3. Review.


Addressing unmet needs in understanding asthma mechanisms: From the European Asthma Research and Innovation Partnership (EARIP) Work Package (WP)2 collaborators.

Edwards MR, Saglani S, Schwarze J, Skevaki C, Smith JA, Ainsworth B, Almond M, Andreakos E, Belvisi MG, Chung KF, Cookson W, Cullinan P, Hawrylowicz C, Lommatzsch M, Jackson D, Lutter R, Marsland B, Moffatt M, Thomas M, Virchow JC, Xanthou G, Edwards J, Walker S, Johnston SL; members of the EARIP WP2 working group.

Eur Respir J. 2017 May 1;49(5). pii: 1602448. doi: 10.1183/13993003.02448-2016. Print 2017 May. Review.


Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses.

Tousa S, Semitekolou M, Morianos I, Banos A, Trochoutsou AI, Brodie TM, Poulos N, Samitas K, Kapasa M, Konstantopoulos D, Paraskevopoulos G, Gaga M, Hawrylowicz CM, Sallusto F, Xanthou G.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2891-E2900. doi: 10.1073/pnas.1616942114. Epub 2017 Mar 20.


Activin-A is overexpressed in severe asthma and is implicated in angiogenic processes.

Samitas K, Poulos N, Semitekolou M, Morianos I, Tousa S, Economidou E, Robinson DS, Kariyawasam HH, Zervas E, Corrigan CJ, Ying S, Xanthou G, Gaga M.

Eur Respir J. 2016 Mar;47(3):769-82. doi: 10.1183/13993003.00437-2015. Epub 2016 Feb 11.


Vitamin-D in the Immune System: Genomic and Non-Genomic Actions.

Trochoutsou AI, Kloukina V, Samitas K, Xanthou G.

Mini Rev Med Chem. 2015;15(11):953-63. Review.


Tolerogenic signaling by pulmonary CD1c+ dendritic cells induces regulatory T cells in patients with chronic obstructive pulmonary disease by IL-27/IL-10/inducible costimulator ligand.

Tsoumakidou M, Tousa S, Semitekolou M, Panagiotou P, Panagiotou A, Morianos I, Litsiou E, Trochoutsou AI, Konstantinou M, Potaris K, Footitt J, Mallia P, Zakynthinos S, Johnston SL, Xanthou G.

J Allergy Clin Immunol. 2014 Oct;134(4):944-954.e8. doi: 10.1016/j.jaci.2014.05.045. Epub 2014 Jul 19.


Circulating conventional and plasmacytoid dendritic cell subsets display distinct kinetics during in vivo repeated allergen skin challenges in atopic subjects.

Vittorakis S, Samitas K, Tousa S, Zervas E, Aggelakopoulou M, Semitekolou M, Panoutsakopoulou V, Xanthou G, Gaga M.

Biomed Res Int. 2014;2014:231036. doi: 10.1155/2014/231036. Epub 2014 Apr 28.


Activin-A exerts a crucial anti-inflammatory role in neonatal infections.

Petrakou E, Fotopoulos S, Anagnostakou M, Anatolitou F, Samitas K, Semitekolou M, Xanthou G, Xanthou M.

Pediatr Res. 2013 Dec;74(6):675-81. doi: 10.1038/pr.2013.159. Epub 2013 Sep 3.


Osteopontin is increased in the bronchoalveolar lavage fluid and bronchial tissue of smoking asthmatics.

Samitas K, Zervas E, Xanthou G, Panoutsakopoulou V, Gaga M.

Cytokine. 2013 Mar;61(3):713-5. doi: 10.1016/j.cyto.2012.12.028. Epub 2013 Feb 4. No abstract available.


Activin-A: a novel critical regulator of allergic asthma.

Kariyawasam HH, Semitekolou M, Robinson DS, Xanthou G.

Clin Exp Allergy. 2011 Nov;41(11):1505-14. doi: 10.1111/j.1365-2222.2011.03784.x. Epub 2011 Jun 1. Review.


Regulation of adverse remodelling by osteopontin in a genetic heart failure model.

Psarras S, Mavroidis M, Sanoudou D, Davos CH, Xanthou G, Varela AE, Panoutsakopoulou V, Capetanaki Y.

Eur Heart J. 2012 Aug;33(15):1954-63. doi: 10.1093/eurheartj/ehr119. Epub 2011 Apr 26.


Neurohormonal activity and vascular properties late after aortic coarctation repair.

Moutafi AC, Alissafi T, Chamakou A, Chryssanthopoulos S, Thanopoulos V, Dellos C, Xanthou G, Tousoulis D, Stefanadis C, Gatzoulis MA, Davos CH.

Int J Cardiol. 2012 Sep 6;159(3):211-6. doi: 10.1016/j.ijcard.2011.02.071. Epub 2011 Mar 22.


Osteopontin expression and relation to disease severity in human asthma.

Samitas K, Zervas E, Vittorakis S, Semitekolou M, Alissafi T, Bossios A, Gogos H, Economidou E, Lötvall J, Xanthou G, Panoutsakopoulou V, Gaga M.

Eur Respir J. 2011 Feb;37(2):331-41. doi: 10.1183/09031936.00017810. Epub 2010 Jun 18.


Activin and transforming growth factor-beta signaling pathways are activated after allergen challenge in mild asthma.

Kariyawasam HH, Pegorier S, Barkans J, Xanthou G, Aizen M, Ying S, Kay AB, Lloyd CM, Robinson DS.

J Allergy Clin Immunol. 2009 Sep;124(3):454-62. doi: 10.1016/j.jaci.2009.06.022.


Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease.

Semitekolou M, Alissafi T, Aggelakopoulou M, Kourepini E, Kariyawasam HH, Kay AB, Robinson DS, Lloyd CM, Panoutsakopoulou V, Xanthou G.

J Exp Med. 2009 Aug 3;206(8):1769-85. doi: 10.1084/jem.20082603. Epub 2009 Jul 20.

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