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Items: 1 to 20 of 153

1.

Urine biomarkers of chronic kidney damage and renal functional decline in childhood-onset systemic lupus erythematosus.

Brunner HI, Gulati G, Klein-Gitelman MS, Rouster-Stevens KA, Tucker L, Ardoin SP, Onel KB, Mainville R, Turnier J, Aydin POA, Witte D, Huang B, Bennett MR, Devarajan P.

Pediatr Nephrol. 2018 Aug 29. doi: 10.1007/s00467-018-4049-5. [Epub ahead of print]

PMID:
30159624
2.

Safety and Immunogenicity of Seven Dosing Regimens of the Candidate RTS,S/AS01E Malaria Vaccine Integrated Within an Expanded Program on Immunization Regimen: A Phase II, Single-Center, Open, Controlled Trial in Infants in Malawi.

Witte D, Cunliffe NA, Turner AM, Ngulube E, Ofori-Anyinam O, Vekemans J, Chimpeni P, Lievens M, Wilson TP, Njiram'madzi J, Mendoza YG, Leach A.

Pediatr Infect Dis J. 2018 May;37(5):483-491. doi: 10.1097/INF.0000000000001937.

PMID:
29432383
3.

The impact of lignin downregulation on alfalfa yield, chemical composition, and in vitro gas production.

Getachew G, Laca EA, Putnam DH, Witte D, McCaslin M, Ortega KP, DePeters EJ.

J Sci Food Agric. 2018 Aug;98(11):4205-4215. doi: 10.1002/jsfa.8942. Epub 2018 Mar 25.

PMID:
29406620
4.

The Role of PAR2 in TGF-β1-Induced ERK Activation and Cell Motility.

Ungefroren H, Witte D, Fiedler C, Gädeken T, Kaufmann R, Lehnert H, Gieseler F, Rauch BH.

Int J Mol Sci. 2017 Dec 20;18(12). pii: E2776. doi: 10.3390/ijms18122776.

5.

Negative regulation of TGF-β1-induced MKK6-p38 and MEK-ERK signalling and epithelial-mesenchymal transition by Rac1b.

Witte D, Otterbein H, Förster M, Giehl K, Zeiser R, Lehnert H, Ungefroren H.

Sci Rep. 2017 Dec 11;7(1):17313. doi: 10.1038/s41598-017-15170-6.

6.

Correction of GSK3β at young age prevents muscle pathology in mice with myotonic dystrophy type 1.

Wei C, Stock L, Valanejad L, Zalewski ZA, Karns R, Puymirat J, Nelson D, Witte D, Woodgett J, Timchenko NA, Timchenko L.

FASEB J. 2018 Apr;32(4):2073-2085. doi: 10.1096/fj.201700700R. Epub 2018 Jan 5.

PMID:
29203592
7.

Proteinase-Activated Receptor 2 May Drive Cancer Progression by Facilitating TGF-β Signaling.

Ungefroren H, Witte D, Rauch BH, Settmacher U, Lehnert H, Gieseler F, Kaufmann R.

Int J Mol Sci. 2017 Nov 22;18(11). pii: E2494. doi: 10.3390/ijms18112494. Review.

8.

Urine S100 proteins as potential biomarkers of lupus nephritis activity.

Turnier JL, Fall N, Thornton S, Witte D, Bennett MR, Appenzeller S, Klein-Gitelman MS, Grom AA, Brunner HI.

Arthritis Res Ther. 2017 Oct 24;19(1):242. doi: 10.1186/s13075-017-1444-4.

9.

TGF-β1-induced cell migration in pancreatic carcinoma cells is RAC1 and NOX4-dependent and requires RAC1 and NOX4-dependent activation of p38 MAPK.

Witte D, Bartscht T, Kaufmann R, Pries R, Settmacher U, Lehnert H, Ungefroren H.

Oncol Rep. 2017 Dec;38(6):3693-3701. doi: 10.3892/or.2017.6027. Epub 2017 Oct 12.

PMID:
29039574
10.

Transforming Growth Factor-β1/Activin Receptor-like Kinase 5-Mediated Cell Migration is Dependent on the Protein Proteinase-Activated Receptor 2 but not on Proteinase-Activated Receptor 2-Stimulated Gq-Calcium Signaling.

Ungefroren H, Witte D, Mihara K, Rauch BH, Henklein P, Jöhren O, Bonni S, Settmacher U, Lehnert H, Hollenberg MD, Kaufmann R, Gieseler F.

Mol Pharmacol. 2017 Nov;92(5):519-532. doi: 10.1124/mol.117.109017. Epub 2017 Aug 25.

PMID:
28842394
11.

The non-coding RNA landscape of human hematopoiesis and leukemia.

Schwarzer A, Emmrich S, Schmidt F, Beck D, Ng M, Reimer C, Adams FF, Grasedieck S, Witte D, Käbler S, Wong JWH, Shah A, Huang Y, Jammal R, Maroz A, Jongen-Lavrencic M, Schambach A, Kuchenbauer F, Pimanda JE, Reinhardt D, Heckl D, Klusmann JH.

Nat Commun. 2017 Aug 9;8(1):218. doi: 10.1038/s41467-017-00212-4.

12.

Urine Biomarkers to Predict Response to Lupus Nephritis Therapy in Children and Young Adults.

Brunner HI, Bennett MR, Gulati G, Abulaban K, Klein-Gitelman MS, Ardoin SP, Tucker LB, Rouster-Stevens KA, Witte D, Ying J, Devarajan P.

J Rheumatol. 2017 Aug;44(8):1239-1248. doi: 10.3899/jrheum.161128. Epub 2017 Jun 15.

PMID:
28620062
13.

FXR-Gankyrin axis is involved in development of pediatric liver cancer.

Valanejad L, Lewis K, Wright M, Jiang Y, D'Souza A, Karns R, Sheridan R, Gupta A, Bove K, Witte D, Geller J, Tiao G, Nelson DL, Timchenko L, Timchenko N.

Carcinogenesis. 2017 Jul 1;38(7):738-747. doi: 10.1093/carcin/bgx050.

14.

Inter-observer variability of the histological classification of lupus glomerulonephritis in children.

Oni L, Beresford MW, Witte D, Chatzitolios A, Sebire N, Abulaban K, Shukla R, Ying J, Brunner HI.

Lupus. 2017 Oct;26(11):1205-1211. doi: 10.1177/0961203317706558. Epub 2017 May 7.

PMID:
28478696
15.

The role of small GTPases of the Rho/Rac family in TGF-β-induced EMT and cell motility in cancer.

Ungefroren H, Witte D, Lehnert H.

Dev Dyn. 2018 Mar;247(3):451-461. doi: 10.1002/dvdy.24505. Epub 2017 May 30. Review.

PMID:
28390160
16.

Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease.

Pandey MK, Burrow TA, Rani R, Martin LJ, Witte D, Setchell KD, Mckay MA, Magnusen AF, Zhang W, Liou B, Köhl J, Grabowski GA.

Nature. 2017 Mar 2;543(7643):108-112. doi: 10.1038/nature21368. Epub 2017 Feb 22.

PMID:
28225753
17.

Successful Simultaneous Liver-Kidney Transplantation in the Presence of Multiple High-Titered Class I and II Antidonor HLA Antibodies.

Paterno F, Girnita A, Brailey P, Witte D, Wang J, Cuffy MC, Diwan T, Tremblay S, Revollo JY, Alloway RR, Schoech MR, Anwar N, Shah SA, Woodle SE.

Transplant Direct. 2016 Nov 23;2(12):e121. eCollection 2016 Dec.

18.

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.

Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, Ahluwalia TS, Arking DE, Bihlmeyer NA, Böger CA, Carroll RJ, Chasman DI, Cornelis MC, Dehghan A, Faul JD, Feitosa MF, Gambaro G, Gasparini P, Giulianini F, Heid I, Huang J, Imboden M, Jackson AU, Jeff J, Jhun MA, Katz R, Kifley A, Kilpeläinen TO, Kumar A, Laakso M, Li-Gao R, Lohman K, Lu Y, Mägi R, Malerba G, Mihailov E, Mohlke KL, Mook-Kanamori DO, Robino A, Ruderfer D, Salvi E, Schick UM, Schulz CA, Smith AV, Smith JA, Traglia M, Yerges-Armstrong LM, Zhao W, Goodarzi MO, Kraja AT, Liu C, Wessel J; CHARGE Glycemic-T2D Working Group,; CHARGE Blood Pressure Working Group,, Boerwinkle E, Borecki IB, Bork-Jensen J, Bottinger EP, Braga D, Brandslund I, Brody JA, Campbell A, Carey DJ, Christensen C, Coresh J, Crook E, Curhan GC, Cusi D, de Boer IH, de Vries AP, Denny JC, Devuyst O, Dreisbach AW, Endlich K, Esko T, Franco OH, Fulop T, Gerhard GS, Glümer C, Gottesman O, Grarup N, Gudnason V, Hansen T, Harris TB, Hayward C, Hocking L, Hofman A, Hu FB, Husemoen LL, Jackson RD, Jørgensen T, Jørgensen ME, Kähönen M, Kardia SL, König W, Kooperberg C, Kriebel J, Launer LJ, Lauritzen T, Lehtimäki T, Levy D, Linksted P, Linneberg A, Liu Y, Loos RJ, Lupo A, Meisinger C, Melander O, Metspalu A, Mitchell P, Nauck M, Nürnberg P, Orho-Melander M, Parsa A, Pedersen O, Peters A, Peters U, Polasek O, Porteous D, Probst-Hensch NM, Psaty BM, Qi L, Raitakari OT, Reiner AP, Rettig R, Ridker PM, Rivadeneira F, Rossouw JE, Schmidt F, Siscovick D, Soranzo N, Strauch K, Toniolo D, Turner ST, Uitterlinden AG, Ulivi S, Velayutham D, Völker U, Völzke H, Waldenberger M, Wang JJ, Weir DR, Witte D, Kuivaniemi H, Fox CS, Franceschini N, Goessling W, Köttgen A, Chu AY.

J Am Soc Nephrol. 2017 Mar;28(3):981-994. doi: 10.1681/ASN.2016020131. Epub 2016 Dec 5.

19.

Proteinase-Activated Receptor 2 Is a Novel Regulator of TGF-β Signaling in Pancreatic Cancer.

Witte D, Zeeh F, Gädeken T, Gieseler F, Rauch BH, Settmacher U, Kaufmann R, Lehnert H, Ungefroren H.

J Clin Med. 2016 Nov 30;5(12). pii: E111. Review.

20.

Effect of human rotavirus vaccine on severe diarrhea in African infants.

Madhi SA, Cunliffe NA, Steele D, Witte D, Kirsten M, Louw C, Ngwira B, Victor JC, Gillard PH, Cheuvart BB, Han HH, Neuzil KM.

Malawi Med J. 2016 Sep;28(3):108-114.

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