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Items: 1 to 20 of 154


Electronic Cigarettes and the Lung Proteome.

Shields PG, Song MA, Freudenheim JL, Brasky TM, Mathe E, McElroy JP, Hummon AB, Wewers MD.

Am J Respir Crit Care Med. 2018 Aug 28. doi: 10.1164/rccm.201806-1151LE. [Epub ahead of print] No abstract available.


Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes.

Hoang KV, Rajaram MVS, Curry HM, Gavrilin MA, Wewers MD, Schlesinger LS.

Front Immunol. 2018 Mar 26;9:561. doi: 10.3389/fimmu.2018.00561. eCollection 2018.


Microparticulate Caspase 1 Regulates Gasdermin D and Pulmonary Vascular Endothelial Cell Injury.

Mitra S, Exline M, Habyarimana F, Gavrilin MA, Baker PJ, Masters SL, Wewers MD, Sarkar A.

Am J Respir Cell Mol Biol. 2018 Jul;59(1):56-64. doi: 10.1165/rcmb.2017-0393OC.


Exposure to human alveolar lining fluid enhances Mycobacterium bovis BCG vaccine efficacy against Mycobacterium tuberculosis infection in a CD8+ T-cell-dependent manner.

Moliva JI, Hossfeld AP, Canan CH, Dwivedi V, Wewers MD, Beamer G, Turner J, Torrelles JB.

Mucosal Immunol. 2018 May;11(3):968-978. doi: 10.1038/mi.2017.80. Epub 2017 Sep 20.


Modifications of Pseudomonas aeruginosa cell envelope in the cystic fibrosis airway alters interactions with immune cells.

Hill PJ, Scordo JM, Arcos J, Kirkby SE, Wewers MD, Wozniak DJ, Torrelles JB.

Sci Rep. 2017 Jul 6;7(1):4761. doi: 10.1038/s41598-017-05253-9.


A Review of Pulmonary Toxicity of Electronic Cigarettes in the Context of Smoking: A Focus on Inflammation.

Shields PG, Berman M, Brasky TM, Freudenheim JL, Mathe E, McElroy JP, Song MA, Wewers MD.

Cancer Epidemiol Biomarkers Prev. 2017 Aug;26(8):1175-1191. doi: 10.1158/1055-9965.EPI-17-0358. Epub 2017 Jun 22. Review.


Mycobacterium tuberculosis Cell Wall Fragments Released upon Bacterial Contact with the Human Lung Mucosa Alter the Neutrophil Response to Infection.

Scordo JM, Arcos J, Kelley HV, Diangelo L, Sasindran SJ, Youngmin E, Wewers MD, Wang SH, Balada-Llasat JM, Torrelles JB.

Front Immunol. 2017 Mar 20;8:307. doi: 10.3389/fimmu.2017.00307. eCollection 2017.


The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.

Ratner D, Orning MP, Proulx MK, Wang D, Gavrilin MA, Wewers MD, Alnemri ES, Johnson PF, Lee B, Mecsas J, Kayagaki N, Goguen JD, Lien E.

PLoS Pathog. 2016 Dec 2;12(12):e1006035. doi: 10.1371/journal.ppat.1006035. eCollection 2016 Dec.


IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae.

Sundaram K, Rahman MA, Mitra S, Knoell DL, Woodiga SA, King SJ, Wewers MD.

PLoS One. 2016 Sep 6;11(9):e0161931. doi: 10.1371/journal.pone.0161931. eCollection 2016.


Blood-Borne Lipopolysaccharide Is Rapidly Eliminated by Liver Sinusoidal Endothelial Cells via High-Density Lipoprotein.

Yao Z, Mates JM, Cheplowitz AM, Hammer LP, Maiseyeu A, Phillips GS, Wewers MD, Rajaram MV, Robinson JM, Anderson CL, Ganesan LP.

J Immunol. 2016 Sep 15;197(6):2390-9. doi: 10.4049/jimmunol.1600702. Epub 2016 Aug 17.


Ethanol and Other Short-Chain Alcohols Inhibit NLRP3 Inflammasome Activation through Protein Tyrosine Phosphatase Stimulation.

Hoyt LR, Ather JL, Randall MJ, DePuccio DP, Landry CC, Wewers MD, Gavrilin MA, Poynter ME.

J Immunol. 2016 Aug 15;197(4):1322-34. doi: 10.4049/jimmunol.1600406. Epub 2016 Jul 15.


T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.

Martin BN, Wang C, Zhang CJ, Kang Z, Gulen MF, Zepp JA, Zhao J, Bian G, Do JS, Min B, Pavicic PG Jr, El-Sanadi C, Fox PL, Akitsu A, Iwakura Y, Sarkar A, Wewers MD, Kaiser WJ, Mocarski ES, Rothenberg ME, Hise AG, Dubyak GR, Ransohoff RM, Li X.

Nat Immunol. 2016 May;17(5):583-92. doi: 10.1038/ni.3389. Epub 2016 Mar 21.


Mononuclear Phagocyte-Derived Microparticulate Caspase-1 Induces Pulmonary Vascular Endothelial Cell Injury.

Mitra S, Wewers MD, Sarkar A.

PLoS One. 2015 Dec 28;10(12):e0145607. doi: 10.1371/journal.pone.0145607. eCollection 2015.


Monocyte Caspase-1 Is Released in a Stable, Active High Molecular Weight Complex Distinct from the Unstable Cell Lysate-Activated Caspase-1.

Shamaa OR, Mitra S, Gavrilin MA, Wewers MD.

PLoS One. 2015 Nov 24;10(11):e0142203. doi: 10.1371/journal.pone.0142203. eCollection 2015.


Inflammasome priming is similar for francisella species that differentially induce inflammasome activation.

Ghonime MG, Mitra S, Eldomany RA, Wewers MD, Gavrilin MA.

PLoS One. 2015 May 18;10(5):e0127278. doi: 10.1371/journal.pone.0127278. eCollection 2015.


Supernatants from stored red blood cell (RBC) units, but not RBC-derived microvesicles, suppress monocyte function in vitro.

Muszynski JA, Bale J, Nateri J, Nicol K, Wang Y, Wright V, Marsh CB, Gavrilin MA, Sarkar A, Wewers MD, Hall MW.

Transfusion. 2015 Aug;55(8):1937-45. doi: 10.1111/trf.13084. Epub 2015 Mar 27.


Alpha 1-antitrypsin does not inhibit human monocyte caspase-1.

Rahman MA, Mitra S, Sarkar A, Wewers MD.

PLoS One. 2015 Feb 6;10(2):e0117330. doi: 10.1371/journal.pone.0117330. eCollection 2015.


Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation.

Cardone M, Dzutsev AK, Li H, Riteau N, Gerosa F, Shenderov K, Winkler-Pickett R, Provezza L, Riboldi E, Leighty RM, Orr SJ, Steinhagen F, Wewers MD, Sher A, Anderson SK, Goldszmid R, McVicar DW, Lyakh L, Trinchieri G.

PLoS One. 2014 Dec 4;9(12):e114516. doi: 10.1371/journal.pone.0114516. eCollection 2014.


Virulent Type A Francisella tularensis actively suppresses cytokine responses in human monocytes.

Gillette DD, Curry HM, Cremer T, Ravneberg D, Fatehchand K, Shah PA, Wewers MD, Schlesinger LS, Butchar JP, Tridandapani S, Gavrilin MA.

Front Cell Infect Microbiol. 2014 Apr 10;4:45. doi: 10.3389/fcimb.2014.00045. eCollection 2014.

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