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A difficulty with the DIFFMASK score is the difficult statistics - a reply.

Lundstrøm LH, Rosenstock CV, Wetterslev J, Nørskov AK.

Anaesthesia. 2019 Oct;74(10):1338. doi: 10.1111/anae.14792. No abstract available.


Outcomes of Prophylactic Pantoprazole in Adult Intensive Care Unit Patients Receiving Dialysis: Results of a Randomized Trial.

Schefold JC, Krag M, Marker S, Perner A, Wetterslev J, Wise MP, Borthwick M, Bendel S, Keus F, Guttormsen AB, Lange T, Møller MH; the SUP-ICU investigators.

Am J Nephrol. 2019 Sep 3:1-8. doi: 10.1159/000502732. [Epub ahead of print]


Time to onset of gastrointestinal bleeding in the SUP-ICU trial: A pre-planned substudy.

Granholm A, Lange T, Anthon CT, Marker S, Krag M, Meyhoff TS, Wise MP, Borthwick M, Bendel S, Keus F, Guttormsen AB, Schefold JC, Wetterslev J, Perner A, Møller MH.

Acta Anaesthesiol Scand. 2019 Aug 23. doi: 10.1111/aas.13459. [Epub ahead of print]


Clinical Examination for the Prediction of Mortality in the Critically Ill: The Simple Intensive Care Studies-I.

Hiemstra B, Eck RJ, Wiersema R, Kaufmann T, Koster G, Scheeren TWL, Snieder H, Perner A, Pettilä V, Wetterslev J, Keus F, van der Horst ICC; SICS Study Group.

Crit Care Med. 2019 Oct;47(10):1301-1309. doi: 10.1097/CCM.0000000000003897.


Agents intervening against delirium in the intensive care unit (AID-ICU) - Protocol for a randomised placebo-controlled trial of haloperidol in patients with delirium in the ICU.

Andersen-Ranberg NC, Poulsen LM, Perner A, Wetterslev J, Estrup S, Lange T, Ebdrup BH, Hästbacka J, Morgan MPG, Citerio G, Zafrani L, Caballero J, Oxenbøll-Collet M, Weber SO, Andreasen AS, Bestle M, Pedersen HBS, Hildebrandt T, Thee C, Jensen TB, Dey N, Nielsen LG, Mathiesen O.

Acta Anaesthesiol Scand. 2019 Jul 27. doi: 10.1111/aas.13453. [Epub ahead of print]


Heterogeneity of treatment effect of stress ulcer prophylaxis in ICU patients: A secondary analysis protocol.

Granholm A, Marker S, Krag M, Zampieri FG, Thorsen-Meyer HC, Kaas-Hansen BS, van der Horst ICC, Lange T, Wetterslev J, Perner A, Møller MH.

Acta Anaesthesiol Scand. 2019 Oct;63(9):1251-1256. doi: 10.1111/aas.13432. Epub 2019 Jul 18.


Storage time of red blood cells among ICU patients with septic shock.

Rygård SL, Grønlykke L, Perner A, Winkel P, Lange T, Broksø Holst L, Johansson PI, Aneman A, Brodersen T, Laurén E, Ullum H, Wetterslev J.

Acta Anaesthesiol Scand. 2019 Jul 8. doi: 10.1111/aas.13439. [Epub ahead of print]


Pantoprazole in ICU patients at risk for gastrointestinal bleeding-1-year mortality in the SUP-ICU trial.

Marker S, Krag M, Perner A, Wetterslev J, Lange T, Wise MP, Borthwick M, Bendel S, Keus F, Guttormsen AB, Schefold JC, Rasmussen BS, Elkmann T, Bestle M, Arenkiel B, Laake JH, Kamper MK, Lång M, Pawlowicz-Dworzanska MB, Karlsson S, Liisanantti J, Dey N, Knudsen H, Granholm A, Møller MH; SUP-ICU trial investigators.

Acta Anaesthesiol Scand. 2019 Oct;63(9):1184-1190. doi: 10.1111/aas.13436. Epub 2019 Jul 19.


Conservative vs liberal fluid therapy in septic shock (CLASSIC) trial-Protocol and statistical analysis plan.

Meyhoff TS, Hjortrup PB, Møller MH, Wetterslev J, Lange T, Kjaer MN, Jonsson AB, Hjortsø CJS, Cronhjort M, Laake JH, Jakob SM, Nalos M, Pettilä V, van der Horst I, Ostermann M, Mouncey P, Rowan K, Cecconi M, Ferrer R, Malbrain MLNG, Ahlstedt C, Hoffmann S, Bestle MH, Nebrich L, Russell L, Vang M, Rasmussen ML, Sølling C, Rasmussen BS, Brøchner AC, Perner A.

Acta Anaesthesiol Scand. 2019 Oct;63(9):1262-1271. doi: 10.1111/aas.13434. Epub 2019 Jul 24.


Modification of the World Health Organization Global Guidelines for Prevention of Surgical Site Infection Is Needed.

Hedenstierna G, Meyhoff CS, Perchiazzi G, Larsson A, Wetterslev J, Rasmussen LS.

Anesthesiology. 2019 Jun 20. doi: 10.1097/ALN.0000000000002848. [Epub ahead of print] No abstract available.


Apparently conclusive meta-analyses on interventions in critical care may be inconclusive-a meta-epidemiological study.

Koster TM, Wetterslev J, Gluud C, Jakobsen JC, Kaufmann T, Eck RJ, Koster G, Hiemstra B, van der Horst ICC, Keus E.

J Clin Epidemiol. 2019 Jun 11;114:1-10. doi: 10.1016/j.jclinepi.2019.05.011. [Epub ahead of print] Review.


Power estimations for non-primary outcomes in randomised clinical trials.

Jakobsen JC, Ovesen C, Winkel P, Hilden J, Gluud C, Wetterslev J.

BMJ Open. 2019 Jun 6;9(6):e027092. doi: 10.1136/bmjopen-2018-027092.


The DIFFMASK score for predicting difficult facemask ventilation: a cohort study of 46,804 patients.

Lundstrøm LH, Rosenstock CV, Wetterslev J, Nørskov AK.

Anaesthesia. 2019 Oct;74(10):1267-1276. doi: 10.1111/anae.14701. Epub 2019 May 20.


Assessing assumptions for statistical analyses in randomised clinical trials.

Nielsen EE, Nørskov AK, Lange T, Thabane L, Wetterslev J, Beyersmann J, de Uña-Álvarez J, Torri V, Billot L, Putter H, Winkel P, Gluud C, Jakobsen JC.

BMJ Evid Based Med. 2019 Apr 4. pii: bmjebm-2019-111174. doi: 10.1136/bmjebm-2019-111174. [Epub ahead of print]


Handling Oxygenation Targets in the Intensive Care Unit (HOT-ICU)-Protocol for a randomised clinical trial comparing a lower vs a higher oxygenation target in adults with acute hypoxaemic respiratory failure.

Schjørring OL, Perner A, Wetterslev J, Lange T, Keus F, Laake JH, Okkonen M, Siegemund M, Morgan M, Thormar KM, Rasmussen BS; HOT-ICU Investigators.

Acta Anaesthesiol Scand. 2019 Aug;63(7):956-965. doi: 10.1111/aas.13356. Epub 2019 Mar 18. Review.


Pantoprazole prophylaxis in ICU patients with high severity of disease: a post hoc analysis of the placebo-controlled SUP-ICU trial.

Marker S, Perner A, Wetterslev J, Krag M, Lange T, Wise MP, Borthwick M, Bendel S, Keus F, Guttormsen AB, Schefold JC, Møller MH; SUP-ICU investigators.

Intensive Care Med. 2019 May;45(5):609-618. doi: 10.1007/s00134-019-05589-y. Epub 2019 Mar 12.


Low vs high hemoglobin trigger for transfusion in vascular surgery: a randomized clinical feasibility trial.

Møller A, Nielsen HB, Wetterslev J, Pedersen OB, Hellemann D, Winkel P, Marcussen KV, Ramsing BGU, Mortensen A, Jakobsen JC, Shahidi S.

Blood. 2019 Jun 20;133(25):2639-2650. doi: 10.1182/blood-2018-10-877530. Epub 2019 Mar 11.


Pharmacological interventions for prevention and management of delirium in intensive care patients: a systematic overview of reviews and meta-analyses.

Barbateskovic M, Krauss SR, Collet MO, Larsen LK, Jakobsen JC, Perner A, Wetterslev J.

BMJ Open. 2019 Feb 19;9(2):e024562. doi: 10.1136/bmjopen-2018-024562.


Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.

Thybo KH, Hägi-Pedersen D, Dahl JB, Wetterslev J, Nersesjan M, Jakobsen JC, Pedersen NA, Overgaard S, Schrøder HM, Schmidt H, Bjørck JG, Skovmand K, Frederiksen R, Buus-Nielsen M, Sørensen CV, Kruuse LS, Lindholm P, Mathiesen O.

JAMA. 2019 Feb 12;321(6):562-571. doi: 10.1001/jama.2018.22039.

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