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Items: 1 to 20 of 86

1.

The fragile X mutation impairs homeostatic plasticity in human neurons by blocking synaptic retinoic acid signaling.

Zhang Z, Marro SG, Zhang Y, Arendt KL, Patzke C, Zhou B, Fair T, Yang N, Südhof TC, Wernig M, Chen L.

Sci Transl Med. 2018 Aug 1;10(452). pii: eaar4338. doi: 10.1126/scitranslmed.aar4338.

PMID:
30068571
2.

Profiling DNA-transcription factor interactions.

Ang CE, Wernig M.

Nat Biotechnol. 2018 Jun 6;36(6):501-502. doi: 10.1038/nbt.4161. No abstract available.

PMID:
29874211
3.

Transdifferentiation of human adult peripheral blood T cells into neurons.

Tanabe K, Ang CE, Chanda S, Olmos VH, Haag D, Levinson DF, Südhof TC, Wernig M.

Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):6470-6475. doi: 10.1073/pnas.1720273115. Epub 2018 Jun 4.

PMID:
29866841
4.

Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons.

Wapinski OL, Lee QY, Chen AC, Li R, Corces MR, Ang CE, Treutlein B, Xiang C, Baubet V, Suchy FP, Sankar V, Sim S, Quake SR, Dahmane N, Wernig M, Chang HY.

Cell Rep. 2017 Sep 26;20(13):3236-3247. doi: 10.1016/j.celrep.2017.09.011.

5.

μNeurocircuitry: Establishing in vitro models of neurocircuits with human neurons.

Fantuzzo JA, De Filippis L, McGowan H, Yang N, Ng YH, Halikere A, Liu JJ, Hart RP, Wernig M, Zahn JD, Pang ZP.

Technology (Singap World Sci). 2017 Jun;5(2):87-97. doi: 10.1142/S2339547817500054.

6.

Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.

Chanda S, Hale WD, Zhang B, Wernig M, Südhof TC.

J Neurosci. 2017 Jul 19;37(29):6816-6836. doi: 10.1523/JNEUROSCI.0125-17.2017. Epub 2017 Jun 12.

7.

The novel tool of cell reprogramming for applications in molecular medicine.

Mall M, Wernig M.

J Mol Med (Berl). 2017 Jul;95(7):695-703. doi: 10.1007/s00109-017-1550-4. Epub 2017 Jun 8. Review.

8.

Generation of pure GABAergic neurons by transcription factor programming.

Yang N, Chanda S, Marro S, Ng YH, Janas JA, Haag D, Ang CE, Tang Y, Flores Q, Mall M, Wapinski O, Li M, Ahlenius H, Rubenstein JL, Chang HY, Buylla AA, Südhof TC, Wernig M.

Nat Methods. 2017 Jun;14(6):621-628. doi: 10.1038/nmeth.4291. Epub 2017 May 15.

9.

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model.

Rivetti di Val Cervo P, Romanov RA, Spigolon G, Masini D, Martín-Montañez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng YH, Sánchez SP, Linnarsson S, Wernig M, Harkany T, Fisone G, Arenas E.

Nat Biotechnol. 2017 May;35(5):444-452. doi: 10.1038/nbt.3835. Epub 2017 Apr 10.

PMID:
28398344
10.

Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates.

Mall M, Kareta MS, Chanda S, Ahlenius H, Perotti N, Zhou B, Grieder SD, Ge X, Drake S, Euong Ang C, Walker BM, Vierbuchen T, Fuentes DR, Brennecke P, Nitta KR, Jolma A, Steinmetz LM, Taipale J, Südhof TC, Wernig M.

Nature. 2017 Apr 13;544(7649):245-249. doi: 10.1038/nature21722. Epub 2017 Apr 5.

PMID:
28379941
11.

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons.

Chuang W, Sharma A, Shukla P, Li G, Mall M, Rajarajan K, Abilez OJ, Hamaguchi R, Wu JC, Wernig M, Wu SM.

Sci Rep. 2017 Mar 22;7:44840. doi: 10.1038/srep44840.

12.

ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion.

Huang YA, Zhou B, Wernig M, Südhof TC.

Cell. 2017 Jan 26;168(3):427-441.e21. doi: 10.1016/j.cell.2016.12.044. Epub 2017 Jan 19.

13.

Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.

Chao MP, Gentles AJ, Chatterjee S, Lan F, Reinisch A, Corces MR, Xavy S, Shen J, Haag D, Chanda S, Sinha R, Morganti RM, Nishimura T, Ameen M, Wu H, Wernig M, Wu JC, Majeti R.

Cell Stem Cell. 2017 Mar 2;20(3):329-344.e7. doi: 10.1016/j.stem.2016.11.018. Epub 2017 Jan 12.

14.

Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease.

Osorio MJ, Rowitch DH, Tesar P, Wernig M, Windrem MS, Goldman SA.

Stem Cells. 2017 Feb;35(2):311-315. doi: 10.1002/stem.2530. Epub 2016 Nov 23. Review.

15.

FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice.

Ahlenius H, Chanda S, Webb AE, Yousif I, Karmazin J, Prusiner SB, Brunet A, Südhof TC, Wernig M.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8514-9. doi: 10.1073/pnas.1607079113. Epub 2016 Jul 11.

16.

Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq.

Treutlein B, Lee QY, Camp JG, Mall M, Koh W, Shariati SA, Sim S, Neff NF, Skotheim JM, Wernig M, Quake SR.

Nature. 2016 Jun 16;534(7607):391-5. doi: 10.1038/nature18323. Epub 2016 Jun 8.

17.

Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation.

Patzke C, Acuna C, Giam LR, Wernig M, Südhof TC.

J Exp Med. 2016 Apr 4;213(4):499-515. doi: 10.1084/jem.20150951. Epub 2016 Mar 21.

18.

Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds.

Carlson AL, Bennett NK, Francis NL, Halikere A, Clarke S, Moore JC, Hart RP, Paradiso K, Wernig M, Kohn J, Pang ZP, Moghe PV.

Nat Commun. 2016 Mar 17;7:10862. doi: 10.1038/ncomms10862.

19.

Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons.

Yi F, Danko T, Botelho SC, Patzke C, Pak C, Wernig M, Südhof TC.

Science. 2016 May 6;352(6286):aaf2669. doi: 10.1126/science.aaf2669. Epub 2016 Mar 10.

20.

In Vivo Reprogramming for Brain and Spinal Cord Repair.

Chen G, Wernig M, Berninger B, Nakafuku M, Parmar M, Zhang CL.

eNeuro. 2015 Nov 9;2(5). pii: ENEURO.0106-15.2015. doi: 10.1523/ENEURO.0106-15.2015. eCollection 2015 Sep-Oct. Review.

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