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Items: 1 to 20 of 116


Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion.

Rutkowski TP, Purcell RH, Pollak RM, Grewenow SM, Gafford GM, Malone T, Khan UA, Schroeder JP, Epstein MP, Bassell GJ, Warren ST, Weinshenker D, Caspary T, Mulle JG.

Mol Psychiatry. 2019 Apr 11. doi: 10.1038/s41380-019-0413-5. [Epub ahead of print]


Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens.

Manvich DF, Petko AK, Branco RC, Foster SL, Porter-Stransky KA, Stout KA, Newman AH, Miller GW, Paladini CA, Weinshenker D.

Neuropsychopharmacology. 2019 Mar 16. doi: 10.1038/s41386-019-0371-2. [Epub ahead of print]


Chronic adolescent stress sex-specifically alters the hippocampal transcriptome in adulthood.

Rowson SA, Bekhbat M, Kelly SD, Binder EB, Hyer MM, Shaw G, Bent MA, Hodes G, Tharp G, Weinshenker D, Qin Z, Neigh GN.

Neuropsychopharmacology. 2019 Jun;44(7):1207-1215. doi: 10.1038/s41386-019-0321-z. Epub 2019 Jan 23.


Noradrenergic Transmission at Alpha1-Adrenergic Receptors in the Ventral Periaqueductal Gray Modulates Arousal.

Porter-Stransky KA, Centanni SW, Karne SL, Odil LM, Fekir S, Wong JC, Jerome C, Mitchell HA, Escayg A, Pedersen NP, Winder DG, Mitrano DA, Weinshenker D.

Biol Psychiatry. 2019 Feb 1;85(3):237-247. doi: 10.1016/j.biopsych.2018.07.027. Epub 2018 Aug 17.


Locomotor sensitization to cocaine in adolescent and adult female Wistar rats.

Rowson SA, Foster SL, Weinshenker D, Neigh GN.

Behav Brain Res. 2018 Sep 3;349:158-162. doi: 10.1016/j.bbr.2018.04.035. Epub 2018 Apr 25.


The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice.

Manvich DF, Webster KA, Foster SL, Farrell MS, Ritchie JC, Porter JH, Weinshenker D.

Sci Rep. 2018 Mar 1;8(1):3840. doi: 10.1038/s41598-018-22116-z.


Long Road to Ruin: Noradrenergic Dysfunction in Neurodegenerative Disease.

Weinshenker D.

Trends Neurosci. 2018 Apr;41(4):211-223. doi: 10.1016/j.tins.2018.01.010. Epub 2018 Feb 20. Review.


Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.

Chalermpalanupap T, Schroeder JP, Rorabaugh JM, Liles LC, Lah JJ, Levey AI, Weinshenker D.

J Neurosci. 2018 Jan 3;38(1):74-92. doi: 10.1523/JNEUROSCI.1483-17.2017. Epub 2017 Nov 13.


Effects of disulfiram on choice behavior in a rodent gambling task: association with catecholamine levels.

Di Ciano P, Manvich DF, Pushparaj A, Gappasov A, Hess EJ, Weinshenker D, Le Foll B.

Psychopharmacology (Berl). 2018 Jan;235(1):23-35. doi: 10.1007/s00213-017-4744-0. Epub 2017 Oct 30.


Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer's disease.

Rorabaugh JM, Chalermpalanupap T, Botz-Zapp CA, Fu VM, Lembeck NA, Cohen RM, Weinshenker D.

Brain. 2017 Nov 1;140(11):3023-3038. doi: 10.1093/brain/awx232.


Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus.

Chalermpalanupap T, Weinshenker D, Rorabaugh JM.

Neural Plast. 2017;2017:7829507. doi: 10.1155/2017/7829507. Epub 2017 Sep 5. Review.


LSD1 protects against hippocampal and cortical neurodegeneration.

Christopher MA, Myrick DA, Barwick BG, Engstrom AK, Porter-Stransky KA, Boss JM, Weinshenker D, Levey AI, Katz DJ.

Nat Commun. 2017 Oct 9;8(1):805. doi: 10.1038/s41467-017-00922-9.


GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant.

Giddens MM, Wong JC, Schroeder JP, Farrow EG, Smith BM, Owino S, Soden SE, Meyer RC, Saunders C, LePichon JB, Weinshenker D, Escayg A, Hall RA.

Neurobiol Dis. 2017 Oct;106:181-190. doi: 10.1016/j.nbd.2017.07.006. Epub 2017 Jul 6.


Norepinephrine regulates cocaine-primed reinstatement via α1-adrenergic receptors in the medial prefrontal cortex.

Schmidt KT, Schroeder JP, Foster SL, Squires K, Smith BM, Pitts EG, Epstein MP, Weinshenker D.

Neuropharmacology. 2017 Jun;119:134-140. doi: 10.1016/j.neuropharm.2017.04.005. Epub 2017 Apr 6.


Arresting the Development of Addiction: The Role of β-Arrestin 2 in Drug Abuse.

Porter-Stransky KA, Weinshenker D.

J Pharmacol Exp Ther. 2017 Jun;361(3):341-348. doi: 10.1124/jpet.117.240622. Epub 2017 Mar 16. Review.


Noradrenergic regulation of plasticity marker expression in the adult rodent piriform cortex.

Vadodaria KC, Yanpallewar SU, Vadhvani M, Toshniwal D, Liles LC, Rommelfanger KS, Weinshenker D, Vaidya VA.

Neurosci Lett. 2017 Mar 22;644:76-82. doi: 10.1016/j.neulet.2017.02.060. Epub 2017 Feb 23.


Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders.

Rutkowski TP, Schroeder JP, Gafford GM, Warren ST, Weinshenker D, Caspary T, Mulle JG.

J Neurosci Res. 2017 May;95(5):1144-1160. doi: 10.1002/jnr.23970. Epub 2016 Nov 8. Review.


Altered motility of plaque-associated microglia in a model of Alzheimer's disease.

Gyoneva S, Swanger SA, Zhang J, Weinshenker D, Traynelis SF.

Neuroscience. 2016 Aug 25;330:410-20. doi: 10.1016/j.neuroscience.2016.05.061. Epub 2016 Jun 7.


Bacterial Adrenergic Sensors Regulate Virulence of Enteric Pathogens in the Gut.

Moreira CG, Russell R, Mishra AA, Narayanan S, Ritchie JM, Waldor MK, Curtis MM, Winter SE, Weinshenker D, Sperandio V.

MBio. 2016 Jun 7;7(3). pii: e00826-16. doi: 10.1128/mBio.00826-16.


Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice.

Cubells JF, Schroeder JP, Barrie ES, Manvich DF, Sadee W, Berg T, Mercer K, Stowe TA, Liles LC, Squires KE, Mezher A, Curtin P, Perdomo DL, Szot P, Weinshenker D.

PLoS One. 2016 May 5;11(5):e0154864. doi: 10.1371/journal.pone.0154864. eCollection 2016.

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