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Ninjurin1 Assembles into a Homomeric Protein Complex Maintained by N-Linked Glycosylation.

Bae SJ, Shin MW, Kim RH, Shin D, Son T, Wee HJ, Kim KW.

J Cell Biochem. 2017 Jan 9. doi: 10.1002/jcb.25872. [Epub ahead of print]


Disruption of Ninjurin1 Leads to Repetitive and Anxiety-Like Behaviors in Mice.

Le H, Ahn BJ, Lee HS, Shin A, Chae S, Lee SY, Shin MW, Lee EJ, Cha JH, Son T, Seo JH, Wee HJ, Lee HJ, Jang Y, Lo EH, Jeon S, Oh GT, Kim D, Kim KW.

Mol Neurobiol. 2016 Nov 5. [Epub ahead of print]


ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.

Seo JH, Park JH, Lee EJ, Vo TT, Choi H, Kim JY, Jang JK, Wee HJ, Lee HS, Jang SH, Park ZY, Jeong J, Lee KJ, Seok SH, Park JY, Lee BJ, Lee MN, Oh GT, Kim KW.

Nat Commun. 2016 Oct 6;7:12882. doi: 10.1038/ncomms12882.


AMP-activated protein kinase activator, HL156A reduces thioacetamide-induced liver fibrosis in mice and inhibits the activation of cultured hepatic stellate cells and macrophages.

Lee HS, Shin HS, Choi J, Bae SJ, Wee HJ, Son T, Seo JH, Park JH, Kim SW, Kim KW.

Int J Oncol. 2016 Oct;49(4):1407-14. doi: 10.3892/ijo.2016.3627.


Ninjurin1 regulates lipopolysaccharide-induced inflammation through direct binding.

Shin MW, Bae SJ, Wee HJ, Lee HJ, Ahn BJ, Le H, Lee EJ, Kim RH, Lee HS, Seo JH, Park JH, Kim KW.

Int J Oncol. 2016 Feb;48(2):821-8. doi: 10.3892/ijo.2015.3296.


Autoacetylation regulates differentially the roles of ARD1 variants in tumorigenesis.

Seo JH, Park JH, Lee EJ, Vo TT, Choi H, Jang JK, Wee HJ, Ahn BJ, Cha JH, Shin MW, Kim KW.

Int J Oncol. 2015 Jan;46(1):99-106. doi: 10.3892/ijo.2014.2708.


Prompt meningeal reconstruction mediated by oxygen-sensitive AKAP12 scaffolding protein after central nervous system injury.

Cha JH, Wee HJ, Seo JH, Ahn BJ, Park JH, Yang JM, Lee SW, Lee OH, Lee HJ, Gelman IH, Arai K, Lo EH, Kim KW.

Nat Commun. 2014 Sep 17;5:4952. doi: 10.1038/ncomms5952.


Nuclear translocation of hARD1 contributes to proper cell cycle progression.

Park JH, Seo JH, Wee HJ, Vo TT, Lee EJ, Choi H, Cha JH, Ahn BJ, Shin MW, Bae SJ, Kim KW.

PLoS One. 2014 Aug 18;9(8):e105185. doi: 10.1371/journal.pone.0105185.


Visfatin promotes cell and tumor growth by upregulating Notch1 in breast cancer.

Park HJ, Kim SR, Kim SS, Wee HJ, Bae MK, Ryu MH, Bae SK.

Oncotarget. 2014 Jul 15;5(13):5087-99.


Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamics.

Ahn BJ, Le H, Shin MW, Bae SJ, Lee EJ, Lee SY, Yang JH, Wee HJ, Cha JH, Seo JH, Lee HS, Lee HJ, Arai K, Lo EH, Jeon S, Oh GT, Kim WJ, Ryu JK, Suh JK, Kim KW.

J Biol Chem. 2014 Aug 8;289(32):21926-36. doi: 10.1074/jbc.M113.532358.


AKAP12 mediates barrier functions of fibrotic scars during CNS repair.

Cha JH, Wee HJ, Seo JH, Ahn BJ, Park JH, Yang JM, Lee SW, Kim EH, Lee OH, Heo JH, Lee HJ, Gelman IH, Arai K, Lo EH, Kim KW.

PLoS One. 2014 Apr 23;9(4):e94695. doi: 10.1371/journal.pone.0094695.


Ninjurin1 deficiency attenuates susceptibility of experimental autoimmune encephalomyelitis in mice.

Ahn BJ, Le H, Shin MW, Bae SJ, Lee EJ, Wee HJ, Cha JH, Lee HJ, Lee HS, Kim JH, Kim CY, Seo JH, Lo EH, Jeon S, Lee MN, Oh GT, Yin GN, Ryu JK, Suh JK, Kim KW.

J Biol Chem. 2014 Feb 7;289(6):3328-38. doi: 10.1074/jbc.M113.498212.


Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells.

Bae YH, Ryu JH, Park HJ, Kim KR, Wee HJ, Lee OH, Jang HO, Bae MK, Kim KW, Bae SK.

Korean J Physiol Pharmacol. 2013 Aug;17(4):291-7. doi: 10.4196/kjpp.2013.17.4.291.


Melatonin inhibits visfatin-induced inducible nitric oxide synthase expression and nitric oxide production in macrophages.

Kang YS, Kang YG, Park HJ, Wee HJ, Jang HO, Bae MK, Bae SK.

J Pineal Res. 2013 Oct;55(3):294-303. doi: 10.1111/jpi.12072.


The N-terminal ectodomain of Ninjurin1 liberated by MMP9 has chemotactic activity.

Ahn BJ, Le H, Shin MW, Bae SJ, Lee EJ, Wee HJ, Cha JH, Park JH, Lee HS, Lee HJ, Jung H, Park ZY, Park SH, Han BW, Seo JH, Lo EH, Kim KW.

Biochem Biophys Res Commun. 2012 Nov 30;428(4):438-44. doi: 10.1016/j.bbrc.2012.10.099.


Curcumin down-regulates visfatin expression and inhibits breast cancer cell invasion.

Kim SR, Park HJ, Bae YH, Ahn SC, Wee HJ, Yun I, Jang HO, Bae MK, Bae SK.

Endocrinology. 2012 Feb;153(2):554-63. doi: 10.1210/en.2011-1413.


Notch1 mediates visfatin-induced FGF-2 up-regulation and endothelial angiogenesis.

Bae YH, Park HJ, Kim SR, Kim JY, Kang Y, Kim JA, Wee HJ, Kageyama R, Jung JS, Bae MK, Bae SK.

Cardiovasc Res. 2011 Feb 1;89(2):436-45. doi: 10.1093/cvr/cvq276.


The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta.

Han MS, Kim HJ, Wee HJ, Lim KE, Park NR, Bae SC, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Choi JY.

J Cell Biochem. 2010 May;110(1):97-103. doi: 10.1002/jcb.22516.


Visfatin through STAT3 activation enhances IL-6 expression that promotes endothelial angiogenesis.

Kim JY, Bae YH, Bae MK, Kim SR, Park HJ, Wee HJ, Bae SK.

Biochim Biophys Acta. 2009 Nov;1793(11):1759-67. doi: 10.1016/j.bbamcr.2009.09.006.


Aspirin induces apoptosis through the blockade of IL-6-STAT3 signaling pathway in human glioblastoma A172 cells.

Kim SR, Bae MK, Kim JY, Wee HJ, Yoo MA, Bae SK.

Biochem Biophys Res Commun. 2009 Sep 18;387(2):342-7. doi: 10.1016/j.bbrc.2009.07.022.

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