Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 72

1.

Mathematical modeling of intracrine androgen metabolism in prostate cancer: Methodological aspects.

Cook SF, Fiandalo MV, Watt DS, Wu Y, Mohler JL, Bies RR.

Prostate. 2018 Jun 25. doi: 10.1002/pros.23665. [Epub ahead of print]

PMID:
29938815
2.

Inhibition of dihydrotestosterone synthesis in prostate cancer by combined frontdoor and backdoor pathway blockade.

Fiandalo MV, Stocking JJ, Pop EA, Wilton JH, Mantione KM, Li Y, Attwood KM, Azabdaftari G, Wu Y, Watt DS, Wilson EM, Mohler JL.

Oncotarget. 2018 Jan 10;9(13):11227-11242. doi: 10.18632/oncotarget.24107. eCollection 2018 Feb 16.

3.

Phenylethynyl-substituted Heterocycles Inhibit Cyclin D1 and Induce the Expression of Cyclin-dependent Kinase Inhibitor p21Wif1/Cip1 in Colorectal Cancer Cells.

Sviripa VM, Kril LM, Zhang W, Xie Y, Wyrebek P, Ponomareva L, Liu X, Yuan Y, Zhan CG, Watt DS, Liu C.

Medchemcomm. 2018;9(1):87-99. doi: 10.1039/C7MD00393E. Epub 2017 Nov 3.

PMID:
29527286
4.

Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4).

Frasinyuk MS, Zhang W, Wyrebek P, Yu T, Xu X, Sviripa VM, Bondarenko SP, Xie Y, Ngo HX, Morris AJ, Mohler JL, Fiandalo MV, Watt DS, Liu C.

Org Biomol Chem. 2017 Sep 20;15(36):7623-7629. doi: 10.1039/c7ob01584d.

PMID:
28868548
5.

Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells.

Kenlan DE, Rychahou P, Sviripa VM, Weiss HL, Liu C, Watt DS, Evers BM.

Mol Cancer Ther. 2017 May;16(5):831-837. doi: 10.1158/1535-7163.MCT-15-0634. Epub 2017 Mar 3.

6.

Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.

Burikhanov R, Hebbar N, Noothi SK, Shukla N, Sledziona J, Araujo N, Kudrimoti M, Wang QJ, Watt DS, Welch DR, Maranchie J, Harada A, Rangnekar VM.

Cell Rep. 2017 Jan 10;18(2):508-519. doi: 10.1016/j.celrep.2016.12.051.

7.

Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents.

Shrestha SK, Kril LM, Green KD, Kwiatkowski S, Sviripa VM, Nickell JR, Dwoskin LP, Watt DS, Garneau-Tsodikova S.

Bioorg Med Chem. 2017 Jan 1;25(1):58-66. doi: 10.1016/j.bmc.2016.10.009. Epub 2016 Oct 10.

8.

Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases.

Frasinyuk MS, Mrug GP, Bondarenko SP, Khilya VP, Sviripa VM, Syrotchuk OA, Zhang W, Cai X, Fiandalo MV, Mohler JL, Liu C, Watt DS.

ChemMedChem. 2016 Mar 17;11(6):600-11. doi: 10.1002/cmdc.201600008. Epub 2016 Feb 17.

9.

Synthesis of a norcantharidin-tethered guanosine: Protein phosphatase-1 inhibitors that change alternative splicing.

Kwiatkowski S, Sviripa VM, Zhang Z, Wendlandt AE, Höbartner C, Watt DS, Stamm S.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):965-968. doi: 10.1016/j.bmcl.2015.12.054. Epub 2015 Dec 18.

10.

Advanced cardiac chemical exchange saturation transfer (cardioCEST) MRI for in vivo cell tracking and metabolic imaging.

Pumphrey A, Yang Z, Ye S, Powell DK, Thalman S, Watt DS, Abdel-Latif A, Unrine J, Thompson K, Fornwalt B, Ferrauto G, Vandsburger M.

NMR Biomed. 2016 Jan;29(1):74-83. doi: 10.1002/nbm.3451.

11.

Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin.

Sviripa VM, Burikhanov R, Obiero JM, Yuan Y, Nickell JR, Dwoskin LP, Zhan CG, Liu C, Tsodikov OV, Rangnekar VM, Watt DS.

Org Biomol Chem. 2016 Jan 7;14(1):74-84. doi: 10.1039/c5ob01980j.

12.

Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents.

Frasinyuk MS, Mrug GP, Bondarenko SP, Sviripa VM, Zhang W, Cai X, Fiandalo MV, Mohler JL, Liu C, Watt DS.

Org Biomol Chem. 2015 Dec 14;13(46):11292-301. doi: 10.1039/c5ob01828e. Epub 2015 Sep 29.

13.

Multifaceted roles for thymine DNA glycosylase in embryonic development and human carcinogenesis.

Xu X, Watt DS, Liu C.

Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):82-9. doi: 10.1093/abbs/gmv083. Epub 2015 Sep 14. Review.

14.

N-Aryl benzenesulfonamide inhibitors of [3H]-thymidine incorporation and β-catenin signaling in human hepatocyte-derived Huh-7 carcinoma cells.

Kril LM, Vilchez V, Jiang J, Turcios L, Chen C, Sviripa VM, Zhang W, Liu C, Spear B, Watt DS, Gedaly R.

Bioorg Med Chem Lett. 2015 Sep 15;25(18):3897-9. doi: 10.1016/j.bmcl.2015.07.040. Epub 2015 Jul 26.

15.

Development of 6H-Chromeno[3,4-c]pyrido[3',2':4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 Secretagogues.

Frasinyuk MS, Bondarenko SP, Sviripa VM, Burikhanov R, Rangnekar VM, Liu C, Watt DS.

Tetrahedron Lett. 2015 Jun 3;56(23):3382-3384.

16.

Analysis of trans-2,6-difluoro-4'-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite identification and pharmacokinetics.

Yeo SC, Sviripa VM, Huang M, Kril L, Watt DS, Liu C, Lin HS.

Anal Bioanal Chem. 2015 Sep;407(24):7319-32. doi: 10.1007/s00216-015-8893-x. Epub 2015 Jul 31.

PMID:
26229026
17.

Tritium-labeled (E,E)-2,5-bis(4'-hydroxy-3'-carboxystyryl)benzene as a probe for β-amyloid fibrils.

Matveev SV, Kwiatkowski S, Sviripa VM, Fazio RC, Watt DS, LeVine H 3rd.

Bioorg Med Chem Lett. 2014 Dec 1;24(23):5534-6. doi: 10.1016/j.bmcl.2014.09.075. Epub 2014 Oct 6.

18.

Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals.

Frasinyuk MS, Bondarenko SP, Khilya VP, Liu C, Watt DS, Sviripa VM.

Org Biomol Chem. 2015 Jan 28;13(4):1053-67. doi: 10.1039/c4ob02137a. Epub 2014 Nov 21.

19.

Application of the 4D fingerprint method with a robust scoring function for scaffold-hopping and drug repurposing strategies.

Hamza A, Wagner JM, Wei NN, Kwiatkowski S, Zhan CG, Watt DS, Korotkov KV.

J Chem Inf Model. 2014 Oct 27;54(10):2834-45. doi: 10.1021/ci5003872. Epub 2014 Oct 7.

20.

Arylquins target vimentin to trigger Par-4 secretion for tumor cell apoptosis.

Burikhanov R, Sviripa VM, Hebbar N, Zhang W, Layton WJ, Hamza A, Zhan CG, Watt DS, Liu C, Rangnekar VM.

Nat Chem Biol. 2014 Nov;10(11):924-926. doi: 10.1038/nchembio.1631. Epub 2014 Sep 14.

Supplemental Content

Loading ...
Support Center