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Items: 1 to 20 of 114


Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population.

Hallberg P, Persson M, Axelsson T, Cavalli M, Norling P, Johansson HE, Yue QY, Magnusson PK, Wadelius C, Eriksson N, Wadelius M.

Pharmacogenomics. 2017 Feb;18(3):201-213. doi: 10.2217/pgs-2016-0184. Epub 2017 Jan 13.


PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c.

Pan G, Ameur A, Enroth S, Bysani M, Nord H, Cavalli M, Essand M, Gyllensten U, Wadelius C.

Nucleic Acids Res. 2017 Mar 17;45(5):2408-2422. doi: 10.1093/nar/gkw1186.


Maps of context-dependent putative regulatory regions and genomic signal interactions.

Diamanti K, Umer HM, Kruczyk M, Dąbrowski MJ, Cavalli M, Wadelius C, Komorowski J.

Nucleic Acids Res. 2016 Nov 2;44(19):9110-9120. Epub 2016 Sep 12.


Genetic prevention of hepatitis C virus-induced liver fibrosis by allele-specific downregulation of MERTK.

Cavalli M, Pan G, Nord H, Wallén Arzt E, Wallerman O, Wadelius C.

Hepatol Res. 2017 Jul;47(8):826-830. doi: 10.1111/hepr.12810. Epub 2016 Sep 29.


Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy.

Eriksson N, Wallentin L, Berglund L, Axelsson T, Connolly S, Eikelboom J, Ezekowitz M, Oldgren J, Paré G, Reilly P, Siegbahn A, Syvanen AC, Wadelius C, Yusuf S, Wadelius M.

Pharmacogenomics. 2016 Aug;17(13):1425-39. doi: 10.2217/pgs-2016-0061. Epub 2016 Aug 4.


A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers.

Umer HM, Cavalli M, Dabrowski MJ, Diamanti K, Kruczyk M, Pan G, Komorowski J, Wadelius C.

Hum Mutat. 2016 Sep;37(9):904-13. doi: 10.1002/humu.23014. Epub 2016 Jun 2.


Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals.

Cavalli M, Pan G, Nord H, Wallén Arzt E, Wallerman O, Wadelius C.

Genomics. 2016 Jun;107(6):248-54. doi: 10.1016/j.ygeno.2016.04.006. Epub 2016 Apr 26.


Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression.

Cavalli M, Pan G, Nord H, Wallerman O, Wallén Arzt E, Berggren O, Elvers I, Eloranta ML, Rönnblom L, Lindblad Toh K, Wadelius C.

Hum Genet. 2016 May;135(5):485-97. doi: 10.1007/s00439-016-1654-x. Epub 2016 Mar 18.


Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose.

Cavalli M, Pan G, Nord H, Eriksson N, Wadelius C, Wadelius M.

Pharmacogenomics. 2016 Aug;17(12):1305-14. doi: 10.2217/pgs-2015-0013. Epub 2016 Feb 5.


Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels.

Cavalli M, Pan G, Nord H, Wadelius C.

Lipids Health Dis. 2016 Jan 27;15:18. doi: 10.1186/s12944-016-0183-x.


lobChIP: from cells to sequencing ready ChIP libraries in a single day.

Wallerman O, Nord H, Bysani M, Borghini L, Wadelius C.

Epigenetics Chromatin. 2015 Jul 21;8:25. doi: 10.1186/s13072-015-0017-5. eCollection 2015.


Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells.

Kruczyk M, Przanowski P, Dabrowski M, Swiatek-Machado K, Mieczkowski J, Wallerman O, Ronowicz A, Piotrowski A, Wadelius C, Kaminska B, Komorowski J.

Biochim Biophys Acta. 2014 Nov;1839(11):1341-50. doi: 10.1016/j.bbagrm.2014.07.010. Epub 2014 Aug 8.


Nucleosome regulatory dynamics in response to TGFβ.

Enroth S, Andersson R, Bysani M, Wallerman O, Termén S, Tuch BB, De La Vega FM, Heldin CH, Moustakas A, Komorowski J, Wadelius C.

Nucleic Acids Res. 2014 Jun;42(11):6921-34. doi: 10.1093/nar/gku326. Epub 2014 Apr 25.


ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer.

Bysani M, Wallerman O, Bornelöv S, Zatloukal K, Komorowski J, Wadelius C.

BMC Med Genomics. 2013 Nov 8;6:50. doi: 10.1186/1755-8794-6-50.


Genetic determinants of dabigatran plasma levels and their relation to bleeding.

Paré G, Eriksson N, Lehr T, Connolly S, Eikelboom J, Ezekowitz MD, Axelsson T, Haertter S, Oldgren J, Reilly P, Siegbahn A, Syvanen AC, Wadelius C, Wadelius M, Zimdahl-Gelling H, Yusuf S, Wallentin L.

Circulation. 2013 Apr 2;127(13):1404-12. doi: 10.1161/CIRCULATIONAHA.112.001233. Epub 2013 Mar 6.


A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements.

Enroth S, Andersson CR, Andersson R, Wadelius C, Gustafsson MG, Komorowski J.

Algorithms Mol Biol. 2012 Jan 16;7(1):2. doi: 10.1186/1748-7188-7-2.


Combinations of histone modifications mark exon inclusion levels.

Enroth S, Bornelöv S, Wadelius C, Komorowski J.

PLoS One. 2012;7(1):e29911. doi: 10.1371/journal.pone.0029911. Epub 2012 Jan 5.


Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa.

Enroth S, Rada-Iglesisas A, Andersson R, Wallerman O, Wanders A, Påhlman L, Komorowski J, Wadelius C.

BMC Cancer. 2011 Oct 19;11:450. doi: 10.1186/1471-2407-11-450.

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