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Items: 1 to 20 of 310

1.

Silencing KRAS Overexpression in Cadmium-Transformed Prostate Epithelial Cells Mitigates Malignant Phenotype.

Ngalame NN, Waalkes MP, Tokar EJ.

Chem Res Toxicol. 2016 Sep 19;29(9):1458-67. doi: 10.1021/acs.chemrestox.6b00137.

PMID:
27510461
2.

Mitigation of arsenic-induced acquired cancer phenotype in prostate cancer stem cells by miR-143 restoration.

Ngalame NN, Makia NL, Waalkes MP, Tokar EJ.

Toxicol Appl Pharmacol. 2016 Dec 1;312:11-18. doi: 10.1016/j.taap.2015.12.013.

PMID:
26721309
3.

Arsenic and Environmental Health: State of the Science and Future Research Opportunities.

Carlin DJ, Naujokas MF, Bradham KD, Cowden J, Heacock M, Henry HF, Lee JS, Thomas DJ, Thompson C, Tokar EJ, Waalkes MP, Birnbaum LS, Suk WA.

Environ Health Perspect. 2016 Jul;124(7):890-9. doi: 10.1289/ehp.1510209.

4.

Nitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor Cells.

Sharma NK, Kumar A, Kumari A, Tokar EJ, Waalkes MP, Bortner CD, Williams J, Ehrenshaft M, Mason RP, Sinha BK.

PLoS One. 2015 Nov 5;10(11):e0141897. doi: 10.1371/journal.pone.0141897.

5.

Chronic cadmium exposure in rats produces pancreatic impairment and insulin resistance in multiple peripheral tissues.

Treviño S, Waalkes MP, Flores Hernández JA, León-Chavez BA, Aguilar-Alonso P, Brambila E.

Arch Biochem Biophys. 2015 Oct 1;583:27-35. doi: 10.1016/j.abb.2015.07.010.

PMID:
26253262
6.

Differential DNA methylation profile of key genes in malignant prostate epithelial cells transformed by inorganic arsenic or cadmium.

Pelch KE, Tokar EJ, Merrick BA, Waalkes MP.

Toxicol Appl Pharmacol. 2015 Aug 1;286(3):159-67. doi: 10.1016/j.taap.2015.04.011.

7.

Chronic inorganic arsenic exposure in vitro induces a cancer cell phenotype in human peripheral lung epithelial cells.

Person RJ, Ngalame NN, Makia NL, Bell MW, Waalkes MP, Tokar EJ.

Toxicol Appl Pharmacol. 2015 Jul 1;286(1):36-43. doi: 10.1016/j.taap.2015.03.014.

8.

Macrophage solubilization and cytotoxicity of indium-containing particles as in vitro correlates to pulmonary toxicity in vivo.

Gwinn WM, Qu W, Bousquet RW, Price H, Shines CJ, Taylor GJ, Waalkes MP, Morgan DL.

Toxicol Sci. 2015 Mar;144(1):17-26. doi: 10.1093/toxsci/kfu273.

9.

Metallothionein blocks oxidative DNA damage induced by acute inorganic arsenic exposure.

Qu W, Waalkes MP.

Toxicol Appl Pharmacol. 2015 Feb 1;282(3):267-74. doi: 10.1016/j.taap.2014.11.014.

10.

Cadmium and proliferation in human uterine leiomyoma cells: evidence of a role for EGFR/MAPK pathways but not classical estrogen receptor pathways.

Gao X, Yu L, Moore AB, Kissling GE, Waalkes MP, Dixon D.

Environ Health Perspect. 2015 Apr;123(4):331-6. doi: 10.1289/ehp.1408234.

11.

Silencing KRAS overexpression in arsenic-transformed prostate epithelial and stem cells partially mitigates malignant phenotype.

Ngalame NN, Tokar EJ, Person RJ, Waalkes MP.

Toxicol Sci. 2014 Dec;142(2):489-96. doi: 10.1093/toxsci/kfu201.

12.

Response to letter to the editor by Cohen et al. (2014) "Re: Waalkes et al.: Lung tumors in mice induced by "whole-life" inorganic arsenic exposure at human-relevant doses, Arch Toxicol, 2014".

Waalkes MP, Qu W, Tokar EJ, Kissling GE, Dixon D.

Arch Toxicol. 2014 Nov;88(11):2063-5. doi: 10.1007/s00204-014-1369-5. No abstract available.

13.

Lung tumors in mice induced by "whole-life" inorganic arsenic exposure at human-relevant doses.

Waalkes MP, Qu W, Tokar EJ, Kissling GE, Dixon D.

Arch Toxicol. 2014 Aug;88(8):1619-29. doi: 10.1007/s00204-014-1305-8.

14.

Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic.

Ngalame NN, Tokar EJ, Person RJ, Xu Y, Waalkes MP.

Toxicol Sci. 2014 Apr;138(2):268-77. doi: 10.1093/toxsci/kfu002.

15.

Methylarsonous acid causes oxidative DNA damage in cells independent of the ability to biomethylate inorganic arsenic.

Tokar EJ, Kojima C, Waalkes MP.

Arch Toxicol. 2014 Feb;88(2):249-61. doi: 10.1007/s00204-013-1141-2.

16.

Arsenic-induced cancer cell phenotype in human breast epithelia is estrogen receptor-independent but involves aromatase activation.

Xu Y, Tokar EJ, Waalkes MP.

Arch Toxicol. 2014 Feb;88(2):263-74. doi: 10.1007/s00204-013-1131-4.

17.

Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation.

Severson PL, Tokar EJ, Vrba L, Waalkes MP, Futscher BW.

Epigenetics. 2013 Oct;8(10):1080-8. doi: 10.4161/epi.25926.

18.

Macrophage solubilization and cytotoxicity of indium-containing particles in vitro.

Gwinn WM, Qu W, Shines CJ, Bousquet RW, Taylor GJ, Waalkes MP, Morgan DL.

Toxicol Sci. 2013 Oct;135(2):414-24. doi: 10.1093/toxsci/kft154.

19.

Chronic cadmium exposure in vitro induces cancer cell characteristics in human lung cells.

Person RJ, Tokar EJ, Xu Y, Orihuela R, Ngalame NN, Waalkes MP.

Toxicol Appl Pharmacol. 2013 Dec 1;273(2):281-8. doi: 10.1016/j.taap.2013.06.013.

20.

Recruitment of normal stem cells to an oncogenic phenotype by noncontiguous carcinogen-transformed epithelia depends on the transforming carcinogen.

Xu Y, Tokar EJ, Person RJ, Orihuela RG, Ngalame NN, Waalkes MP.

Environ Health Perspect. 2013 Aug;121(8):944-50. doi: 10.1289/ehp.1306714.

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