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Items: 1 to 20 of 48


Use of a cocktail of spin traps for fingerprinting large range of free radicals in biological systems.

Marchand V, Charlier N, Verrax J, Buc-Calderon P, Levêque P, Gallez B.

PLoS One. 2017 Mar 2;12(3):e0172998. doi: 10.1371/journal.pone.0172998. eCollection 2017.


Chromatin remodeling regulates catalase expression during cancer cells adaptation to chronic oxidative stress.

Glorieux C, Sandoval JM, Fattaccioli A, Dejeans N, Garbe JC, Dieu M, Verrax J, Renard P, Huang P, Calderon PB.

Free Radic Biol Med. 2016 Oct;99:436-450. doi: 10.1016/j.freeradbiomed.2016.08.031. Epub 2016 Aug 31.


Overexpression of NAD(P)H:quinone oxidoreductase 1 (NQO1) and genomic gain of the NQO1 locus modulates breast cancer cell sensitivity to quinones.

Glorieux C, Sandoval JM, Dejeans N, Ameye G, Poirel HA, Verrax J, Calderon PB.

Life Sci. 2016 Jan 15;145:57-65. doi: 10.1016/j.lfs.2015.12.017. Epub 2015 Dec 10.


Binding of dihydroxynaphthyl aryl ketones to tubulin colchicine site inhibits microtubule assembly.

Gutierrez E, Benites J, Valderrama JA, Calderon PB, Verrax J, Nova E, Villanelo F, Maturana D, Escobar C, Lagos R, Monasterio O.

Biochem Biophys Res Commun. 2015 Oct 23;466(3):418-25. doi: 10.1016/j.bbrc.2015.09.041. Epub 2015 Sep 11.


Regulation of catalase expression in healthy and cancerous cells.

Glorieux C, Zamocky M, Sandoval JM, Verrax J, Calderon PB.

Free Radic Biol Med. 2015 Oct;87:84-97. doi: 10.1016/j.freeradbiomed.2015.06.017. Epub 2015 Jun 25. Review.


AICAR induces Nrf2 activation by an AMPK-independent mechanism in hepatocarcinoma cells.

Sid B, Glorieux C, Valenzuela M, Rommelaere G, Najimi M, Dejeans N, Renard P, Verrax J, Calderon PB.

Biochem Pharmacol. 2014 Sep 15;91(2):168-80. doi: 10.1016/j.bcp.2014.07.010. Epub 2014 Jul 21.


Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells.

Valenzuela M, Glorieux C, Stockis J, Sid B, Sandoval JM, Felipe KB, Kviecinski MR, Verrax J, Buc Calderon P.

Br J Cancer. 2014 Aug 26;111(5):874-82. doi: 10.1038/bjc.2014.380. Epub 2014 Jul 8.


Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway.

Glorieux C, Auquier J, Dejeans N, Sid B, Demoulin JB, Bertrand L, Verrax J, Calderon PB.

Biochem Pharmacol. 2014 May 15;89(2):217-23. doi: 10.1016/j.bcp.2014.02.025. Epub 2014 Mar 11.


p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling.

Rubio N, Verrax J, Dewaele M, Verfaillie T, Johansen T, Piette J, Agostinis P.

Free Radic Biol Med. 2014 Feb;67:292-303. doi: 10.1016/j.freeradbiomed.2013.11.010. Epub 2013 Nov 22.


Role of oxidative stress in the pathogenesis of alcohol-induced liver disease.

Sid B, Verrax J, Calderon PB.

Free Radic Res. 2013 Nov;47(11):894-904. doi: 10.3109/10715762.2013.819428. Epub 2013 Oct 4. Review.


Role of AMPK activation in oxidative cell damage: Implications for alcohol-induced liver disease.

Sid B, Verrax J, Calderon PB.

Biochem Pharmacol. 2013 Jul 15;86(2):200-9. doi: 10.1016/j.bcp.2013.05.007. Epub 2013 May 17. Review.


Antiproliferative effects of phenylaminonaphthoquinones are increased by ascorbate and associated with the appearance of a senescent phenotype in human bladder cancer cells.

Felipe KB, Benites J, Glorieux C, Sid B, Valenzuela M, Kviecinski MR, Pedrosa RC, Valderrama JA, Levêque P, Gallez B, Verrax J, Buc Calderon P.

Biochem Biophys Res Commun. 2013 Apr 19;433(4):573-8. doi: 10.1016/j.bbrc.2013.03.028. Epub 2013 Mar 22.


Sodium orthovanadate associated with pharmacological doses of ascorbate causes an increased generation of ROS in tumor cells that inhibits proliferation and triggers apoptosis.

Günther TM, Kviecinski MR, Baron CC, Felipe KB, Farias MS, da Silva FO, Bücker NC, Pich CT, Ferreira EA, Wilhelm Filho D, Verrax J, Calderon PB, Pedrosa RC.

Biochem Biophys Res Commun. 2013 Jan 18;430(3):883-8. doi: 10.1016/j.bbrc.2012.12.061. Epub 2012 Dec 19.


Biological evaluation of 3-acyl-2-arylamino-1,4-naphthoquinones as inhibitors of Hsp90 chaperoning function.

Ríos D, Benites J, Valderrama JA, Farias M, Pedrosa RC, Verrax J, Buc Calderon P.

Curr Top Med Chem. 2012;12(19):2094-102.


Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells.

De Saedeleer CJ, Copetti T, Porporato PE, Verrax J, Feron O, Sonveaux P.

PLoS One. 2012;7(10):e46571. doi: 10.1371/journal.pone.0046571. Epub 2012 Oct 17.


Gut microbiota-derived propionate reduces cancer cell proliferation in the liver.

Bindels LB, Porporato P, Dewulf EM, Verrax J, Neyrinck AM, Martin JC, Scott KP, Buc Calderon P, Feron O, Muccioli GG, Sonveaux P, Cani PD, Delzenne NM.

Br J Cancer. 2012 Oct 9;107(8):1337-44. doi: 10.1038/bjc.2012.409. Epub 2012 Sep 13.


Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif.

Beck R, Dejeans N, Glorieux C, Creton M, Delaive E, Dieu M, Raes M, Levêque P, Gallez B, Depuydt M, Collet JF, Calderon PB, Verrax J.

PLoS One. 2012;7(7):e40795. doi: 10.1371/journal.pone.0040795. Epub 2012 Jul 27.


Restoring specific lactobacilli levels decreases inflammation and muscle atrophy markers in an acute leukemia mouse model.

Bindels LB, Beck R, Schakman O, Martin JC, De Backer F, Sohet FM, Dewulf EM, Pachikian BD, Neyrinck AM, Thissen JP, Verrax J, Calderon PB, Pot B, Grangette C, Cani PD, Scott KP, Delzenne NM.

PLoS One. 2012;7(6):e37971. doi: 10.1371/journal.pone.0037971. Epub 2012 Jun 27.


Tumor reoxygenation following administration of Mitogen-Activated Protein Kinase inhibitors: a rationale for combination with radiation therapy.

Karroum O, Kengen J, Danhier P, Magat J, Mignion L, Bouzin C, Verrax J, Charette N, Starkel P, Calderon PB, Sonveaux P, Feron O, Grégoire V, Gallez B, Jordan BF.

Radiother Oncol. 2012 Oct;105(1):64-71. doi: 10.1016/j.radonc.2012.05.005. Epub 2012 Jun 8.


Inhibition of cell proliferation and migration by oxidative stress from ascorbate-driven juglone redox cycling in human bladder-derived T24 cells.

Kviecinski MR, Pedrosa RC, Felipe KB, Farias MS, Glorieux C, Valenzuela M, Sid B, Benites J, Valderrama JA, Verrax J, Buc Calderon P.

Biochem Biophys Res Commun. 2012 May 4;421(2):268-73. doi: 10.1016/j.bbrc.2012.03.150. Epub 2012 Apr 6.


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