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Items: 17


1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients.

Van Belle TL, Vanherwegen AS, Feyaerts D, De Clercq P, Verstuyf A, Korf H, Gysemans C, Mathieu C.

PLoS One. 2014 Oct 3;9(10):e109194. doi: 10.1371/journal.pone.0109194. eCollection 2014.


Oral delivery of glutamic acid decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD mice.

Robert S, Gysemans C, Takiishi T, Korf H, Spagnuolo I, Sebastiani G, Van Huynegem K, Steidler L, Caluwaerts S, Demetter P, Wasserfall CH, Atkinson MA, Dotta F, Rottiers P, Van Belle TL, Mathieu C.

Diabetes. 2014 Aug;63(8):2876-87. doi: 10.2337/db13-1236. Epub 2014 Mar 27.


1,25-Dihydroxyvitamin D3 promotes tolerogenic dendritic cells with functional migratory properties in NOD mice.

Ferreira GB, Gysemans CA, Demengeot J, da Cunha JP, Vanherwegen AS, Overbergh L, Van Belle TL, Pauwels F, Verstuyf A, Korf H, Mathieu C.

J Immunol. 2014 May 1;192(9):4210-20. doi: 10.4049/jimmunol.1302350. Epub 2014 Mar 24.


Beta-cell specific production of IL6 in conjunction with a mainly intracellular but not mainly surface viral protein causes diabetes.

Van Belle TL, Pagni PP, Liao J, Sachithanantham S, Dave A, Bel Hani A, Manenkova Y, Amirian N, Yang C, Morin B, Zhang H, Campbell IL, von Herrath MG.

J Autoimmun. 2014 Dec;55:24-32. doi: 10.1016/j.jaut.2014.02.002. Epub 2014 Feb 26.


Dietary supplementation with high doses of regular vitamin D3 safely reduces diabetes incidence in NOD mice when given early and long term.

Takiishi T, Ding L, Baeke F, Spagnuolo I, Sebastiani G, Laureys J, Verstuyf A, Carmeliet G, Dotta F, Van Belle TL, Gysemans CA, Mathieu C.

Diabetes. 2014 Jun;63(6):2026-36. doi: 10.2337/db13-1559. Epub 2014 Feb 18.


Vitamin D and diabetes: the odd couple.

Van Belle TL, Gysemans C, Mathieu C.

Trends Endocrinol Metab. 2013 Nov;24(11):561-8. doi: 10.1016/j.tem.2013.07.002. Epub 2013 Aug 21. Review.


IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells.

Van Belle TL, Dooms H, Boonefaes T, Wei XQ, Leclercq G, Grooten J.

PLoS One. 2012;7(9):e45299. doi: 10.1371/journal.pone.0045299. Epub 2012 Sep 20.


NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes.

Van Belle TL, Ling E, Haase C, Bresson D, Ursø B, von Herrath MG.

J Autoimmun. 2013 Feb;40:66-73. doi: 10.1016/j.jaut.2012.08.001. Epub 2012 Sep 1.


Low doses of anti-CD3, ciclosporin A and the vitamin D analogue, TX527, synergise to delay recurrence of autoimmune diabetes in an islet-transplanted NOD mouse model of diabetes.

Baeke F, Van Belle TL, Takiishi T, Ding L, Korf H, Laureys J, Gysemans C, Mathieu C.

Diabetologia. 2012 Oct;55(10):2723-2732. doi: 10.1007/s00125-012-2630-1. Epub 2012 Jul 3.


Interleukin-21 receptor-mediated signals control autoreactive T cell infiltration in pancreatic islets.

Van Belle TL, Nierkens S, Arens R, von Herrath MG.

Immunity. 2012 Jun 29;36(6):1060-72. doi: 10.1016/j.immuni.2012.04.005. Epub 2012 May 10.


Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice.

Takiishi T, Korf H, Van Belle TL, Robert S, Grieco FA, Caluwaerts S, Galleri L, Spagnuolo I, Steidler L, Van Huynegem K, Demetter P, Wasserfall C, Atkinson MA, Dotta F, Rottiers P, Gysemans C, Mathieu C.

J Clin Invest. 2012 May;122(5):1717-25. doi: 10.1172/JCI60530. Epub 2012 Apr 9.


Vitamin D in autoimmune, infectious and allergic diseases: a vital player?

Van Belle TL, Gysemans C, Mathieu C.

Best Pract Res Clin Endocrinol Metab. 2011 Aug;25(4):617-32. doi: 10.1016/j.beem.2011.04.009. Review.


Development of autoimmune diabetes in the absence of detectable IL-17A in a CD8-driven virally induced model.

Van Belle TL, Esplugues E, Liao J, Juntti T, Flavell RA, von Herrath MG.

J Immunol. 2011 Sep 15;187(6):2915-22. doi: 10.4049/jimmunol.1000180. Epub 2011 Aug 10.


Type 1 diabetes: etiology, immunology, and therapeutic strategies.

van Belle TL, Coppieters KT, von Herrath MG.

Physiol Rev. 2011 Jan;91(1):79-118. doi: 10.1152/physrev.00003.2010. Review.


Mouse Models for Type 1 Diabetes.

Van Belle TL, Taylor P, von Herrath MG.

Drug Discov Today Dis Models. 2009 Summer;6(2):41-45.


Pre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment.

Van Belle TL, Juntti T, Liao J, von Herrath MG.

J Autoimmun. 2010 Jun;34(4):445-52. doi: 10.1016/j.jaut.2009.11.010. Epub 2009 Dec 9.


The role of the activating receptor NKG2D in autoimmunity.

Van Belle TL, von Herrath MG.

Mol Immunol. 2009 Nov;47(1):8-11. doi: 10.1016/j.molimm.2009.02.023. Epub 2009 Mar 14. Review.


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