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Items: 1 to 20 of 100

1.

Pd(II) and Pt(II) saccharinate complexes of bis(diphenylphosphino)propane/butane: Synthesis, structure, antiproliferative activity and mechanism of action.

Yilmaz VT, Icsel C, Aygun M, Erkisa M, Ulukaya E.

Eur J Med Chem. 2018 Oct 5;158:534-547. doi: 10.1016/j.ejmech.2018.09.035. Epub 2018 Sep 14.

PMID:
30243155
2.

Palladium(ii) and platinum(ii) saccharinate complexes with bis(diphenylphosphino)methane/ethane: synthesis, S-phase arrest and ROS-mediated apoptosis in human colon cancer cells.

Icsel C, Yilmaz VT, Aygun M, Cevatemre B, Alper P, Ulukaya E.

Dalton Trans. 2018 Aug 21;47(33):11397-11410. doi: 10.1039/c8dt02389a.

PMID:
30062356
3.

Chloroquine Used in Combination with Chemotherapy Synergistically Suppresses Growth and Angiogenesis In Vitro and In Vivo.

Gurel-Gurevin E, Kiyan HT, Esener OBB, Aydinlik S, Uvez A, Ulukaya E, Dimas K, Armutak EI.

Anticancer Res. 2018 Jul;38(7):4011-4020. doi: 10.21873/anticanres.12689.

PMID:
29970525
4.

Synthesis, structures and anticancer potentials of platinum(II) saccharinate complexes of tertiary phosphines with phenyl and cyclohexyl groups targeting mitochondria and DNA.

Yilmaz VT, Icsel C, Turgut OR, Aygun M, Erkisa M, Turkdemir MH, Ulukaya E.

Eur J Med Chem. 2018 Jul 15;155:609-622. doi: 10.1016/j.ejmech.2018.06.035. Epub 2018 Jun 17.

PMID:
29920455
5.

Patient Derived Xenografts (PDX) for personalized treatment of pancreatic cancer: emerging allies in the war on a devastating cancer?

Sereti E, Karagianellou T, Kotsoni I, Magouliotis D, Kamposioras K, Ulukaya E, Sakellaridis N, Zacharoulis D, Dimas K.

J Proteomics. 2018 Sep 30;188:107-118. doi: 10.1016/j.jprot.2018.01.012. Epub 2018 Feb 14.

PMID:
29398619
6.

Quantification of DNA damage products by gas chromatography tandem mass spectrometry in lung cell lines and prevention effect of thyme antioxidants on oxidative induced DNA damage.

Aybastıer Ö, Dawbaa S, Demir C, Akgün O, Ulukaya E, Arı F.

Mutat Res. 2018 Mar;808:1-9. doi: 10.1016/j.mrfmmm.2018.01.004. Epub 2018 Jan 20.

PMID:
29366947
7.

Valproic acid, a histone deacetylase inhibitor, induces apoptosis in breast cancer stem cells.

Aztopal N, Erkisa M, Erturk E, Ulukaya E, Tokullugil AH, Ari F.

Chem Biol Interact. 2018 Jan 25;280:51-58. doi: 10.1016/j.cbi.2017.12.003. Epub 2017 Dec 7.

PMID:
29225137
8.

A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer.

Cevatemre B, Erkısa M, Aztopal N, Karakas D, Alper P, Tsimplouli C, Sereti E, Dimas K, Armutak EII, Gurevin EG, Uvez A, Mori M, Berardozzi S, Ingallina C, D'Acquarica I, Botta B, Ozpolat B, Ulukaya E.

Pharmacol Res. 2018 Mar;129:500-514. doi: 10.1016/j.phrs.2017.11.027. Epub 2017 Dec 6.

PMID:
29197639
9.

Folic acid-conjugated cationic Ag2S quantum dots for optical imaging and selective doxorubicin delivery to HeLa cells.

Duman FD, Erkisa M, Khodadust R, Ari F, Ulukaya E, Acar HY.

Nanomedicine (Lond). 2017 Oct;12(19):2319-2333. doi: 10.2217/nnm-2017-0180. Epub 2017 Sep 6.

PMID:
28875744
10.

A palladium(II)-saccharinate complex of terpyridine exerts higher anticancer potency and less toxicity than cisplatin in a mouse allograft model.

Cetin Y, Adiguzel Z, Polat HU, Akkoc T, Tas A, Cevatemre B, Celik G, Carikci B, Yilmaz VT, Ulukaya E, Acilan C.

Anticancer Drugs. 2017 Sep;28(8):898-910. doi: 10.1097/CAD.0000000000000531.

PMID:
28657910
11.

Computer-aided prediction and cytotoxicity evaluation of dithiocarbamates of 9,10-anthracenedione as new anticancer agents.

Stasevych M, Zvarych V, Lunin V, Deniz NG, Gokmen Z, Akgun O, Ulukaya E, Poroikov V, Gloriozova T, Novikov V.

SAR QSAR Environ Res. 2017 May;28(5):355-366. doi: 10.1080/1062936X.2017.1323796. Epub 2017 May 19.

PMID:
28524703
12.

Novel 1-(7-ethoxy-1-benzofuran-2-yl) substituted chalcone derivatives: Synthesis, characterization and anticancer activity.

Coskun D, Erkisa M, Ulukaya E, Coskun MF, Ari F.

Eur J Med Chem. 2017 Aug 18;136:212-222. doi: 10.1016/j.ejmech.2017.05.017. Epub 2017 May 5.

PMID:
28494257
13.

The role of cell cycle progression for the apoptosis of cancer cells induced by palladium(II)-saccharinate complexes of terpyridine.

Kacar O, Cevatemre B, Hatipoglu I, Arda N, Ulukaya E, Yilmaz VT, Acilan C.

Bioorg Med Chem. 2017 Mar 15;25(6):1770-1777. doi: 10.1016/j.bmc.2017.01.033. Epub 2017 Jan 31.

PMID:
28196706
14.

Cytotoxic and apoptotic effects of the combination of palladium (II) 5,5-diethylbarbiturate complex with bis(2-pyridylmethyl)amine and curcumin on non small lung cancer cell lines.

Tunc D, Dere E, Karakas D, Cevatemre B, Yilmaz VT, Ulukaya E.

Bioorg Med Chem. 2017 Mar 1;25(5):1717-1723. doi: 10.1016/j.bmc.2017.01.043. Epub 2017 Jan 28.

PMID:
28187956
15.

Validation data supporting the characterization of novel copper complexes as anticancer agents.

Acilan C, Cevatemre B, Adiguzel Z, Karakas D, Ulukaya E, Ribeiro N, Correia I, Pessoa JC.

Data Brief. 2016 Nov 22;9:1160-1174. doi: 10.1016/j.dib.2016.11.063. eCollection 2016 Dec.

16.

Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line.

Aydinlik S, Erkisa M, Cevatemre B, Sarimahmut M, Dere E, Ari F, Ulukaya E.

Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):49-57. doi: 10.1016/j.bbagen.2016.11.013. Epub 2016 Nov 11.

PMID:
27842219
17.

A trans-platinum(II) complex induces apoptosis in cancer stem cells of breast cancer.

Aztopal N, Karakas D, Cevatemre B, Ari F, Icsel C, Daidone MG, Ulukaya E.

Bioorg Med Chem. 2017 Jan 1;25(1):269-276. doi: 10.1016/j.bmc.2016.10.032. Epub 2016 Oct 29.

PMID:
27839660
18.

Anti-angiogenic effect of a Palladium(II)-Saccharinate Complex of Terpyridine in vitro and in vivo.

Ikitimur-Armutak EI, Gurel-Gurevin E, Kiyan HT, Aydinlik S, Yilmaz VT, Dimas K, Ulukaya E.

Microvasc Res. 2017 Jan;109:26-33. doi: 10.1016/j.mvr.2016.09.002. Epub 2016 Sep 7.

PMID:
27613574
19.

Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents.

Acilan C, Cevatemre B, Adiguzel Z, Karakas D, Ulukaya E, Ribeiro N, Correia I, Pessoa JC.

Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):218-234. doi: 10.1016/j.bbagen.2016.10.014. Epub 2016 Oct 20.

PMID:
27773706
20.

The plant-derived triterpenoid tingenin B is a potent anticancer agent due to its cytotoxic activity on cancer stem cells of breast cancer in vitro.

Cevatemre B, Botta B, Mori M, Berardozzi S, Ingallina C, Ulukaya E.

Chem Biol Interact. 2016 Dec 25;260:248-255. doi: 10.1016/j.cbi.2016.10.001. Epub 2016 Oct 5.

PMID:
27720947

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