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Items: 1 to 20 of 241

1.

Hupercumines A and B, Lycopodium Alkaloids from Huperzia cunninghamioides, Inhibiting Acetylcholinesterase.

Hirasawa Y, Mitsui C, Uchiyama N, Hakamatsuka T, Morita H.

Org Lett. 2018 Feb 12. doi: 10.1021/acs.orglett.8b00152. [Epub ahead of print]

PMID:
29431448
2.

Intraoperative Rupture of Unruptured Cerebral Aneurysm during Craniotomy: A Case Report.

Yoshiki K, Misaki K, Nambu I, Fukui I, Mohri M, Uchiyama N, Nakada M.

Case Rep Neurol. 2017 Nov 10;9(3):261-266. doi: 10.1159/000480425. eCollection 2017 Sep-Dec.

3.

Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias.

Takemoto H, Takahashi J, Hyuga S, Odaguchi H, Uchiyama N, Maruyama T, Yamashita T, Hyuga M, Oshima N, Amakura Y, Hakamatsuka T, Goda Y, Hanawa T, Kobayashi Y.

Biol Pharm Bull. 2018;41(2):247-253. doi: 10.1248/bpb.b17-00803.

4.

Physical Risk Factors of Hemorrhagic Complications Associated with Angio-Seal Closure Device Use in Neurointerventional Procedures.

Aida Y, Misaki K, Kamide T, Mohri M, Uchiyama N, Nakada M.

World Neurosurg. 2018 Jan 8. pii: S1878-8750(18)30034-2. doi: 10.1016/j.wneu.2017.12.179. [Epub ahead of print]

PMID:
29325953
5.

Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system.

Watanabe M, Sugiura Y, Sugiyama E, Narita M, Navratilova E, Kondo T, Uchiyama N, Yamanaka A, Kuzumaki N, Porreca F, Narita M.

Mol Pain. 2018 Jan-Dec;14:1744806918754934. doi: 10.1177/1744806918754934. Epub 2018 Jan 8.

PMID:
29310499
6.

[Factors for Degaussing of a Cochlear Implant Magnet in the MR Scanner].

Koganezawa T, Uchiyama N, Teshigawara M, Ogura A.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2017;73(12):1216-1223. doi: 10.6009/jjrt.2017_JSRT_73.12.1216. Japanese.

7.

Discovery of a Novel Series of Pyrazolo[1,5-a]pyrimidine-Based Phosphodiesterase 2A Inhibitors Structurally Different from N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915), for the Treatment of Cognitive Disorders.

Mikami S, Kawasaki M, Ikeda S, Negoro N, Nakamura S, Nomura I, Ashizawa T, Kokubo H, Hoffman ID, Zou H, Oki H, Uchiyama N, Hiura Y, Miyamoto M, Itou Y, Nakashima M, Iwashita H, Taniguchi T.

Chem Pharm Bull (Tokyo). 2017;65(11):1058-1077. doi: 10.1248/cpb.c17-00564.

8.

Survey on the Original Plant Species of Crude Drugs Distributed as Cynanchi Wilfordii Radix and Its Related Crude Drugs in the Korean and Chinese Markets.

Sato-Masumoto N, Uchikura T, Sugiwaki H, Yoshimura M, Masada S, Atsumi T, Watanabe M, Tanaka N, Uchiyama N, Amakura Y, Hakamatsuka T.

Biol Pharm Bull. 2017;40(10):1693-1699. doi: 10.1248/bpb.b17-00226.

9.

Natural (∆9-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB1 receptor.

Malyshevskaya O, Aritake K, Kaushik MK, Uchiyama N, Cherasse Y, Kikura-Hanajiri R, Urade Y.

Sci Rep. 2017 Sep 5;7(1):10516. doi: 10.1038/s41598-017-10447-2.

10.

The Optimal Pad Material for Fat Suppression of Breast MRI.

Teshigawara M, Ogura A, Uchiyama N, Koganezawa T.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2017;73(8):664-671. doi: 10.6009/jjrt.2017_JSRT_73.8.664. Japanese.

11.

Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders.

Mikami S, Nakamura S, Ashizawa T, Nomura I, Kawasaki M, Sasaki S, Oki H, Kokubo H, Hoffman ID, Zou H, Uchiyama N, Nakashima K, Kamiguchi N, Imada H, Suzuki N, Iwashita H, Taniguchi T.

J Med Chem. 2017 Sep 28;60(18):7677-7702. doi: 10.1021/acs.jmedchem.7b00807. Epub 2017 Sep 5.

PMID:
28796496
12.

Two flavone C-glycosides as quality control markers for the manufacturing process of ephedrine alkaloids-free Ephedra Herb extract (EFE) as a crude drug preparation.

Oshima N, Maruyama T, Yamashita T, Uchiyama N, Amakura Y, Hyuga S, Hyuga M, Nakamori S, Takemoto H, Kobayashi Y, Hakamatsuka T, Odaguchi H, Hanawa T, Goda Y.

J Nat Med. 2018 Jan;72(1):73-79. doi: 10.1007/s11418-017-1111-8. Epub 2017 Aug 3.

PMID:
28776291
13.

Chemical Analysis of Counterfeit Hepatitis C Drug Found in Japan.

Uchiyama N, Kamakura H, Masada S, Tsujimoto T, Hosoe J, Tokumoto H, Maruyama T, Goda Y, Hakamatsuka T.

Yakugaku Zasshi. 2017 Oct 1;137(10):1265-1276. doi: 10.1248/yakushi.17-00136. Epub 2017 Jul 19. Japanese.

14.

Aristeromycin and DZNeP cause growth inhibition of prostate cancer via induction of mir-26a.

Uchiyama N, Tanaka Y, Kawamoto T.

Eur J Pharmacol. 2017 Oct 5;812:138-146. doi: 10.1016/j.ejphar.2017.07.023. Epub 2017 Jul 10.

PMID:
28705714
15.

Fabry disease.

Yuasa T, Takenaka T, Higuchi K, Uchiyama N, Horizoe Y, Cyaen H, Mizukami N, Takasaki K, Kisanuki A, Miyata M, Ohishi M.

J Echocardiogr. 2017 Dec;15(4):151-157. doi: 10.1007/s12574-017-0340-x. Epub 2017 Jul 3.

PMID:
28674962
16.

2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase.

Kurasawa O, Homma M, Oguro Y, Miyazaki T, Mori K, Uchiyama N, Iwai K, Ohashi A, Hara H, Yoshida S, Cho N.

Bioorg Med Chem. 2017 Jul 15;25(14):3658-3670. doi: 10.1016/j.bmc.2017.04.044. Epub 2017 May 2.

PMID:
28533114
17.

Identification of AHCY inhibitors using novel high-throughput mass spectrometry.

Uchiyama N, Dougan DR, Lawson JD, Kimura H, Matsumoto SI, Tanaka Y, Kawamoto T.

Biochem Biophys Res Commun. 2017 Sep 9;491(1):1-7. doi: 10.1016/j.bbrc.2017.05.107. Epub 2017 May 19.

PMID:
28533090
18.

Anomalies of the Middle Cerebral Artery.

Uchiyama N.

Neurol Med Chir (Tokyo). 2017 Jun 15;57(6):261-266. doi: 10.2176/nmc.ra.2017-0043. Epub 2017 Apr 27.

19.

Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma.

Furuta T, Sabit H, Dong Y, Miyashita K, Kinoshita M, Uchiyama N, Hayashi Y, Hayashi Y, Minamoto T, Nakada M.

Oncotarget. 2017 Apr 4;8(14):22811-22824. doi: 10.18632/oncotarget.15206.

20.

A Pediatric Case of Reversible Cerebral Vasoconstriction Syndrome With Similar Radiographic Findings to Posterior Reversible Encephalopathy Syndrome.

Kamide T, Tsutsui T, Misaki K, Sano H, Mohri M, Uchiyama N, Nakada M.

Pediatr Neurol. 2017 Jun;71:73-76. doi: 10.1016/j.pediatrneurol.2017.02.008. Epub 2017 Feb 20.

PMID:
28372869

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