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Items: 1 to 20 of 233

1.

Natural (∆9-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB1 receptor.

Malyshevskaya O, Aritake K, Kaushik MK, Uchiyama N, Cherasse Y, Kikura-Hanajiri R, Urade Y.

Sci Rep. 2017 Sep 5;7(1):10516. doi: 10.1038/s41598-017-10447-2.

2.

The Optimal Pad Material for Fat Suppression of Breast MRI.

Teshigawara M, Ogura A, Uchiyama N, Koganezawa T.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2017;73(8):664-671. doi: 10.6009/jjrt.2017_JSRT_73.8.664.

3.

Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders.

Mikami S, Nakamura S, Ashizawa T, Nomura I, Kawasaki M, Sasaki S, Oki H, Kokubo H, Hoffman ID, Zou H, Uchiyama N, Nakashima K, Kamiguchi N, Imada H, Suzuki N, Iwashita H, Taniguchi T.

J Med Chem. 2017 Sep 5. doi: 10.1021/acs.jmedchem.7b00807. [Epub ahead of print]

PMID:
28796496
4.

Two flavone C-glycosides as quality control markers for the manufacturing process of ephedrine alkaloids-free Ephedra Herb extract (EFE) as a crude drug preparation.

Oshima N, Maruyama T, Yamashita T, Uchiyama N, Amakura Y, Hyuga S, Hyuga M, Nakamori S, Takemoto H, Kobayashi Y, Hakamatsuka T, Odaguchi H, Hanawa T, Goda Y.

J Nat Med. 2017 Aug 3. doi: 10.1007/s11418-017-1111-8. [Epub ahead of print]

PMID:
28776291
5.

Chemical analysis of counterfeit hepatitis C drug found in Japan.

Uchiyama N, Kamakura H, Masada S, Tsujimoto T, Hosoe J, Tokumoto H, Maruyama T, Goda Y, Hakamatsuka T.

Yakugaku Zasshi. 2017 Jul 19. doi: 10.1248/yakushi.17-00136. [Epub ahead of print]

6.

Aristeromycin and DZNeP cause growth inhibition of prostate cancer via induction of mir-26a.

Uchiyama N, Tanaka Y, Kawamoto T.

Eur J Pharmacol. 2017 Oct 5;812:138-146. doi: 10.1016/j.ejphar.2017.07.023. Epub 2017 Jul 10.

PMID:
28705714
7.

Fabry disease.

Yuasa T, Takenaka T, Higuchi K, Uchiyama N, Horizoe Y, Cyaen H, Mizukami N, Takasaki K, Kisanuki A, Miyata M, Ohishi M.

J Echocardiogr. 2017 Jul 3. doi: 10.1007/s12574-017-0340-x. [Epub ahead of print]

PMID:
28674962
8.

2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase.

Kurasawa O, Homma M, Oguro Y, Miyazaki T, Mori K, Uchiyama N, Iwai K, Ohashi A, Hara H, Yoshida S, Cho N.

Bioorg Med Chem. 2017 Jul 15;25(14):3658-3670. doi: 10.1016/j.bmc.2017.04.044. Epub 2017 May 2.

PMID:
28533114
9.

Identification of AHCY inhibitors using novel high-throughput mass spectrometry.

Uchiyama N, Dougan DR, Lawson JD, Kimura H, Matsumoto SI, Tanaka Y, Kawamoto T.

Biochem Biophys Res Commun. 2017 Sep 9;491(1):1-7. doi: 10.1016/j.bbrc.2017.05.107. Epub 2017 May 19.

PMID:
28533090
10.

Anomalies of the Middle Cerebral Artery.

Uchiyama N.

Neurol Med Chir (Tokyo). 2017 Jun 15;57(6):261-266. doi: 10.2176/nmc.ra.2017-0043. Epub 2017 Apr 27.

11.

Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma.

Furuta T, Sabit H, Dong Y, Miyashita K, Kinoshita M, Uchiyama N, Hayashi Y, Hayashi Y, Minamoto T, Nakada M.

Oncotarget. 2017 Apr 4;8(14):22811-22824. doi: 10.18632/oncotarget.15206.

12.

A Pediatric Case of Reversible Cerebral Vasoconstriction Syndrome With Similar Radiographic Findings to Posterior Reversible Encephalopathy Syndrome.

Kamide T, Tsutsui T, Misaki K, Sano H, Mohri M, Uchiyama N, Nakada M.

Pediatr Neurol. 2017 Jun;71:73-76. doi: 10.1016/j.pediatrneurol.2017.02.008. Epub 2017 Feb 20.

PMID:
28372869
14.

Inflow hemodynamics evaluated by using four-dimensional flow magnetic resonance imaging and the size ratio of unruptured cerebral aneurysms.

Futami K, Nambu I, Kitabayashi T, Sano H, Misaki K, Uchiyama N, Nakada M.

Neuroradiology. 2017 Apr;59(4):411-418. doi: 10.1007/s00234-017-1801-7. Epub 2017 Mar 7.

PMID:
28271159
15.

Long-term predictive factors of the morphology based outcome in bare platinum coiled intracranial aneurysms: Evaluation by pre- and post-contrast 3D time-of-flight MR angiography.

Ueda F, Uchiyama N, Mohri M, Misaki K, Matsui O, Kida S, Sanada J, Yoshikawa J, Aburano H, Yoshie Y, Gabata T.

Neurol Neurochir Pol. 2017 Mar - Apr;51(2):116-126. doi: 10.1016/j.pjnns.2017.01.002. Epub 2017 Jan 21.

PMID:
28256206
16.

CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.

Funnell T, Tasaki S, Oloumi A, Araki S, Kong E, Yap D, Nakayama Y, Hughes CS, Cheng SG, Tozaki H, Iwatani M, Sasaki S, Ohashi T, Miyazaki T, Morishita N, Morishita D, Ogasawara-Shimizu M, Ohori M, Nakao S, Karashima M, Sano M, Murai A, Nomura T, Uchiyama N, Kawamoto T, Hara R, Nakanishi O, Shumansky K, Rosner J, Wan A, McKinney S, Morin GB, Nakanishi A, Shah S, Toyoshiba H, Aparicio S.

Nat Commun. 2017 Feb 23;8(1):7. doi: 10.1038/s41467-016-0008-7.

17.

Concurrent cervical dural and multiple perimedullary arteriovenous fistulas presenting with subarachnoid hemorrhage: The source of bleeding was invisible at initial angiography.

Nambu I, Uchiyama N, Misaki K, Mohri M, Nakada M.

Surg Neurol Int. 2017 Jan 19;8:2. doi: 10.4103/2152-7806.198729. eCollection 2017.

18.

Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitors.

Kiryanov A, Natala S, Jones B, McBride C, Feher V, Lam B, Liu Y, Honda K, Uchiyama N, Kawamoto T, Hikichi Y, Zhang L, Hosfield D, Skene R, Zou H, Stafford J, Cao X, Ichikawa T.

Bioorg Med Chem Lett. 2017 Mar 1;27(5):1311-1315. doi: 10.1016/j.bmcl.2016.10.009. Epub 2016 Oct 15.

PMID:
28169164
19.

Delayed asymptomatic coil migrations toward different arteries after aneurysmal embolization: case report.

Kamide T, Misaki K, Nambu I, Mohri M, Uchiyama N, Nakada M.

Acta Neurochir (Wien). 2017 Mar;159(3):593-598. doi: 10.1007/s00701-017-3083-6. Epub 2017 Jan 21.

PMID:
28110403
20.

Intracranial aneurysm formation after radiotherapy for medulloblastoma.

Kamide T, Mohri M, Misaki K, Uchiyama N, Nakada M.

Surg Neurol Int. 2016 Nov 21;7(Suppl 37):S880-S882. doi: 10.4103/2152-7806.194501. eCollection 2016.

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