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Items: 1 to 20 of 51

1.

Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain.

Walters DK, Arendt BK, Tschumper RC, Wu X, Jelinek DF.

Exp Hematol. 2018 Jan;57:42-49.e1. doi: 10.1016/j.exphem.2017.09.010. Epub 2017 Oct 13.

PMID:
29030084
2.

Clonotypic Light Chain Peptides Identified for Monitoring Minimal Residual Disease in Multiple Myeloma without Bone Marrow Aspiration.

Bergen HR 3rd, Dasari S, Dispenzieri A, Mills JR, Ramirez-Alvarado M, Tschumper RC, Jelinek DF, Barnidge DR, Murray DL.

Clin Chem. 2016 Jan;62(1):243-51. doi: 10.1373/clinchem.2015.242651. Epub 2015 Oct 1.

3.

Proteomic detection of immunoglobulin light chain variable region peptides from amyloidosis patient biopsies.

Dasari S, Theis JD, Vrana JA, Meureta OM, Quint PS, Muppa P, Zenka RM, Tschumper RC, Jelinek DF, Davila JI, Sarangi V, Kurtin PJ, Dogan A.

J Proteome Res. 2015 Apr 3;14(4):1957-67. doi: 10.1021/acs.jproteome.5b00015. Epub 2015 Mar 20.

PMID:
25734799
4.

Phenotyping polyclonal kappa and lambda light chain molecular mass distributions in patient serum using mass spectrometry.

Barnidge DR, Dasari S, Ramirez-Alvarado M, Fontan A, Willrich MA, Tschumper RC, Jelinek DF, Snyder MR, Dispenzieri A, Katzmann JA, Murray DL.

J Proteome Res. 2014 Nov 7;13(11):5198-205. doi: 10.1021/pr5005967. Epub 2014 Aug 26.

PMID:
25134970
5.

Multiple myeloma dell-derived microvesicles are enriched in CD147 expression and enhance tumor cell proliferation.

Arendt BK, Walters DK, Wu X, Tschumper RC, Jelinek DF.

Oncotarget. 2014 Jul 30;5(14):5686-99.

6.

TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells.

Wu X, Blackburn PR, Tschumper RC, Ekker SC, Jelinek DF.

Blood Cancer J. 2014 May 9;4:e210. doi: 10.1038/bcj.2014.32.

7.

Monitoring M-proteins in patients with multiple myeloma using heavy-chain variable region clonotypic peptides and LC-MS/MS.

Barnidge DR, Tschumper RC, Theis JD, Snyder MR, Jelinek DF, Katzmann JA, Dispenzieri A, Murray DL.

J Proteome Res. 2014 Apr 4;13(4):1905-10. doi: 10.1021/pr5000544. Epub 2014 Mar 5.

PMID:
24552626
8.

Patients with chronic lymphocytic leukaemia and clonal deletion of both 17p13.1 and 11q22.3 have a very poor prognosis.

Greipp PT, Smoley SA, Viswanatha DS, Frederick LS, Rabe KG, Sharma RG, Slager SL, Van Dyke DL, Shanafelt TD, Tschumper RC, Zent CS.

Br J Haematol. 2013 Nov;163(3):326-33. doi: 10.1111/bjh.12534. Epub 2013 Aug 27.

9.

Genetic characterization of SF3B1 mutations in single chronic lymphocytic leukemia cells.

Wu X, Tschumper RC, Jelinek DF.

Leukemia. 2013 Nov;27(11):2264-7. doi: 10.1038/leu.2013.155. Epub 2013 May 20. No abstract available.

10.

Molecular analysis of immunoglobulin genes reveals frequent clonal relatedness in double monoclonal gammopathies.

Tschumper RC, Dispenzieri A, Abraham RS, Henderson KJ, Jelinek DF.

Blood Cancer J. 2013 Apr 19;3:e112. doi: 10.1038/bcj.2013.12.

11.

Comprehensive assessment of potential multiple myeloma immunoglobulin heavy chain V-D-J intraclonal variation using massively parallel pyrosequencing.

Tschumper RC, Asmann YW, Hossain A, Huddleston PM, Wu X, Dispenzieri A, Eckloff BW, Jelinek DF.

Oncotarget. 2012 Apr;3(4):502-13.

12.

Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: role in regulation of myeloma cell proliferation.

Arendt BK, Walters DK, Wu X, Tschumper RC, Huddleston PM, Henderson KJ, Dispenzieri A, Jelinek DF.

Leukemia. 2012 Oct;26(10):2286-96. doi: 10.1038/leu.2012.91. Epub 2012 Mar 30.

13.

Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse.

Braggio E, Kay NE, VanWier S, Tschumper RC, Smoley S, Eckel-Passow JE, Sassoon T, Barrett M, Van Dyke DL, Byrd JC, Jelinek DF, Shanafelt TD, Fonseca R.

Leukemia. 2012 Jul;26(7):1698-701. doi: 10.1038/leu.2012.14. Epub 2012 Jan 20. No abstract available.

14.

Differentiation of chronic lymphocytic leukemia B cells into immunoglobulin secreting cells decreases LEF-1 expression.

Gutierrez A Jr, Arendt BK, Tschumper RC, Kay NE, Zent CS, Jelinek DF.

PLoS One. 2011;6(10):e26056. doi: 10.1371/journal.pone.0026056. Epub 2011 Oct 6.

15.

Evidence for ongoing DNA damage in multiple myeloma cells as revealed by constitutive phosphorylation of H2AX.

Walters DK, Wu X, Tschumper RC, Arendt BK, Huddleston PM, Henderson KJ, Dispenzieri A, Jelinek DF.

Leukemia. 2011 Aug;25(8):1344-53. doi: 10.1038/leu.2011.94. Epub 2011 May 13.

16.

Selective induction of DNA repair pathways in human B cells activated by CD4+ T cells.

Wu X, Tschumper RC, Gutierrez A Jr, Mihalcik SA, Nowakowski GS, Jelinek DF.

PLoS One. 2010 Dec 16;5(12):e15549. doi: 10.1371/journal.pone.0015549.

17.

Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy.

Kay NE, Eckel-Passow JE, Braggio E, Vanwier S, Shanafelt TD, Van Dyke DL, Jelinek DF, Tschumper RC, Kipps T, Byrd JC, Fonseca R.

Cancer Genet Cytogenet. 2010 Dec;203(2):161-8. doi: 10.1016/j.cancergencyto.2010.09.003.

18.

Transcriptional and post-transcriptional mechanisms of BAFF-receptor dysregulation in human B lineage malignancies.

Mihalcik SA, Tschumper RC, Jelinek DF.

Cell Cycle. 2010 Dec 15;9(24):4884-92. Epub 2010 Dec 15.

19.

Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch.

Ding W, Knox TR, Tschumper RC, Wu W, Schwager SM, Boysen JC, Jelinek DF, Kay NE.

Blood. 2010 Oct 21;116(16):2984-93. doi: 10.1182/blood-2010-02-269894. Epub 2010 Jul 6.

20.

LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis.

Gutierrez A Jr, Tschumper RC, Wu X, Shanafelt TD, Eckel-Passow J, Huddleston PM 3rd, Slager SL, Kay NE, Jelinek DF.

Blood. 2010 Oct 21;116(16):2975-83. doi: 10.1182/blood-2010-02-269878. Epub 2010 Jul 1.

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