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Items: 1 to 20 of 194

1.

Influence of Physicochemical Properties of Lipopeptide Adjuvants on the Immune Response: A Rationale for Engineering a Potent Vaccine.

Eskandari S, Pattinson DJ, Stephenson RJ, Groves PL, Apte SH, Sedaghat B, Chandurudu S, Doolan DL, Toth I.

Chemistry. 2018 Jul 11;24(39):9892-9902. doi: 10.1002/chem.201801378. Epub 2018 Jun 19.

PMID:
29707835
2.

Bombesin/oligoarginine fusion peptides for gastrin releasing peptide receptor (GRPR) targeted gene delivery.

Begum AA, Wan Y, Toth I, Moyle PM.

Bioorg Med Chem. 2018 Jan 15;26(2):516-526. doi: 10.1016/j.bmc.2017.12.013. Epub 2017 Dec 12.

PMID:
29269254
3.

Development of New Gonadotropin-Releasing Hormone-Modified Dendrimer Platforms with Direct Antiproliferative and Gonadotropin Releasing Activity.

Varamini P, Rafiee A, Giddam AK, Mansfeld FM, Steyn F, Toth I.

J Med Chem. 2017 Oct 26;60(20):8309-8320. doi: 10.1021/acs.jmedchem.6b01771. Epub 2017 Oct 11.

PMID:
28958147
4.

Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein.

Jaberolansar N, Chappell KJ, Watterson D, Bermingham IM, Toth I, Young PR, Skwarczynski M.

Sci Rep. 2017 Sep 11;7(1):11130. doi: 10.1038/s41598-017-10415-w.

5.

Bivalent mucosal peptide vaccines administered using the LCP carrier system stimulate protective immune responses against Streptococcus pyogenes infection.

Schulze K, Ebensen T, Chandrudu S, Skwarczynski M, Toth I, Olive C, Guzman CA.

Nanomedicine. 2017 Nov;13(8):2463-2474. doi: 10.1016/j.nano.2017.08.015. Epub 2017 Sep 5.

PMID:
28887213
6.

Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells.

Wan Y, Dai W, Nevagi RJ, Toth I, Moyle PM.

Acta Biomater. 2017 Sep 1;59:257-268. doi: 10.1016/j.actbio.2017.06.032. Epub 2017 Jun 24.

PMID:
28655658
7.

New gonadotropin-releasing hormone glycolipids with direct antiproliferative activity and gonadotropin-releasing potency.

Varamini P, Mansfeld FM, Giddam AK, Steyn F, Toth I.

Int J Pharm. 2017 Apr 15;521(1-2):327-336. doi: 10.1016/j.ijpharm.2017.02.054. Epub 2017 Feb 21. No abstract available.

PMID:
28232269
8.

Comparison of Fluorinated and Nonfluorinated Lipids in Self-Adjuvanting Delivery Systems for Peptide-Based Vaccines.

Hussein WM, Mukaida S, Azmi F, Bartlett S, Olivier C, Batzloff MR, Good MF, Skwarczynski M, Toth I.

ACS Med Chem Lett. 2017 Jan 24;8(2):227-232. doi: 10.1021/acsmedchemlett.6b00453. eCollection 2017 Feb 9.

9.

Intranasal delivery of nanoparticle-based vaccines.

Marasini N, Skwarczynski M, Toth I.

Ther Deliv. 2017 Jan;8(3):151-167. doi: 10.4155/tde-2016-0068. Review.

PMID:
28145824
10.

An Overview of Structural Features of Antibacterial Glycoconjugate Vaccines That Influence Their Immunogenicity.

Khatun F, Stephenson RJ, Toth I.

Chemistry. 2017 Mar 28;23(18):4233-4254. doi: 10.1002/chem.201603599. Epub 2017 Jan 18. Review. Erratum in: Chemistry. 2017 May 5;23 (26):6458.

PMID:
28097690
11.

Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.

Wan Y, Moyle PM, Gn PZ, Toth I.

Nanomedicine (Lond). 2017 Feb;12(4):281-293. doi: 10.2217/nnm-2016-0354. Epub 2017 Jan 17.

PMID:
28093948
12.

Synthesis, Characterization and Immunological Evaluation of Self-Adjuvanting Group A Streptococcal Vaccine Candidates Bearing Various Lipidic Adjuvanting Moieties.

Fagan V, Hussein WM, Su M, Giddam AK, Batzloff MR, Good MF, Toth I, Simerska P.

Chembiochem. 2017 Mar 16;18(6):545-553. doi: 10.1002/cbic.201600639. Epub 2017 Feb 15.

PMID:
28075053
13.

Novel platform technology for modular mucosal vaccine that protects against streptococcus.

Zaman M, Ozberk V, Langshaw EL, McPhun V, Powell JL, Phillips ZN, Ho MF, Calcutt A, Batzloff MR, Toth I, Hill GR, Pandey M, Good MF.

Sci Rep. 2016 Dec 15;6:39274. doi: 10.1038/srep39274.

14.

Double adjuvanting strategy for peptide-based vaccines: trimethyl chitosan nanoparticles for lipopeptide delivery.

Marasini N, Giddam AK, Khalil ZG, Hussein WM, Capon RJ, Batzloff MR, Good MF, Toth I, Skwarczynski M.

Nanomedicine (Lond). 2016 Dec;11(24):3223-3235. Epub 2016 Nov 10.

PMID:
27830630
15.

Investigation of bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor.

Begum AA, Moyle PM, Toth I.

Bioorg Med Chem. 2016 Nov 15;24(22):5834-5841. doi: 10.1016/j.bmc.2016.09.039. Epub 2016 Sep 16.

PMID:
27670095
16.

Lipid core peptide/poly(lactic-co-glycolic acid) as a highly potent intranasal vaccine delivery system against Group A streptococcus.

Marasini N, Khalil ZG, Giddam AK, Ghaffar KA, Hussein WM, Capon RJ, Batzloff MR, Good MF, Skwarczynski M, Toth I.

Int J Pharm. 2016 Nov 20;513(1-2):410-420. doi: 10.1016/j.ijpharm.2016.09.057. Epub 2016 Sep 20.

PMID:
27659862
17.

Linear and branched polyacrylates as a delivery platform for peptide-based vaccines.

Chandrudu S, Bartlett S, Khalil ZG, Jia Z, Hussein WM, Capon RJ, Batzloff MR, Good MF, Monteiro MJ, Skwarczynski M, Toth I.

Ther Deliv. 2016 Sep;7(9):601-9. doi: 10.4155/tde-2016-0037.

PMID:
27582233
18.

Towards the Development of Synthetic Antibiotics: Designs Inspired by Natural Antimicrobial Peptides.

Azmi F, Skwarczynski M, Toth I.

Curr Med Chem. 2016;23(41):4610-4624. Review.

PMID:
27570165
19.

A semi-synthetic whole parasite vaccine designed to protect against blood stage malaria.

Giddam AK, Reiman JM, Zaman M, Skwarczynski M, Toth I, Good MF.

Acta Biomater. 2016 Oct 15;44:295-303. doi: 10.1016/j.actbio.2016.08.020. Epub 2016 Aug 17.

PMID:
27544810
20.

Evaluation of Lipopeptides as Toll-like Receptor 2 Ligands.

Hussein WM, Choi PM, Zhang C, Su M, Sierecki E, Johnston W, Fagan V, Alexandrov K, Skwarczynski M, Gambin Y, Toth I, Simerska P.

Curr Drug Deliv. 2017;14(7):935-943. doi: 10.2174/1567201813666160804114107.

PMID:
27494158

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