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Items: 1 to 20 of 137

1.

Cell-specific expression of insulin/insulin-like growth factor-I receptor hybrids in the mouse brain.

Martinez-Rachadell L, Aguilera A, Perez-Domper P, Pignatelli J, Fernandez AM, Torres-Aleman I.

Growth Horm IGF Res. 2019 Apr;45:25-30. doi: 10.1016/j.ghir.2019.02.003. Epub 2019 Feb 22.

PMID:
30825797
2.

Insulin Peptides as Mediators of the Impact of Life Style in Alzheimer's disease.

Fernandez AM, Santi A, Torres Aleman I.

Brain Plast. 2018 Dec 12;4(1):3-15. doi: 10.3233/BPL-180071. Review.

3.

A network of insulin peptides regulate glucose uptake by astrocytes: Potential new druggable targets for brain hypometabolism.

Fernandez AM, Hernandez E, Guerrero-Gomez D, Miranda-Vizuete A, Torres Aleman I.

Neuropharmacology. 2018 Jul 1;136(Pt B):216-222. doi: 10.1016/j.neuropharm.2017.08.034. Epub 2017 Aug 30. Review.

PMID:
28859884
4.

Acute exercise does not modify brain activity and memory performance in APP/PS1 mice.

Miki Stein A, Munive V, Fernandez AM, Nuñez A, Torres Aleman I.

PLoS One. 2017 May 22;12(5):e0178247. doi: 10.1371/journal.pone.0178247. eCollection 2017.

5.

A Coordinated Action of Blood-Borne and Brain Insulin-Like Growth Factor I in the Response to Traumatic Brain Injury.

Santi A, Genis L, Torres Aleman I.

Cereb Cortex. 2018 Jun 1;28(6):2007-2014. doi: 10.1093/cercor/bhx106.

PMID:
28449086
6.

A role for astrocytes in cerebellar deficits in frataxin deficiency: Protection by insulin-like growth factor I.

Franco C, Genis L, Navarro JA, Perez-Domper P, Fernandez AM, Schneuwly S, Torres Alemán I.

Mol Cell Neurosci. 2017 Apr;80:100-110. doi: 10.1016/j.mcn.2017.02.008. Epub 2017 Mar 7.

PMID:
28286293
7.

Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I.

Fernandez AM, Hernandez-Garzón E, Perez-Domper P, Perez-Alvarez A, Mederos S, Matsui T, Santi A, Trueba-Saiz A, García-Guerra L, Pose-Utrilla J, Fielitz J, Olson EN, Fernandez de la Rosa R, Garcia Garcia L, Pozo MA, Iglesias T, Araque A, Soya H, Perea G, Martin ED, Torres Aleman I.

Diabetes. 2017 Jan;66(1):64-74. doi: 10.2337/db16-0861. Epub 2016 Oct 10.

8.

Moderate exercise ameliorates dysregulated hippocampal glycometabolism and memory function in a rat model of type 2 diabetes.

Shima T, Matsui T, Jesmin S, Okamoto M, Soya M, Inoue K, Liu YF, Torres-Aleman I, McEwen BS, Soya H.

Diabetologia. 2017 Mar;60(3):597-606. doi: 10.1007/s00125-016-4164-4. Epub 2016 Dec 8.

PMID:
27928614
9.

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.

García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH.

Cell. 2016 Aug 11;166(4):867-880. doi: 10.1016/j.cell.2016.07.028.

10.

The insulin-like growth factor I receptor regulates glucose transport by astrocytes.

Hernandez-Garzón E, Fernandez AM, Perez-Alvarez A, Genis L, Bascuñana P, Fernandez de la Rosa R, Delgado M, Angel Pozo M, Moreno E, McCormick PJ, Santi A, Trueba-Saiz A, Garcia-Caceres C, Tschöp MH, Araque A, Martin ED, Torres Aleman I.

Glia. 2016 Nov;64(11):1962-71. doi: 10.1002/glia.23035. Epub 2016 Jul 27.

PMID:
27462832
11.

Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation.

Diez H, Benitez MJ, Fernandez S, Torres-Aleman I, Garrido JJ, Wandosell F.

Biochim Biophys Acta. 2016 Nov;1863(11):2574-2583. doi: 10.1016/j.bbamcr.2016.07.002. Epub 2016 Jul 12.

12.

A Concerted Action Of Estradiol And Insulin Like Growth Factor I Underlies Sex Differences In Mood Regulation By Exercise.

Munive V, Santi A, Torres-Aleman I.

Sci Rep. 2016 May 12;6:25969. doi: 10.1038/srep25969.

13.

Exercise and cerebrovascular plasticity.

Nishijima T, Torres-Aleman I, Soya H.

Prog Brain Res. 2016;225:243-68. doi: 10.1016/bs.pbr.2016.03.010. Epub 2016 Apr 11. Review.

PMID:
27130419
14.

Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-β-Induced Neuronal Death.

Fernandez AM, Hervas R, Dominguez-Fraile M, Garrido VN, Gomez-Gutierrez P, Vega M, Vitorica J, Perez JJ, Torres Aleman I.

J Alzheimers Dis. 2016 Apr 12;52(4):1471-8. doi: 10.3233/JAD-160149.

PMID:
27079728
15.

Astrocyte Resilience to Oxidative Stress Induced by Insulin-like Growth Factor I (IGF-I) Involves Preserved AKT (Protein Kinase B) Activity.

Dávila D, Fernández S, Torres-Alemán I.

J Biol Chem. 2016 Jan 29;291(5):2510-23. doi: 10.1074/jbc.M115.695478. Epub 2015 Dec 2. Retraction in: J Biol Chem. 2016 Jun 3;291(23):12039.

16.

Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury.

Genis L, Dávila D, Fernandez S, Pozo-Rodrigálvarez A, Martínez-Murillo R, Torres-Aleman I.

Version 2. F1000Res. 2014 Jan 28 [revised 2014 Jan 1];3:28. doi: 10.12688/f1000research.3-28.v2. eCollection 2014.

17.

IGF-1 in autosomal dominant cerebellar ataxia - open-label trial.

Sanz-Gallego I, Rodriguez-de-Rivera FJ, Pulido I, Torres-Aleman I, Arpa J.

Cerebellum Ataxias. 2014 Oct 2;1:13. doi: 10.1186/s40673-014-0013-8. eCollection 2014.

18.

IGF-1 in Friedreich's Ataxia - proof-of-concept trial.

Sanz-Gallego I, Torres-Aleman I, Arpa J.

Cerebellum Ataxias. 2014 Jul 4;1:10. doi: 10.1186/2053-8871-1-10. eCollection 2014.

19.

Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice.

Trueba-Sáiz A, Cavada C, Fernandez AM, Leon T, González DA, Fortea Ormaechea J, Lleó A, Del Ser T, Nuñez A, Torres-Aleman I.

Transl Psychiatry. 2013 Dec 3;3:e330. doi: 10.1038/tp.2013.102.

20.

A phosphatase-independent gain-of-function mutation in PTEN triggers aberrant cell growth in astrocytes through an autocrine IGF-1 loop.

Fernández S, Genis L, Torres-Alemán I.

Oncogene. 2014 Aug 7;33(32):4114-22. doi: 10.1038/onc.2013.376. Epub 2013 Sep 23.

PMID:
24056966

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