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Items: 1 to 20 of 368

1.

Approaches to target tractability assessment - a practical perspective.

Brown KK, Hann MM, Lakdawala AS, Santos R, Thomas PJ, Todd K.

Medchemcomm. 2018 Feb 14;9(4):606-613. doi: 10.1039/c7md00633k. eCollection 2018 Apr 1. Review.

PMID:
30108951
2.

CFTR modulator theratyping: Current status, gaps and future directions.

Clancy JP, Cotton CU, Donaldson SH, Solomon GM, VanDevanter DR, Boyle MP, Gentzsch M, Nick JA, Illek B, Wallenburg JC, Sorscher EJ, Amaral MD, Beekman JM, Naren AP, Bridges RJ, Thomas PJ, Cutting G, Rowe S, Durmowicz AG, Mense M, Boeck KD, Skach W, Penland C, Joseloff E, Bihler H, Mahoney J, Borowitz D, Tuggle KL.

J Cyst Fibros. 2018 Jun 19. pii: S1569-1993(18)30585-X. doi: 10.1016/j.jcf.2018.05.004. [Epub ahead of print] Review.

3.

Stochastic shielding and edge importance for Markov chains with timescale separation.

Schmidt DR, Galán RF, Thomas PJ.

PLoS Comput Biol. 2018 Jun 18;14(6):e1006206. doi: 10.1371/journal.pcbi.1006206. eCollection 2018 Jun.

4.

Welcome from the new Editor(s)-in-Chief.

Lindner B, Thomas PJ, Fellous JM.

Biol Cybern. 2018 Jun 7. doi: 10.1007/s00422-018-0760-3. [Epub ahead of print] No abstract available.

PMID:
29882190
5.

Pathogenic Signal Sequence Mutations in Progranulin Disrupt SRP Interactions Required for mRNA Stability.

Pinarbasi ES, Karamyshev AL, Tikhonova EB, Wu IH, Hudson H, Thomas PJ.

Cell Rep. 2018 Jun 5;23(10):2844-2851. doi: 10.1016/j.celrep.2018.05.003.

6.

Matador injury case report: Spermatic cord fat pad (SCFP) interposition to support complex pelvic reconstruction-a novel technique.

Zachou A, Mteta KA, Thomas PJ.

Urol Case Rep. 2018 Mar 31;18:87-88. doi: 10.1016/j.eucr.2018.03.016. eCollection 2018 May. No abstract available.

7.

Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization.

Pinarbasi ES, Cağatay T, Fung HYJ, Li YC, Chook YM, Thomas PJ.

Sci Rep. 2018 May 4;8(1):7083. doi: 10.1038/s41598-018-25008-4.

8.

Long-term culture and cloning of primary human bronchial basal cells that maintain multipotent differentiation capacity and CFTR channel function.

Peters-Hall JR, Coquelin ML, Torres MJ, LaRanger R, Alabi BR, Sho S, Calva-Moreno JF, Thomas PJ, Shay JW.

Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L313-L327. doi: 10.1152/ajplung.00355.2017. Epub 2018 May 3.

PMID:
29722564
9.

Neonicotinoid detection in wild turkeys (Meleagris gallopavo silvestris) in Ontario, Canada.

MacDonald AM, Jardine CM, Thomas PJ, Nemeth NM.

Environ Sci Pollut Res Int. 2018 Jun;25(16):16254-16260. doi: 10.1007/s11356-018-2093-0. Epub 2018 Apr 27.

10.

Enumeration of the constitutional isomers of environmentally relevant substituted polycyclic aromatic compounds.

Johnson W, Idowu I, Francisco O, Marvin C, Thomas PJ, Stetefeld J, Tomy GT.

Chemosphere. 2018 Jul;202:9-16. doi: 10.1016/j.chemosphere.2018.03.035. Epub 2018 Mar 6.

PMID:
29567615
11.

Heavy Rare Earth Elements Affect Sphaerechinus granularis Sea Urchin Early Life Stages by Multiple Toxicity Endpoints.

Gravina M, Pagano G, Oral R, Guida M, Toscanesi M, Siciliano A, Di Nunzio A, Burić P, Lyons DM, Thomas PJ, Trifuoggi M.

Bull Environ Contam Toxicol. 2018 May;100(5):641-646. doi: 10.1007/s00128-018-2309-5. Epub 2018 Mar 2.

PMID:
29500496
12.

Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance.

Weingarten RA, Johnson RC, Conlan S, Ramsburg AM, Dekker JP, Lau AF, Khil P, Odom RT, Deming C, Park M, Thomas PJ; NISC Comparative Sequencing Program, Henderson DK, Palmore TN, Segre JA, Frank KM.

MBio. 2018 Feb 6;9(1). pii: e02011-17. doi: 10.1128/mBio.02011-17.

13.

Airborne polycyclic aromatic compounds contribute to the induction of the tumour-suppressing P53 pathway in wild double-crested cormorants.

Wallace SJ, de Solla SR, Thomas PJ, Harner T, Eng A, Langlois VS.

Ecotoxicol Environ Saf. 2018 Apr 15;150:176-189. doi: 10.1016/j.ecoenv.2017.12.028. Epub 2017 Dec 22.

14.

Validation of a simultaneous method for determining polycyclic aromatic compounds and alkylated isomers in biota.

Idowu I, Francisco O, Thomas PJ, Johnson W, Marvin C, Stetefeld J, Tomy GT.

Rapid Commun Mass Spectrom. 2018 Feb 15;32(3):277-287. doi: 10.1002/rcm.8035.

15.

17β-Estradiol Dysregulates Innate Immune Responses to Pseudomonas aeruginosa Respiratory Infection and Is Modulated by Estrogen Receptor Antagonism.

Abid S, Xie S, Bose M, Shaul PW, Terada LS, Brody SL, Thomas PJ, Katzenellenbogen JA, Kim SH, Greenberg DE, Jain R.

Infect Immun. 2017 Sep 20;85(10). pii: e00422-17. doi: 10.1128/IAI.00422-17. Print 2017 Oct.

16.

Eupnea, tachypnea, and autoresuscitation in a closed-loop respiratory control model.

Diekman CO, Thomas PJ, Wilson CG.

J Neurophysiol. 2017 Oct 1;118(4):2194-2215. doi: 10.1152/jn.00170.2017. Epub 2017 Jul 19.

PMID:
28724778
17.

Comparative toxicity of seven rare earth elements in sea urchin early life stages.

Trifuoggi M, Pagano G, Guida M, Palumbo A, Siciliano A, Gravina M, Lyons DM, Burić P, Levak M, Thomas PJ, Giarra A, Oral R.

Environ Sci Pollut Res Int. 2017 Sep;24(25):20803-20810. doi: 10.1007/s11356-017-9658-1. Epub 2017 Jul 18.

PMID:
28721613
18.

The dynamic excitation of a granular chain: Contact mechanics finite element analysis and experimental validation.

Gélat P, Yang J, Akanji O, Thomas PJ, Hutchins D, Harput S, Freear S, Saffari N.

J Acoust Soc Am. 2017 Jun;141(6):4240. doi: 10.1121/1.4983466.

19.

Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface.

Hudson RP, Dawson JE, Chong PA, Yang Z, Millen L, Thomas PJ, Brouillette CG, Forman-Kay JD.

Mol Pharmacol. 2017 Aug;92(2):124-135. doi: 10.1124/mol.117.108373. Epub 2017 May 25.

20.

Characteristics of nanocrystalline thin films of cadmium sulphide deposited at the water-oil interface.

Albrasi E, Kelly AJ, Johal S, O'Brien P, Baxter SN, Thomas PJ.

J Colloid Interface Sci. 2017 Jun 15;496:474-478. doi: 10.1016/j.jcis.2017.02.044. Epub 2017 Feb 22.

PMID:
28257966

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