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Items: 1 to 20 of 95


Fractional Flow Reserve and Instantaneous Wave-Free Ratio as Predictors of the Placebo-Controlled Response to Percutaneous Coronary Intervention in Stable Single-Vessel Coronary Artery Disease.

Al-Lamee R, Howard JP, Shun-Shin MJ, Thompson D, Dehbi HM, Sen S, Nijjer S, Petraco R, Davies J, Keeble T, Tang K, Malik IS, Cook C, Ahmad Y, Sharp ASP, Gerber R, Baker C, Kaprielian R, Talwar S, Assomull R, Cole G, Keenan NG, Kanaganayagam G, Sehmi J, Wensel R, Harrell FE, Mayet J, Thom SA, Davies JE, Francis DP.

Circulation. 2018 Oct 23;138(17):1780-1792. doi: 10.1161/CIRCULATIONAHA.118.033801.


Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial.

Al-Lamee R, Thompson D, Dehbi HM, Sen S, Tang K, Davies J, Keeble T, Mielewczik M, Kaprielian R, Malik IS, Nijjer SS, Petraco R, Cook C, Ahmad Y, Howard J, Baker C, Sharp A, Gerber R, Talwar S, Assomull R, Mayet J, Wensel R, Collier D, Shun-Shin M, Thom SA, Davies JE, Francis DP; ORBITA investigators.

Lancet. 2018 Jan 6;391(10115):31-40. doi: 10.1016/S0140-6736(17)32714-9. Epub 2017 Nov 2. Erratum in: Lancet. 2018 Jan 6;391(10115):30.


Effect of Monthly, High-Dose, Long-Term Vitamin D Supplementation on Central Blood Pressure Parameters: A Randomized Controlled Trial Substudy.

Sluyter JD, Camargo CA Jr, Stewart AW, Waayer D, Lawes CMM, Toop L, Khaw KT, Thom SAM, Hametner B, Wassertheurer S, Parker KH, Hughes AD, Scragg R.

J Am Heart Assoc. 2017 Oct 24;6(10). pii: e006802. doi: 10.1161/JAHA.117.006802.


Arterial waveform parameters in a large, population-based sample of adults: relationships with ethnicity and lifestyle factors.

Sluyter JD, Hughes AD, Thom SA, Lowe A, Camargo CA Jr, Hametner B, Wassertheurer S, Parker KH, Scragg RK.

J Hum Hypertens. 2017 May;31(5):305-312. doi: 10.1038/jhh.2016.78. Epub 2016 Dec 22. Erratum in: J Hum Hypertens. 2017 Nov;31(11):760.


Association of Retinopathy and Retinal Microvascular Abnormalities With Stroke and Cerebrovascular Disease.

Hughes AD, Falaschetti E, Witt N, Wijetunge S, Thom SA, Tillin T, Aldington SJ, Chaturvedi N.

Stroke. 2016 Nov;47(11):2862-2864. Epub 2016 Oct 11.


Impact of blood pressure on retinal microvasculature architecture across the lifespan: the Young Finns Study.

Tapp RJ, Hussain SM, Battista J, Hutri-Kähönen N, Lehtimäki T, Hughes AD, Thom SA, Metha A, Raitakari OT, Kähönen M.

Microcirculation. 2015 Feb;22(2):146-55. doi: 10.1111/micc.12187.


Evaluation of C-reactive protein before and on-treatment as a predictor of benefit of atorvastatin: a cohort analysis from the Anglo-Scandinavian Cardiac Outcomes Trial lipid-lowering arm.

Sever PS, Poulter NR, Chang CL, Thom SA, Hughes AD, Welsh P, Sattar N; ASCOT Investigators.

J Am Coll Cardiol. 2013 Aug 20;62(8):717-29. doi: 10.1016/j.jacc.2013.02.098.


A randomized placebo controlled double blind crossover study of pioglitazone on left ventricular diastolic function in type 2 diabetes.

Hughes AD, Park C, March K, Coady E, Khir A, Chaturvedi N, Thom SA.

Int J Cardiol. 2013 Aug 20;167(4):1329-32. doi: 10.1016/j.ijcard.2012.03.179. Epub 2012 Apr 21.


Assessment of energy requirement for the retinal arterial network in normal and hypertensive subjects.

Liu D, Wood NB, Witt N, Hughes AD, Thom SA, Xu XY.

J Biomech Eng. 2012 Jan;134(1):014501. doi: 10.1115/1.4005529.


Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial.

Sever PS, Poulter NR, Chang CL, Hingorani A, Thom SA, Hughes AD, Welsh P, Sattar N; ASCOT Investigators.

Eur Heart J. 2012 Feb;33(4):486-94. doi: 10.1093/eurheartj/ehr262. Epub 2011 Jul 28.


A novel measure to characterise optimality of diameter relationships at retinal vascular bifurcations.

Witt NW, Chapman N, Thom SA, Stanton AV, Parker KH, Hughes AD.

Artery Res. 2010 Sep;4(3):75-80.


Wave reflection predicts cardiovascular events in hypertensive individuals independent of blood pressure and other cardiovascular risk factors: an ASCOT (Anglo-Scandinavian Cardiac Outcome Trial) substudy.

Manisty C, Mayet J, Tapp RJ, Parker KH, Sever P, Poulter NR, Thom SA, Hughes AD; ASCOT Investigators.

J Am Coll Cardiol. 2010 Jun 29;56(1):24-30. doi: 10.1016/j.jacc.2010.03.030. Erratum in: J Am Coll Cardiol. 2011 Jan 4 ;57(1):117. Poulter, Neil H [corrected to Poulter, Neil R].


Indian Asians have poorer cardiovascular autonomic function than Europeans: this is due to greater hyperglycaemia and may contribute to their greater risk of heart disease.

Bathula R, Hughes AD, Panerai R, Potter J, Thom SA, Francis DP, Shore AC, Kooner J, Chaturvedi N.

Diabetologia. 2010 Oct;53(10):2120-8. doi: 10.1007/s00125-010-1818-5. Epub 2010 Jun 12.


Differential effects of antihypertensive treatment on left ventricular diastolic function: an ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) substudy.

Tapp RJ, Sharp A, Stanton AV, O'Brien E, Chaturvedi N, Poulter NR, Sever PS, Thom SA, Hughes AD, Mayet J; ASCOT Investigators.

J Am Coll Cardiol. 2010 Apr 27;55(17):1875-81. doi: 10.1016/j.jacc.2009.11.084.


MR image-based geometric and hemodynamic investigation of the right coronary artery with dynamic vessel motion.

Torii R, Keegan J, Wood NB, Dowsey AW, Hughes AD, Yang GZ, Firmin DN, Thom SA, Xu XY.

Ann Biomed Eng. 2010 Aug;38(8):2606-20. doi: 10.1007/s10439-010-0008-4. Epub 2010 Apr 3.


Computational analysis of oxygen transport in the retinal arterial network.

Liu D, Wood NB, Witt N, Hughes AD, Thom SA, Xu XY.

Curr Eye Res. 2009 Nov;34(11):945-56. doi: 10.3109/02713680903230079.


Tissue Doppler E/E' ratio is a powerful predictor of primary cardiac events in a hypertensive population: an ASCOT substudy.

Sharp AS, Tapp RJ, Thom SA, Francis DP, Hughes AD, Stanton AV, Zambanini A, O'Brien E, Chaturvedi N, Lyons S, Byrd S, Poulter NR, Sever PS, Mayet J; ASCOT Investigators.

Eur Heart J. 2010 Mar;31(6):747-52. doi: 10.1093/eurheartj/ehp498. Epub 2009 Nov 26.


Retinal arterioles have impaired reactivity to hyperoxia in type 1 diabetes.

Justesen BL, Mistry P, Chaturvedi N, Thom SA, Witt N, Köhler D, Hughes AD, Sjølie AK.

Acta Ophthalmol. 2010 Jun;88(4):453-7. doi: 10.1111/j.1755-3768.2009.01557.x. Epub 2009 Jul 21.


Determinants of retinal microvascular architecture in normal subjects.

Hughes AD, Wong TY, Witt N, Evans R, Thom SA, Klein BE, Chaturvedi N, Klein R.

Microcirculation. 2009 Feb;16(2):159-66. doi: 10.1080/10739680802353868.


Comparison of the retinal microvasculature in European and African-Caribbean people with diabetes.

Mahal S, Strain WD, Martinez-Perez ME, Thom SA, Chaturvedi N, Hughes AD.

Clin Sci (Lond). 2009 Aug 14;117(6):229-36. doi: 10.1042/CS20080538.


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