Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 51

1.

Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate.

Kaddurah-Daouk R, Hankemeier T, Scholl EH, Baillie R, Harms A, Stage C, Dalhoff KP, Jűrgens G, Taboureau O, Nzabonimpa GS, Motsinger-Reif AA, Thomsen R, Linnet K, Rasmussen HB; INDICES Consortium; Pharmacometabolomics Research Network.

CPT Pharmacometrics Syst Pharmacol. 2018 Aug;7(8):525-533. doi: 10.1002/psp4.12309.

2.

A systems biology approach to predictive developmental neurotoxicity of a larvicide used in the prevention of Zika virus transmission.

Audouze K, Taboureau O, Grandjean P.

Toxicol Appl Pharmacol. 2018 Sep 1;354:56-63. doi: 10.1016/j.taap.2018.02.014. Epub 2018 Feb 21.

PMID:
29476864
3.

Adverse outcome pathways: opportunities, limitations and open questions.

Leist M, Ghallab A, Graepel R, Marchan R, Hassan R, Bennekou SH, Limonciel A, Vinken M, Schildknecht S, Waldmann T, Danen E, van Ravenzwaay B, Kamp H, Gardner I, Godoy P, Bois FY, Braeuning A, Reif R, Oesch F, Drasdo D, Höhme S, Schwarz M, Hartung T, Braunbeck T, Beltman J, Vrieling H, Sanz F, Forsby A, Gadaleta D, Fisher C, Kelm J, Fluri D, Ecker G, Zdrazil B, Terron A, Jennings P, van der Burg B, Dooley S, Meijer AH, Willighagen E, Martens M, Evelo C, Mombelli E, Taboureau O, Mantovani A, Hardy B, Koch B, Escher S, van Thriel C, Cadenas C, Kroese D, van de Water B, Hengstler JG.

Arch Toxicol. 2017 Nov;91(11):3477-3505. doi: 10.1007/s00204-017-2045-3. Epub 2017 Oct 19. Review.

PMID:
29051992
4.

Network-based Approaches in Pharmacology.

Boezio B, Audouze K, Ducrot P, Taboureau O.

Mol Inform. 2017 Oct;36(10). doi: 10.1002/minf.201700048. Epub 2017 Jul 10. Review.

PMID:
28692140
5.

Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists.

Qvortrup K, Jensen JF, Sørensen MS, Kouskoumvekaki I, Petersen RK, Taboureau O, Kristiansen K, Nielsen TE.

PLoS One. 2017 Feb 28;12(2):e0162642. doi: 10.1371/journal.pone.0162642. eCollection 2017.

6.

Human Environmental Disease Network: A computational model to assess toxicology of contaminants.

Taboureau O, Audouze K.

ALTEX. 2017;34(2):289-300. doi: 10.14573/altex.1607201. Epub 2016 Oct 21.

7.

In Silico Systems Pharmacology to Assess Drug's Therapeutic and Toxic Effects.

Aguayo-Orozco A, Audouze K, Brunak S, Taboureau O.

Curr Pharm Des. 2016;22(46):6895-6902. doi: 10.2174/1381612822666160907093215. Review.

PMID:
27604605
8.

Synthesis and Biological Evaluations of Cytotoxic and Antiangiogenic Triterpenoids-Jacaranone Conjugates.

Sun H, Yue PY, Wang SR, Huo L, Zhao Y, Xie S, Kringelum JV, Lund O, Taboureau O, Zhou J, Wong RN, Fang WS.

Med Chem. 2016;12(8):775-785.

PMID:
27140183
9.

Investigating the impact of missense mutations in hCES1 by in silico structure-based approaches.

Nzabonimpa GS, Rasmussen HB, Brunak S, Taboureau O; INDICES Consortium.

Drug Metab Pers Ther. 2016 Feb 19. pii: /j/dmdi.ahead-of-print/dmpt-2015-0034/dmpt-2015-0034.xml. doi: 10.1515/dmpt-2015-0034. [Epub ahead of print]

PMID:
26900165
10.

ChemProt-3.0: a global chemical biology diseases mapping.

Kringelum J, Kjaerulff SK, Brunak S, Lund O, Oprea TI, Taboureau O.

Database (Oxford). 2016 Feb 13;2016. pii: bav123. doi: 10.1093/database/bav123. Print 2016.

11.

Chemical biology databases: from aggregation, curation to representation.

Audouze K, Taboureau O.

Drug Discov Today Technol. 2015 Jul;14:25-9. doi: 10.1016/j.ddtec.2015.03.003. Epub 2015 May 7. Review.

PMID:
26194584
12.

Evolution of substrate recognition sites (SRSs) in cytochromes P450 from Apiaceae exemplified by the CYP71AJ subfamily.

Dueholm B, Krieger C, Drew D, Olry A, Kamo T, Taboureau O, Weitzel C, Bourgaud F, Hehn A, Simonsen HT.

BMC Evol Biol. 2015 Jun 26;15:122. doi: 10.1186/s12862-015-0396-z.

13.

Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics.

Rasmussen HB, Bjerre D, Linnet K, Jürgens G, Dalhoff K, Stefansson H, Hankemeier T, Kaddurah-Daouk R, Taboureau O, Brunak S, Houmann T, Jeppesen P, Pagsberg AK, Plessen K, Dyrborg J, Hansen PR, Hansen PE, Hughes T, Werge T; INDICES Consortium.

Pharmacogenomics. 2015;16(6):649-65. doi: 10.2217/pgs.15.7. Epub 2015 Apr 21. Review.

PMID:
25896426
14.

Computational investigations of hERG channel blockers: New insights and current predictive models.

Villoutreix BO, Taboureau O.

Adv Drug Deliv Rev. 2015 Jun 23;86:72-82. doi: 10.1016/j.addr.2015.03.003. Epub 2015 Mar 12. Review.

PMID:
25770776
15.

Identification of odorant-receptor interactions by global mapping of the human odorome.

Audouze K, Tromelin A, Le Bon AM, Belloir C, Petersen RK, Kristiansen K, Brunak S, Taboureau O.

PLoS One. 2014 Apr 2;9(4):e93037. doi: 10.1371/journal.pone.0093037. eCollection 2014.

16.

Solid-phase synthesis and biological evaluation of N-dipeptido L-homoserine lactones as quorum sensing activators.

Hansen MR, Le Quement ST, Jakobsen TH, Skovstrup S, Taboureau O, Tolker-Nielsen T, Givskov M, Nielsen TE.

Chembiochem. 2014 Feb 10;15(3):460-5. doi: 10.1002/cbic.201300533. Epub 2014 Jan 16.

PMID:
24436223
17.

The effect of network biology on drug toxicology.

Gautier L, Taboureau O, Audouze K.

Expert Opin Drug Metab Toxicol. 2013 Nov;9(11):1409-18. doi: 10.1517/17425255.2013.820704. Epub 2013 Aug 12. Review.

PMID:
23937336
18.

Scientific competency questions as the basis for semantically enriched open pharmacological space development.

Azzaoui K, Jacoby E, Senger S, Rodríguez EC, Loza M, Zdrazil B, Pinto M, Williams AJ, de la Torre V, Mestres J, Pastor M, Taboureau O, Rarey M, Chichester C, Pettifer S, Blomberg N, Harland L, Williams-Jones B, Ecker GF.

Drug Discov Today. 2013 Sep;18(17-18):843-52. doi: 10.1016/j.drudis.2013.05.008. Epub 2013 May 20. Review.

19.

HExpoChem: a systems biology resource to explore human exposure to chemicals.

Taboureau O, Jacobsen UP, Kalhauge C, Edsgärd D, Rigina O, Gupta R, Audouze K.

Bioinformatics. 2013 May 1;29(9):1231-2. doi: 10.1093/bioinformatics/btt112. Epub 2013 Mar 11.

PMID:
23479352
20.

Discovery of a novel selective PPARγ ligand with partial agonist binding properties by integrated in silico/in vitro work flow.

Kouskoumvekaki I, Petersen RK, Fratev F, Taboureau O, Nielsen TE, Oprea TI, Sonne SB, Flindt EN, Jónsdóttir SÓ, Kristiansen K.

J Chem Inf Model. 2013 Apr 22;53(4):923-37. doi: 10.1021/ci3006148. Epub 2013 Mar 19.

PMID:
23432662

Supplemental Content

Loading ...
Support Center