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The short synacthen test and its utility in assessing recovery of adrenal function in patients with central adrenal insufficiency.

Sherlock M, Stewart PM.

J Clin Endocrinol Metab. 2018 Aug 3. doi: 10.1210/jc.2018-01317. [Epub ahead of print] No abstract available.


Health Care Burden in Patients With Adrenal Insufficiency.

Gunnarsson C, Ryan MP, Marelli C, Baker ER, Stewart PM, Johannsson G, Biller BMK.

J Endocr Soc. 2017 Apr 12;1(5):512-523. doi: 10.1210/js.2016-1064. eCollection 2017 May 1.


11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice.

Doig CL, Fletcher RS, Morgan SA, McCabe EL, Larner DP, Tomlinson JW, Stewart PM, Philp A, Lavery GG.

Endocrinology. 2017 Jun 1;158(6):1964-1976. doi: 10.1210/en.2016-1722.


25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression.

Hassan-Smith ZK, Jenkinson C, Smith DJ, Hernandez I, Morgan SA, Crabtree NJ, Gittoes NJ, Keevil BG, Stewart PM, Hewison M.

PLoS One. 2017 Feb 15;12(2):e0170665. doi: 10.1371/journal.pone.0170665. eCollection 2017.


Laparoscopic peritoneal lavage or surgical resection for acute perforated sigmoid diverticulitis: A systematic review and meta-analysis.

Shaikh FM, Stewart PM, Walsh SR, Davies RJ.

Int J Surg. 2017 Feb;38:130-137. doi: 10.1016/j.ijsu.2017.01.020. Epub 2017 Jan 9. Review.


Immediate versus modified release hydrocortisone in mitotane-treated patients with adrenocortical cancer.

Weigel M, Hahner S, Sherlock M, Agha A, Behan LA, Stewart PM, Arlt W, Beier D, Frey K, Zopf K, Quinkler M.

Clin Endocrinol (Oxf). 2017 Apr;86(4):499-505. doi: 10.1111/cen.13302. Epub 2017 Feb 3.


11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.

Hardy RS, Doig CL, Hussain Z, O'Leary M, Morgan SA, Pearson MJ, Naylor A, Jones SW, Filer A, Stewart PM, Buckley CD, Lavery GG, Cooper MS, Raza K.

J Pathol. 2016 Dec;240(4):472-483. doi: 10.1002/path.4806. Epub 2016 Oct 18.


SFRP2 Is Associated with Increased Adiposity and VEGF Expression.

Crowley RK, O'Reilly MW, Bujalska IJ, Hassan-Smith ZK, Hazlehurst JM, Foucault DR, Stewart PM, Tomlinson JW.

PLoS One. 2016 Sep 29;11(9):e0163777. doi: 10.1371/journal.pone.0163777. eCollection 2016.


Exploring Inpatient Hospitalizations and Morbidity in Patients With Adrenal Insufficiency.

Stewart PM, Biller BM, Marelli C, Gunnarsson C, Ryan MP, Johannsson G.

J Clin Endocrinol Metab. 2016 Dec;101(12):4843-4850. Epub 2016 Sep 13.


Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease.

Larner DP, Morgan SA, Gathercole LL, Doig CL, Guest P, Weston C, Hazeldine J, Tomlinson JW, Stewart PM, Lavery GG.

Endocrinology. 2016 Sep;157(9):3493-504. doi: 10.1210/en.2016-1357. Epub 2016 Jul 6.


Mortality in patients with Cushing's disease more than 10 years after remission: a multicentre, multinational, retrospective cohort study.

Clayton RN, Jones PW, Reulen RC, Stewart PM, Hassan-Smith ZK, Ntali G, Karavitaki N, Dekkers OM, Pereira AM, Bolland M, Holdaway I, Lindholm J.

Lancet Diabetes Endocrinol. 2016 Jul;4(7):569-76. doi: 10.1016/S2213-8587(16)30005-5. Epub 2016 Jun 2.


Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism.

Morgan SA, Hassan-Smith ZK, Doig CL, Sherlock M, Stewart PM, Lavery GG.

J Endocrinol. 2016 Jun;229(3):277-86. doi: 10.1530/JOE-16-0011. Epub 2016 Apr 5.


High throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum.

Jenkinson C, Taylor AE, Hassan-Smith ZK, Adams JS, Stewart PM, Hewison M, Keevil BG.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 1;1014:56-63. doi: 10.1016/j.jchromb.2016.01.049. Epub 2016 Feb 2.



Dineen R, Stewart PM, Sherlock M.

QJM. 2017 Jul 1;110(7):411-420. doi: 10.1093/qjmed/hcw004. Review.


Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol.

Woods CP, Argese N, Chapman M, Boot C, Webster R, Dabhi V, Grossman AB, Toogood AA, Arlt W, Stewart PM, Crowley RK, Tomlinson JW.

Eur J Endocrinol. 2015 Nov;173(5):633-42. doi: 10.1530/EJE-15-0608. Epub 2015 Aug 20.


The modulation of corticosteroid metabolism by hydrocortisone therapy in patients with hypopituitarism increases tissue glucocorticoid exposure.

Sherlock M, Behan LA, Hannon MJ, Alonso AA, Thompson CJ, Murray RD, Crabtree N, Hughes BA, Arlt W, Agha A, Toogood AA, Stewart PM.

Eur J Endocrinol. 2015 Nov;173(5):583-93. doi: 10.1530/EJE-15-0490. Epub 2015 Aug 11.


Gender-Specific Differences in Skeletal Muscle 11β-HSD1 Expression Across Healthy Aging.

Hassan-Smith ZK, Morgan SA, Sherlock M, Hughes B, Taylor AE, Lavery GG, Tomlinson JW, Stewart PM.

J Clin Endocrinol Metab. 2015 Jul;100(7):2673-81. doi: 10.1210/jc.2015-1516. Epub 2015 May 19.


Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis.

Nanus DE, Filer AD, Yeo L, Scheel-Toellner D, Hardy R, Lavery GG, Stewart PM, Buckley CD, Tomlinson JW, Cooper MS, Raza K.

Arthritis Res Ther. 2015 May 14;17:121. doi: 10.1186/s13075-015-0633-2.


Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS).

Dancer RC, Parekh D, Lax S, D'Souza V, Zheng S, Bassford CR, Park D, Bartis DG, Mahida R, Turner AM, Sapey E, Wei W, Naidu B, Stewart PM, Fraser WD, Christopher KB, Cooper MS, Gao F, Sansom DM, Martineau AR, Perkins GD, Thickett DR.

Thorax. 2015 Jul;70(7):617-24. doi: 10.1136/thoraxjnl-2014-206680. Epub 2015 Apr 22.


Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT).

Woods CP, Corrigan M, Gathercole L, Taylor A, Hughes B, Gaoatswe G, Manolopoulos K, Hogan AE, O'Connell J, Stewart PM, Tomlinson JW, O'Shea D, Sherlock M.

J Clin Endocrinol Metab. 2015 Apr;100(4):1434-44. doi: 10.1210/jc.2014-4120. Epub 2015 Jan 20.


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