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Items: 1 to 20 of 21

1.

GZ-793A inhibits the neurochemical effects of methamphetamine via a selective interaction with the vesicular monoamine transporter-2.

Nickell JR, Siripurapu KB, Horton DB, Zheng G, Crooks PA, Dwoskin LP.

Eur J Pharmacol. 2017 Jan 15;795:143-149. doi: 10.1016/j.ejphar.2016.12.016. Epub 2016 Dec 13.

PMID:
27986625
2.

Novel multifunctional pharmacology of lobinaline, the major alkaloid from Lobelia cardinalis.

Brown DP, Rogers DT, Pomerleau F, Siripurapu KB, Kulshrestha M, Gerhardt GA, Littleton JM.

Fitoterapia. 2016 Jun;111:109-23. doi: 10.1016/j.fitote.2016.04.013. Epub 2016 Apr 20.

3.

The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse.

Nickell JR, Siripurapu KB, Vartak A, Crooks PA, Dwoskin LP.

Adv Pharmacol. 2014;69:71-106. doi: 10.1016/B978-0-12-420118-7.00002-0. Review.

4.

Potential therapeutic uses of mecamylamine and its stereoisomers.

Nickell JR, Grinevich VP, Siripurapu KB, Smith AM, Dwoskin LP.

Pharmacol Biochem Behav. 2013 Jul;108:28-43. doi: 10.1016/j.pbb.2013.04.005. Epub 2013 Apr 18. Review.

5.

Corrigendum to "Evolvosides C-E, flavonol-4'-O-triglycosides from Evolvulus alsinoides and their anti-stress activity" [Bioorg. Med. Chem. 21 (2013) 1116-1122].

Gupta P, Sharma U, Gupta P, Siripurapu KB, Maurya R.

Bioorg Med Chem. 2013 Apr 15;21(8):2426. doi: 10.1016/j.bmc.2013.02.031. Epub 2013 Mar 6. No abstract available.

PMID:
28689777
6.

Structural modifications to tetrahydropyridine-3-carboxylate esters en route to the discovery of M5-preferring muscarinic receptor orthosteric antagonists.

Zheng G, Smith AM, Huang X, Subramanian KL, Siripurapu KB, Deaciuc A, Zhan CG, Dwoskin LP.

J Med Chem. 2013 Feb 28;56(4):1693-703. doi: 10.1021/jm301774u. Epub 2013 Feb 18.

7.

Evolvosides C–E, flavonol-4'-O-triglycosides from evolvulus alsinoides and their anti-stress activity [corrected].

Gupta P, Sharma U, Gupta P, Siripurapu KB, Maurya R.

Bioorg Med Chem. 2013 Mar 1;21(5):1116-22. doi: 10.1016/j.bmc.2012.12.040. Epub 2013 Jan 10. Erratum in: Bioorg Med Chem. 2013 Apr 15;21(8):2426.

PMID:
23357036
8.

Novel Ocimumoside A and B as anti-stress agents: modulation of brain monoamines and antioxidant systems in chronic unpredictable stress model in rats.

Ahmad A, Rasheed N, Gupta P, Singh S, Siripurapu KB, Ashraf GM, Kumar R, Chand K, Maurya R, Banu N, Al-Sheeha M, Palit G.

Phytomedicine. 2012 May 15;19(7):639-47. doi: 10.1016/j.phymed.2012.02.012. Epub 2012 Mar 26.

PMID:
22455995
9.

Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release.

Horton DB, Siripurapu KB, Zheng G, Crooks PA, Dwoskin LP.

J Pharmacol Exp Ther. 2011 Oct;339(1):286-97. doi: 10.1124/jpet.111.184770. Epub 2011 Jul 21.

10.

bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse.

Wooters TE, Smith AM, Pivavarchyk M, Siripurapu KB, McIntosh JM, Zhang Z, Crooks PA, Bardo MT, Dwoskin LP.

Br J Pharmacol. 2011 May;163(2):346-57. doi: 10.1111/j.1476-5381.2011.01220.x.

11.

meso-Transdiene analogs inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release.

Horton DB, Siripurapu KB, Norrholm SD, Culver JP, Hojahmat M, Beckmann JS, Harrod SB, Deaciuc AG, Bardo MT, Crooks PA, Dwoskin LP.

J Pharmacol Exp Ther. 2011 Mar;336(3):940-51. doi: 10.1124/jpet.110.175117. Epub 2010 Dec 21.

12.

The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats.

Beckmann JS, Siripurapu KB, Nickell JR, Horton DB, Denehy ED, Vartak A, Crooks PA, Dwoskin LP, Bardo MT.

J Pharmacol Exp Ther. 2010 Dec;335(3):841-51. doi: 10.1124/jpet.110.172742. Epub 2010 Aug 30.

13.

Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2.

Nickell JR, Krishnamurthy S, Norrholm S, Deaciuc G, Siripurapu KB, Zheng G, Crooks PA, Dwoskin LP.

J Pharmacol Exp Ther. 2010 Feb;332(2):612-21. doi: 10.1124/jpet.109.160275. Epub 2009 Oct 23.

14.

The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices.

Smith AM, Dhawan GK, Zhang Z, Siripurapu KB, Crooks PA, Dwoskin LP.

Biochem Pharmacol. 2009 Oct 1;78(7):889-97. doi: 10.1016/j.bcp.2009.07.010. Epub 2009 Jul 23.

15.

N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity.

Dwoskin LP, Wooters TE, Sumithran SP, Siripurapu KB, Joyce BM, Lockman PR, Manda VK, Ayers JT, Zhang Z, Deaciuc AG, McIntosh JM, Crooks PA, Bardo MT.

J Pharmacol Exp Ther. 2008 Aug;326(2):563-76. doi: 10.1124/jpet.108.136630. Epub 2008 May 6.

16.

Involvement of monoamines and proinflammatory cytokines in mediating the anti-stress effects of Panax quinquefolium.

Rasheed N, Tyagi E, Ahmad A, Siripurapu KB, Lahiri S, Shukla R, Palit G.

J Ethnopharmacol. 2008 May 8;117(2):257-62. doi: 10.1016/j.jep.2008.01.035. Epub 2008 Feb 8.

PMID:
18339495
17.

Constituents of Ocimum sanctum with antistress activity.

Gupta P, Yadav DK, Siripurapu KB, Palit G, Maurya R.

J Nat Prod. 2007 Sep;70(9):1410-6. Epub 2007 Sep 13.

PMID:
17850106
18.

Anti-stress constituents of Evolvulus alsinoides: an ayurvedic crude drug.

Gupta P, Akanksha, Siripurapu KB, Ahmad A, Palit G, Arora A, Maurya R.

Chem Pharm Bull (Tokyo). 2007 May;55(5):771-5.

19.

Effect of Bacopa monniera on stress induced changes in plasma corticosterone and brain monoamines in rats.

Sheikh N, Ahmad A, Siripurapu KB, Kuchibhotla VK, Singh S, Palit G.

J Ethnopharmacol. 2007 May 22;111(3):671-6. Epub 2007 Jan 30.

PMID:
17321089
20.

Adaptogenic and anti-amnesic properties of Evolvulus alsinoides in rodents.

Siripurapu KB, Gupta P, Bhatia G, Maurya R, Nath C, Palit G.

Pharmacol Biochem Behav. 2005 Jul;81(3):424-32.

PMID:
15899513

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