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Items: 12

1.

PX-18 Protects Human Saphenous Vein Endothelial Cells under Arterial Blood Pressure.

Kupreishvili K, Stooker W, Emmens RW, Vonk ABA, Sipkens JA, van Dijk A, Eijsman L, Quax PH, van Hinsbergh VWM, Krijnen PAJ, Niessen HWM.

Ann Vasc Surg. 2017 Jul;42:293-298. doi: 10.1016/j.avsg.2016.10.063. Epub 2017 Mar 11.

PMID:
28300679
2.

A sensitive, reproducible and objective immunofluorescence analysis method of dystrophin in individual fibers in samples from patients with duchenne muscular dystrophy.

Beekman C, Sipkens JA, Testerink J, Giannakopoulos S, Kreuger D, van Deutekom JC, Campion GV, de Kimpe SJ, Lourbakos A.

PLoS One. 2014 Sep 22;9(9):e107494. doi: 10.1371/journal.pone.0107494. eCollection 2014.

3.

The Dynamics of Compound, Transcript, and Protein Effects After Treatment With 2OMePS Antisense Oligonucleotides in mdx Mice.

Verhaart IE, van Vliet-van den Dool L, Sipkens JA, de Kimpe SJ, Kolfschoten IG, van Deutekom JC, Liefaard L, Ridings JE, Hood SR, Aartsma-Rus A.

Mol Ther Nucleic Acids. 2014 Feb 18;3:e148. doi: 10.1038/mtna.2014.1.

4.

S-Adenosylhomocysteine induces apoptosis and phosphatidylserine exposure in endothelial cells independent of homocysteine.

Sipkens JA, Hahn NE, Blom HJ, Lougheed SM, Stehouwer CD, Rauwerda JA, Krijnen PA, van Hinsbergh VW, Niessen HW.

Atherosclerosis. 2012 Mar;221(1):48-54. doi: 10.1016/j.atherosclerosis.2011.11.032. Epub 2011 Nov 28.

PMID:
22204864
5.

Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients.

Krijnen PA, Hahn NE, Kholová I, Baylan U, Sipkens JA, van Alphen FP, Vonk AB, Simsek S, Meischl C, Schalkwijk CG, van Buul JD, van Hinsbergh VW, Niessen HW.

Basic Res Cardiol. 2012 Jan;107(1):233. doi: 10.1007/s00395-011-0233-5. Epub 2011 Dec 14.

6.

Homocysteine-induced apoptosis in endothelial cells coincides with nuclear NOX2 and peri-nuclear NOX4 activity.

Sipkens JA, Hahn N, van den Brand CS, Meischl C, Cillessen SA, Smith DE, Juffermans LJ, Musters RJ, Roos D, Jakobs C, Blom HJ, Smulders YM, Krijnen PA, Stehouwer CD, Rauwerda JA, van Hinsbergh VW, Niessen HW.

Cell Biochem Biophys. 2013 Nov;67(2):341-52. doi: 10.1007/s12013-011-9297-y.

7.

Homocysteine induces phosphatidylserine exposure in cardiomyocytes through inhibition of Rho kinase and flippase activity.

Sipkens JA, Hahn NE, van Nieuw-Amerongen GP, Stehouwer CD, Rauwerda JA, van Hinsbergh VW, Niessen HW, Krijnen PA.

Cell Physiol Biochem. 2011;28(1):53-62. doi: 10.1159/000331713. Epub 2011 Aug 16.

8.

Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox).

Sipkens JA, Krijnen PA, Hahn NE, Wassink M, Meischl C, Smith DE, Musters RJ, Stehouwer CD, Rauwerda JA, van Hinsbergh VW, Niessen HW.

Mol Cell Biochem. 2011 Dec;358(1-2):229-39. doi: 10.1007/s11010-011-0973-4. Epub 2011 Jul 8.

PMID:
21739151
9.

Systemic administration of PRO051 in Duchenne's muscular dystrophy.

Goemans NM, Tulinius M, van den Akker JT, Burm BE, Ekhart PF, Heuvelmans N, Holling T, Janson AA, Platenburg GJ, Sipkens JA, Sitsen JM, Aartsma-Rus A, van Ommen GJ, Buyse G, Darin N, Verschuuren JJ, Campion GV, de Kimpe SJ, van Deutekom JC.

N Engl J Med. 2011 Apr 21;364(16):1513-22. doi: 10.1056/NEJMoa1011367. Epub 2011 Mar 23. Erratum in: N Engl J Med. 2011 Oct 6;365(14):1361.

10.

Inhibition of Rho-ROCK signaling induces apoptotic and non-apoptotic PS exposure in cardiomyocytes via inhibition of flippase.

Krijnen PA, Sipkens JA, Molling JW, Rauwerda JA, Stehouwer CD, Muller A, Paulus WJ, van Nieuw Amerongen GP, Hack CE, Verhoeven AJ, van Hinsbergh VW, Niessen HW.

J Mol Cell Cardiol. 2010 Nov;49(5):781-90. doi: 10.1016/j.yjmcc.2010.07.017. Epub 2010 Aug 5.

PMID:
20691698
11.

Homocysteine affects cardiomyocyte viability: concentration-dependent effects on reversible flip-flop, apoptosis and necrosis.

Sipkens JA, Krijnen PA, Meischl C, Cillessen SA, Smulders YM, Smith DE, Giroth CP, Spreeuwenberg MD, Musters RJ, Muller A, Jakobs C, Roos D, Stehouwer CD, Rauwerda JA, van Hinsbergh VW, Niessen HW.

Apoptosis. 2007 Aug;12(8):1407-18.

12.

Ischemia induces nuclear NOX2 expression in cardiomyocytes and subsequently activates apoptosis.

Meischl C, Krijnen PA, Sipkens JA, Cillessen SA, Muñoz IG, Okroj M, Ramska M, Muller A, Visser CA, Musters RJ, Simonides WS, Hack CE, Roos D, Niessen HW.

Apoptosis. 2006 Jun;11(6):913-21.

PMID:
16544099

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