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Items: 1 to 20 of 226

1.

The Role of E3, E4 Ubiquitin Ligase (UBE4B) in Human Pathologies.

Antoniou N, Lagopati N, Balourdas DI, Nikolaou M, Papalampros A, Vasileiou PVS, Myrianthopoulos V, Kotsinas A, Shiloh Y, Liontos M, Gorgoulis VG.

Cancers (Basel). 2019 Dec 24;12(1). pii: E62. doi: 10.3390/cancers12010062. Review.

2.

The EXPANDER Integrated Platform for Transcriptome Analysis.

Hait TA, Maron-Katz A, Sagir D, Amar D, Ulitsky I, Linhart C, Tanay A, Sharan R, Shiloh Y, Elkon R, Shamir R.

J Mol Biol. 2019 Jun 14;431(13):2398-2406. doi: 10.1016/j.jmb.2019.05.013. Epub 2019 May 14.

3.

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors.

Jachimowicz RD, Beleggia F, Isensee J, Velpula BB, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y.

Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3.

4.

Inactive Atm abrogates DSB repair in mouse cerebellum more than does Atm loss, without causing a neurological phenotype.

Tal E, Alfo M, Zha S, Barzilai A, De Zeeuw CI, Ziv Y, Shiloh Y.

DNA Repair (Amst). 2018 Dec;72:10-17. doi: 10.1016/j.dnarep.2018.10.001. Epub 2018 Oct 11.

5.

The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.

Baranes-Bachar K, Levy-Barda A, Oehler J, Reid DA, Soria-Bretones I, Voss TC, Chung D, Park Y, Liu C, Yoon JB, Li W, Dellaire G, Misteli T, Huertas P, Rothenberg E, Ramadan K, Ziv Y, Shiloh Y.

Mol Cell. 2018 Mar 1;69(5):866-878.e7. doi: 10.1016/j.molcel.2018.02.002.

6.

Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.

Gavish-Izakson M, Velpula BB, Elkon R, Prados-Carvajal R, Barnabas GD, Ugalde AP, Agami R, Geiger T, Huertas P, Ziv Y, Shiloh Y.

Nucleic Acids Res. 2018 Jan 25;46(2):730-747. doi: 10.1093/nar/gkx1240.

7.

Corrigendum: The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.

Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, Johnsen SA, Vojtesek B, Berger SL, Oren M.

Genes Dev. 2017 Sep 15;31(18):1926. doi: 10.1101/gad.307207.117. No abstract available.

8.

Monitoring the ATM-Mediated DNA Damage Response in the Cerebellum Using Organotypic Cultures.

Tal E, Shiloh Y.

Methods Mol Biol. 2017;1599:419-430. doi: 10.1007/978-1-4939-6955-5_30.

PMID:
28477136
9.

Ataxia-telangiectasia (A-T): An emerging dimension of premature ageing.

Shiloh Y, Lederman HM.

Ageing Res Rev. 2017 Jan;33:76-88. doi: 10.1016/j.arr.2016.05.002. Epub 2016 May 12. Review.

PMID:
27181190
10.

Genome instability: Linking ageing and brain degeneration.

Barzilai A, Schumacher B, Shiloh Y.

Mech Ageing Dev. 2017 Jan;161(Pt A):4-18. doi: 10.1016/j.mad.2016.03.011. Epub 2016 Mar 31. Review.

PMID:
27041231
11.

Systemic DNA damage responses in aging and diseases.

Ribezzo F, Shiloh Y, Schumacher B.

Semin Cancer Biol. 2016 Jun;37-38:26-35. doi: 10.1016/j.semcancer.2015.12.005. Epub 2016 Jan 7. Review.

12.

The COP9 signalosome is vital for timely repair of DNA double-strand breaks.

Meir M, Galanty Y, Kashani L, Blank M, Khosravi R, Fernández-Ávila MJ, Cruz-García A, Star A, Shochot L, Thomas Y, Garrett LJ, Chamovitz DA, Bodine DM, Kurz T, Huertas P, Ziv Y, Shiloh Y.

Nucleic Acids Res. 2015 May 19;43(9):4517-30. doi: 10.1093/nar/gkv270. Epub 2015 Apr 8.

13.

ATM: expanding roles as a chief guardian of genome stability.

Shiloh Y.

Exp Cell Res. 2014 Nov 15;329(1):154-61. doi: 10.1016/j.yexcr.2014.09.002. Epub 2014 Sep 8. Review. No abstract available.

PMID:
25218947
14.

Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation.

Rashi-Elkeles S, Warnatz HJ, Elkon R, Kupershtein A, Chobod Y, Paz A, Amstislavskiy V, Sultan M, Safer H, Nietfeld W, Lehrach H, Shamir R, Yaspo ML, Shiloh Y.

Sci Signal. 2014 May 13;7(325):rs3. doi: 10.1126/scisignal.2005032.

PMID:
24825921
15.

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.

Shiloh Y, Ziv Y.

Nat Rev Mol Cell Biol. 2013 Apr;14(4):197-210. Review.

PMID:
23847781
16.

DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population.

Rasmussen LJ, Shiloh Y, Bergersen LH, Sander M, Bohr VA, Tønjum T.

Mech Ageing Dev. 2013 Oct;134(10):427-33. doi: 10.1016/j.mad.2013.05.001. Epub 2013 May 10. Review. No abstract available.

17.

Studying the cerebellar DNA damage response in the tissue culture dish.

Tzur-Gilat A, Ziv Y, Mittelman L, Barzilai A, Shiloh Y.

Mech Ageing Dev. 2013 Oct;134(10):496-505. doi: 10.1016/j.mad.2013.04.001. Epub 2013 Apr 9.

PMID:
23583690
18.

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.

Shiloh Y, Ziv Y.

Nat Rev Mol Cell Biol. 2013 Apr;14(4):197-210. doi: 10.1038/nrm3546. Epub 2013 Mar 13. Review.

PMID:
23486281
19.

The ATM protein: the importance of being active.

Shiloh Y, Ziv Y.

J Cell Biol. 2012 Aug 6;198(3):273-5. doi: 10.1083/jcb.201207063.

20.

Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks.

Levy-Barda A, Lerenthal Y, Davis AJ, Chung YM, Essers J, Shao Z, van Vliet N, Chen DJ, Hu MC, Kanaar R, Ziv Y, Shiloh Y.

Cell Cycle. 2011 Dec 15;10(24):4300-10. doi: 10.4161/cc.10.24.18642. Epub 2011 Dec 15.

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