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Items: 1 to 20 of 104


Loss of p300 accelerates MDS-associated leukemogenesis.

Cheng G, Liu F, Asai T, Lai F, Man N, Xu H, Chen S, Greenblatt S, Hamard PJ, Ando K, Martinez C, Tadi M, Wang L, Xu M, Yang FC, Shiekhattar R, Nimer SD.

Leukemia. 2016 Nov 24. doi: 10.1038/leu.2016.347. [Epub ahead of print]


Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer.

Witt AE, Lee CW, Lee TI, Azzam DJ, Wang B, Caslini C, Petrocca F, Grosso J, Jones M, Cohick EB, Gropper AB, Wahlestedt C, Richardson AL, Shiekhattar R, Young RA, Ince TA.

Oncogene. 2016 Oct 3. doi: 10.1038/onc.2016.337. [Epub ahead of print]


A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy.

Yang M, Liang C, Swaminathan K, Herrlinger S, Lai F, Shiekhattar R, Chen JF.

Sci Adv. 2016 Sep 2;2(9):e1601167. doi: 10.1126/sciadv.1601167.


ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes.

Li N, Li Y, Lv J, Zheng X, Wen H, Shen H, Zhu G, Chen TY, Dhar SS, Kan PY, Wang Z, Shiekhattar R, Shi X, Lan F, Chen K, Li W, Li H, Lee MG.

Mol Cell. 2016 Aug 4;63(3):470-84. doi: 10.1016/j.molcel.2016.06.035.


Detection and Analysis of Long Noncoding RNAs.

Lai F, Blumenthal E, Shiekhattar R.

Methods Enzymol. 2016;573:421-44. doi: 10.1016/bs.mie.2016.03.010.


Diverse regulatory interactions of long noncoding RNAs.

Kim TK, Shiekhattar R.

Curr Opin Genet Dev. 2016 Feb;36:73-82. doi: 10.1016/j.gde.2016.03.014. Review.


Architectural and Functional Commonalities between Enhancers and Promoters.

Kim TK, Shiekhattar R.

Cell. 2015 Aug 27;162(5):948-59. doi: 10.1016/j.cell.2015.08.008. Review.


Integrator mediates the biogenesis of enhancer RNAs.

Lai F, Gardini A, Zhang A, Shiekhattar R.

Nature. 2015 Sep 17;525(7569):399-403. doi: 10.1038/nature14906.


PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II.

Chen FX, Woodfin AR, Gardini A, Rickels RA, Marshall SA, Smith ER, Shiekhattar R, Shilatifard A.

Cell. 2015 Aug 27;162(5):1003-15. doi: 10.1016/j.cell.2015.07.042.


The many faces of long noncoding RNAs.

Gardini A, Shiekhattar R.

FEBS J. 2015 May;282(9):1647-57. doi: 10.1111/febs.13101. Review.


Regulation of transcription by long noncoding RNAs.

Bonasio R, Shiekhattar R.

Annu Rev Genet. 2014;48:433-55. doi: 10.1146/annurev-genet-120213-092323. Review.


Integrator regulates transcriptional initiation and pause release following activation.

Gardini A, Baillat D, Cesaroni M, Hu D, Marinis JM, Wagner EJ, Lazar MA, Shilatifard A, Shiekhattar R.

Mol Cell. 2014 Oct 2;56(1):128-39. doi: 10.1016/j.molcel.2014.08.004.


Role of UTX in retinoic acid receptor-mediated gene regulation in leukemia.

Rocha-Viegas L, Villa R, Gutierrez A, Iriondo O, Shiekhattar R, Di Croce L.

Mol Cell Biol. 2014 Oct 1;34(19):3765-75. doi: 10.1128/MCB.00839-14.


Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response.

Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, Kennedy BK, Kaeberlein M, Berger SL.

Cell Metab. 2014 Jun 3;19(6):952-66. doi: 10.1016/j.cmet.2014.04.004.


Genome-wide analysis reveals a role for BRCA1 and PALB2 in transcriptional co-activation.

Gardini A, Baillat D, Cesaroni M, Shiekhattar R.

EMBO J. 2014 Apr 16;33(8):890-905. doi: 10.1002/embj.201385567. Erratum in: EMBO J. 2014 Sep 17;33(18):2134.


Where long noncoding RNAs meet DNA methylation.

Lai F, Shiekhattar R.

Cell Res. 2014 Mar;24(3):263-4. doi: 10.1038/cr.2014.13.


Enhancer RNAs: the new molecules of transcription.

Lai F, Shiekhattar R.

Curr Opin Genet Dev. 2014 Apr;25:38-42. doi: 10.1016/j.gde.2013.11.017. Review.


PINTing for p53.

Shiekhattar R.

Genome Biol. 2013;14(9):132.


Opening the Chromatin by eRNAs.

Shiekhattar R.

Mol Cell. 2013 Sep 12;51(5):557-8. doi: 10.1016/j.molcel.2013.08.033.


Long noncoding RNAs usher in a new era in the biology of enhancers.

├śrom UA, Shiekhattar R.

Cell. 2013 Sep 12;154(6):1190-3. doi: 10.1016/j.cell.2013.08.028. Review.

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