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Items: 1 to 20 of 58

1.

Mutational processes shape the landscape of TP53 mutations in human cancer.

Giacomelli AO, Yang X, Lintner RE, McFarland JM, Duby M, Kim J, Howard TP, Takeda DY, Ly SH, Kim E, Gannon HS, Hurhula B, Sharpe T, Goodale A, Fritchman B, Steelman S, Vazquez F, Tsherniak A, Aguirre AJ, Doench JG, Piccioni F, Roberts CWM, Meyerson M, Getz G, Johannessen CM, Root DE, Hahn WC.

Nat Genet. 2018 Sep 17. doi: 10.1038/s41588-018-0204-y. [Epub ahead of print]

PMID:
30224644
2.

Phase-stable, downconverting, microwave photonic link with analysis of balanced heterodyne detection intermodulation.

Harrington C, Sharpe T, Dahl J, Barber ZW.

Appl Opt. 2018 Jul 1;57(19):5273-5280. doi: 10.1364/AO.57.005273.

PMID:
30117820
3.

GATK PathSeq: A customizable computational tool for the discovery and identification of microbial sequences in libraries from eukaryotic hosts.

Walker MA, Pedamallu CS, Ojesina AI, Bullman S, Sharpe T, Whelan CW, Meyerson M.

Bioinformatics. 2018 Jul 4. doi: 10.1093/bioinformatics/bty501. [Epub ahead of print]

PMID:
29982281
4.

KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists.

Zihlmann P, Silbermann M, Sharpe T, Jiang X, Mühlethaler T, Jakob RP, Rabbani S, Sager CP, Frei P, Pang L, Maier T, Ernst B.

Chemistry. 2018 Sep 3;24(49):13049-13057. doi: 10.1002/chem.201802599. Epub 2018 Jul 27.

PMID:
29939458
5.

Mutant Variants of the Substrate-Binding Protein DppA from Escherichia coli Enhance Growth on Nonstandard γ-Glutamyl Amide-Containing Peptides.

Kuenzl T, Li-Blatter X, Srivastava P, Herdewijn P, Sharpe T, Panke S.

Appl Environ Microbiol. 2018 Jun 18;84(13). pii: e00340-18. doi: 10.1128/AEM.00340-18. Print 2018 Jul 1.

PMID:
29728377
6.

SvABA: genome-wide detection of structural variants and indels by local assembly.

Wala JA, Bandopadhayay P, Greenwald NF, O'Rourke R, Sharpe T, Stewart C, Schumacher S, Li Y, Weischenfeldt J, Yao X, Nusbaum C, Campbell P, Getz G, Meyerson M, Zhang CZ, Imielinski M, Beroukhim R.

Genome Res. 2018 Apr;28(4):581-591. doi: 10.1101/gr.221028.117. Epub 2018 Mar 13.

PMID:
29535149
7.

The dynamic dimer structure of the chaperone Trigger Factor.

Morgado L, Burmann BM, Sharpe T, Mazur A, Hiller S.

Nat Commun. 2017 Dec 8;8(1):1992. doi: 10.1038/s41467-017-02196-7.

8.

Psychotic Experiences in the Context of Police Victimization: Data From the Survey of Police-Public Encounters.

DeVylder JE, Cogburn C, Oh HY, Anglin D, Smith ME, Sharpe T, Jun HJ, Schiffman J, Lukens E, Link B.

Schizophr Bull. 2017 Sep 1;43(5):993-1001. doi: 10.1093/schbul/sbx038.

9.

A molecular mechanism of chaperone-client recognition.

He L, Sharpe T, Mazur A, Hiller S.

Sci Adv. 2016 Nov 16;2(11):e1601625. doi: 10.1126/sciadv.1601625. eCollection 2016 Nov.

10.

Syrosingopine sensitizes cancer cells to killing by metformin.

Benjamin D, Colombi M, Hindupur SK, Betz C, Lane HA, El-Shemerly MY, Lu M, Quagliata L, Terracciano L, Moes S, Sharpe T, Wodnar-Filipowicz A, Moroni C, Hall MN.

Sci Adv. 2016 Dec 23;2(12):e1601756. doi: 10.1126/sciadv.1601756. eCollection 2016 Dec.

11.

Use of the UKHCDO Database for a postmarketing surveillance study of different doses of recombinant factor VIIa in haemophilia.

Hay CRM, Sharpe T, Dolan G; UKHCDO.

Haemophilia. 2017 May;23(3):376-382. doi: 10.1111/hae.13139. Epub 2016 Dec 27.

PMID:
28026073
12.

Prospective functional classification of all possible missense variants in PPARG.

Majithia AR, Tsuda B, Agostini M, Gnanapradeepan K, Rice R, Peloso G, Patel KA, Zhang X, Broekema MF, Patterson N, Duby M, Sharpe T, Kalkhoven E, Rosen ED, Barroso I, Ellard S; UK Monogenic Diabetes Consortium, Kathiresan S; Myocardial Infarction Genetics Consortium, O'Rahilly S; UK Congenital Lipodystrophy Consortium, Chatterjee K, Florez JC, Mikkelsen T, Savage DB, Altshuler D.

Nat Genet. 2016 Dec;48(12):1570-1575. doi: 10.1038/ng.3700. Epub 2016 Oct 17.

13.

Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.

Moschetti T, Sharpe T, Fischer G, Marsh ME, Ng HK, Morgan M, Scott DE, Blundell TL, R Venkitaraman A, Skidmore J, Abell C, Hyvönen M.

J Mol Biol. 2016 Nov 20;428(23):4589-4607. doi: 10.1016/j.jmb.2016.10.009. Epub 2016 Oct 8.

14.

Risk factors for recurrent violent injury among black men.

Richardson JB, St Vil C, Sharpe T, Wagner M, Cooper C.

J Surg Res. 2016 Jul;204(1):261-6. doi: 10.1016/j.jss.2016.04.027. Epub 2016 Apr 25.

PMID:
27451895
15.

Effect of flip-flops on lower limb kinematics during walking: a cross-sectional study using three-dimensional gait analysis.

Sharpe T, Malone A, French H, Kiernan D, O'Brien T.

Ir J Med Sci. 2016 May;185(2):493-501. doi: 10.1007/s11845-016-1421-y. Epub 2016 Feb 22.

PMID:
26902474
16.

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification.

Stanger FV, Burmann BM, Harms A, Aragão H, Mazur A, Sharpe T, Dehio C, Hiller S, Schirmer T.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E529-37. doi: 10.1073/pnas.1516930113. Epub 2016 Jan 19.

17.

Disinfectant wipes are appropriate to control microbial bioburden from surfaces: use of a new ASTM standard test protocol to demonstrate efficacy.

Sattar SA, Bradley C, Kibbee R, Wesgate R, Wilkinson MA, Sharpe T, Maillard JY.

J Hosp Infect. 2015 Dec;91(4):319-25. doi: 10.1016/j.jhin.2015.08.026. Epub 2015 Oct 9.

PMID:
26518272
18.

Occupant Interactions and Effectiveness of Natural Ventilation Strategies in Contemporary New Housing in Scotland, UK.

Sharpe T, Farren P, Howieson S, Tuohy P, McQuillan J.

Int J Environ Res Public Health. 2015 Jul 21;12(7):8480-97. doi: 10.3390/ijerph120708480.

19.

FimH antagonists: bioisosteres to improve the in vitro and in vivo PK/PD profile.

Kleeb S, Pang L, Mayer K, Eris D, Sigl A, Preston RC, Zihlmann P, Sharpe T, Jakob RP, Abgottspon D, Hutter AS, Scharenberg M, Jiang X, Navarra G, Rabbani S, Smiesko M, Lüdin N, Bezençon J, Schwardt O, Maier T, Ernst B.

J Med Chem. 2015 Mar 12;58(5):2221-39. doi: 10.1021/jm501524q. Epub 2015 Feb 20.

PMID:
25666045
20.

Geology. The birth of the geological map.

Sharpe T.

Science. 2015 Jan 16;347(6219):230-2. doi: 10.1126/science.aaa2330. No abstract available.

PMID:
25593171

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