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Virus-Like Particles as Carrier Systems to Enhance Immunomodulation in Allergen Immunotherapy.

Anzaghe M, Schülke S, Scheurer S.

Curr Allergy Asthma Rep. 2018 Oct 25;18(12):71. doi: 10.1007/s11882-018-0827-1. Review.


Identification and molecular characterization of allergenic non-specific lipid-transfer protein from durum wheat (Triticum turgidum).

Safi H, Wangorsch A, Lidholm J, Brini F, Spiric J, Rihs HP, Vieths S, Armentia A, Farioli L, Diaz-Perales A, Pastorello EA, Scheurer S.

Clin Exp Allergy. 2018 Sep 10. doi: 10.1111/cea.13271. [Epub ahead of print]


Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice.

Rodriguez MJ, Wangorsch A, Gomez F, Schülke S, Torres MJ, Vieths S, Scheurer S, Toda M, Mayorga C.

J Immunol Res. 2018 Jun 13;2018:3479185. doi: 10.1155/2018/3479185. eCollection 2018.


Interaction of Non-Specific Lipid-Transfer Proteins With Plant-Derived Lipids and Its Impact on Allergic Sensitization.

Scheurer S, Schülke S.

Front Immunol. 2018 Jun 20;9:1389. doi: 10.3389/fimmu.2018.01389. eCollection 2018. Review.


Modular MLV-VLPs co-displaying ovalbumin peptides and GM-CSF effectively induce expansion of CD11b+ APC and antigen-specific T cell responses in vitro.

Gogesch P, Schülke S, Scheurer S, Mühlebach MD, Waibler Z.

Mol Immunol. 2018 Sep;101:19-28. doi: 10.1016/j.molimm.2018.05.017. Epub 2018 May 28.


Author Correction: Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo.

Schülke S, Kuttich K, Wolfheimer S, Duschek N, Wangorsch A, Reuter A, Briza P, Pablos I, Gadermaier G, Ferreira F, Vieths S, Toda M, Scheurer S.

Sci Rep. 2018 Feb 6;8(1):2745. doi: 10.1038/s41598-018-20635-3.


Targeting of Immune Cells by Dual TLR2/7 Ligands Suppresses Features of Allergic Th2 Immune Responses in Mice.

Laiño J, Wangorsch A, Blanco F, Wolfheimer S, Krause M, Flaczyk A, Möller TM, Tsai M, Galli S, Vieths S, Toda M, Scheurer S, Schülke S.

J Immunol Res. 2017;2017:7983217. doi: 10.1155/2017/7983217. Epub 2017 Oct 24.


Epicutaneous immunotherapy.

Scheurer S, Toda M.

Allergol Immunopathol (Madr). 2017 Dec;45 Suppl 1:25-29. doi: 10.1016/j.aller.2017.09.007. Epub 2017 Nov 3. Review. No abstract available.


Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo.

Schülke S, Kuttich K, Wolfheimer S, Duschek N, Wangorsch A, Reuter A, Briza P, Pablos I, Gadermaier G, Ferreira F, Vieths S, Toda M, Scheurer S.

Sci Rep. 2017 Sep 18;7(1):11782. doi: 10.1038/s41598-017-11972-w. Erratum in: Sci Rep. 2018 Feb 6;8(1):2745.


Critical role of mammalian target of rapamycin for IL-10 dendritic cell induction by a flagellin A conjugate in preventing allergic sensitization.

Schülke S, Fiedler AH, Junker AC, Flaczyk A, Wolfheimer S, Wangorsch A, Heinz A, Beckert H, Nagl B, Bohle B, Vieths S, Toda M, Scheurer S.

J Allergy Clin Immunol. 2018 May;141(5):1786-1798.e11. doi: 10.1016/j.jaci.2017.07.002. Epub 2017 Sep 5.


Cell-permeable capsids as universal antigen carrier for the induction of an antigen-specific CD8+ T-cell response.

Akhras S, Toda M, Boller K, Himmelsbach K, Elgner F, Biehl M, Scheurer S, Gratz M, Vieths S, Hildt E.

Sci Rep. 2017 Aug 29;7(1):9630. doi: 10.1038/s41598-017-08787-0.


Identification and implication of an allergenic PR-10 protein from walnut in birch pollen associated walnut allergy.

Wangorsch A, Jamin A, Lidholm J, Gräni N, Lang C, Ballmer-Weber B, Vieths S, Scheurer S.

Mol Nutr Food Res. 2017 Apr;61(4). doi: 10.1002/mnfr.201600902. Epub 2017 Feb 10.


A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro.

Schülke S, Vogel L, Junker AC, Hanschmann KM, Flaczyk A, Vieths S, Scheurer S.

J Immunol Res. 2016;2016:4156456. doi: 10.1155/2016/4156456. Epub 2016 Jun 1.


[Immunological background and pathomechanisms of food allergies].

Schülke S, Scheurer S.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Jun;59(6):723-31. doi: 10.1007/s00103-016-2346-3. Review. German.


Molecular cloning of plane pollen allergen Pla a 3 and its utility as diagnostic marker for peach associated plane pollen allergy.

Wangorsch A, Larsson H, Messmer M, García-Moral A, Lauer I, Wolfheimer S, Schülke S, Bartra J, Vieths S, Lidholm J, Scheurer S.

Clin Exp Allergy. 2016 May;46(5):764-74. doi: 10.1111/cea.12721.


Epicutaneous immunotherapy with a hypoallergenic Bet v 1 suppresses allergic asthma in a murine model.

Siebeneicher S, Reuter S, Wangorsch A, Krause M, Foetisch K, Heinz A, Naito S, Reuter A, Taube C, Vieths S, Scheurer S, Toda M.

Allergy. 2015 Dec;70(12):1559-68. doi: 10.1111/all.12732. Epub 2015 Sep 25.


Lentiviral Protein Transfer Vectors Are an Efficient Vaccine Platform and Induce a Strong Antigen-Specific Cytotoxic T Cell Response.

Uhlig KM, Schülke S, Scheuplein VA, Malczyk AH, Reusch J, Kugelmann S, Muth A, Koch V, Hutzler S, Bodmer BS, Schambach A, Buchholz CJ, Waibler Z, Scheurer S, Mühlebach MD.

J Virol. 2015 Sep;89(17):9044-60. doi: 10.1128/JVI.00844-15. Epub 2015 Jun 17.


MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison with LPS.

Schülke S, Flaczyk A, Vogel L, Gaudenzio N, Angers I, Löschner B, Wolfheimer S, Spreitzer I, Qureshi S, Tsai M, Galli S, Vieths S, Scheurer S.

Allergy. 2015 Oct;70(10):1259-68. doi: 10.1111/all.12675. Epub 2015 Jul 8.


Food allergens: molecular and immunological aspects, allergen databases and cross-reactivity.

Lorenz AR, Scheurer S, Vieths S.

Chem Immunol Allergy. 2015;101:18-29. doi: 10.1159/000371647. Epub 2015 May 21.


What makes an allergen?

Scheurer S, Toda M, Vieths S.

Clin Exp Allergy. 2015 Jul;45(7):1150-61. doi: 10.1111/cea.12571. Review.


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