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Items: 1 to 20 of 110

1.

Machine Learning Driven Analysis of Large Scale Simulations Reveals Conformational Characteristics of Ubiquitin Chains.

Berg A, Franke L, Scheffner M, Peter C.

J Chem Theory Comput. 2020 Mar 20. doi: 10.1021/acs.jctc.0c00045. [Epub ahead of print]

PMID:
32196332
2.

Novel fluorescently labelled ATP analogues for direct monitoring of ubiquitin activation.

Marx A, Hammler D, Stuber K, Offensperger F, Scheffner M, Zumbusch A.

Chemistry. 2020 Mar 10. doi: 10.1002/chem.202001091. [Epub ahead of print]

PMID:
32154932
3.

Assembly of branched ubiquitin oligomers by click chemistry.

Zhao X, Scheffner M, Marx A.

Chem Commun (Camb). 2019 Oct 29;55(87):13093-13095. doi: 10.1039/c9cc07303e.

PMID:
31612161
4.

Effects of the antifungal agent ciclopirox in HPV-positive cancer cells: Repression of viral E6/E7 oncogene expression and induction of senescence and apoptosis.

Braun JA, Herrmann AL, Blase JI, Frensemeier K, Bulkescher J, Scheffner M, Galy B, Hoppe-Seyler K, Hoppe-Seyler F.

Int J Cancer. 2020 Jan 15;146(2):461-474. doi: 10.1002/ijc.32709. Epub 2019 Oct 31.

PMID:
31603527
5.

Formation of the Alarmones Diadenosine Triphosphate and Tetraphosphate by Ubiquitin- and Ubiquitin-like-Activating Enzymes.

Götz KH, Mex M, Stuber K, Offensperger F, Scheffner M, Marx A.

Cell Chem Biol. 2019 Nov 21;26(11):1535-1543.e5. doi: 10.1016/j.chembiol.2019.08.004. Epub 2019 Sep 3.

PMID:
31492597
6.

Artificially Linked Ubiquitin Dimers Characterised Structurally and Dynamically by NMR Spectroscopy.

Zhao X, Mißun M, Schneider T, Müller F, Lutz J, Scheffner M, Marx A, Kovermann M.

Chembiochem. 2019 Jul 15;20(14):1772-1777. doi: 10.1002/cbic.201900146. Epub 2019 Jun 24.

7.

On Biomineralization: Enzymes Switch on Mesocrystal Assembly.

Rao A, Roncal-Herrero T, Schmid E, Drechsler M, Scheffner M, Gebauer D, Kröger R, Cölfen H.

ACS Cent Sci. 2019 Feb 27;5(2):357-364. doi: 10.1021/acscentsci.8b00853. Epub 2019 Feb 1.

8.

Towards a molecular basis of ubiquitin signaling: A dual-scale simulation study of ubiquitin dimers.

Berg A, Kukharenko O, Scheffner M, Peter C.

PLoS Comput Biol. 2018 Nov 16;14(11):e1006589. doi: 10.1371/journal.pcbi.1006589. eCollection 2018 Nov.

9.

Structural dynamics of the E6AP/UBE3A-E6-p53 enzyme-substrate complex.

Sailer C, Offensperger F, Julier A, Kammer KM, Walker-Gray R, Gold MG, Scheffner M, Stengel F.

Nat Commun. 2018 Oct 25;9(1):4441. doi: 10.1038/s41467-018-06953-0.

10.

Identification of Proteins Interacting with Ubiquitin Chains.

Zhao X, Lutz J, Höllmüller E, Scheffner M, Marx A, Stengel F.

Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15764-15768. doi: 10.1002/anie.201705898. Epub 2017 Nov 7.

PMID:
29045006
11.

Small-Molecule Inhibitors of the Tumor Suppressor Fhit.

Lange S, Hacker SM, Schmid P, Scheffner M, Marx A.

Chembiochem. 2017 Sep 5;18(17):1707-1711. doi: 10.1002/cbic.201700226. Epub 2017 Jul 20.

PMID:
28643453
12.

Different Enzymatic Processing of γ-Phosphoramidate and γ-Phosphoester-Modified ATP Analogues.

Ermert S, Hacker SM, Buntru A, Scheffner M, Hauck CR, Marx A.

Chembiochem. 2017 Feb 16;18(4):378-381. doi: 10.1002/cbic.201600590. Epub 2017 Jan 10.

PMID:
27935244
13.

Anionic surfactants enhance click reaction-mediated protein conjugation with ubiquitin.

Schneider D, Schneider T, Aschenbrenner J, Mortensen F, Scheffner M, Marx A.

Bioorg Med Chem. 2016 Mar 1;24(5):995-1001. doi: 10.1016/j.bmc.2016.01.027. Epub 2016 Jan 16.

PMID:
26827138
14.

Click chemistry for targeted protein ubiquitylation and ubiquitin chain formation.

Rösner D, Schneider T, Schneider D, Scheffner M, Marx A.

Nat Protoc. 2015 Oct;10(10):1594-611. doi: 10.1038/nprot.2015.106. Epub 2015 Sep 24.

PMID:
26401915
15.

Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination.

Mortensen F, Schneider D, Barbic T, Sladewska-Marquardt A, Kühnle S, Marx A, Scheffner M.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9872-7. doi: 10.1073/pnas.1505923112. Epub 2015 Jul 27.

16.

Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells.

Honegger A, Schilling D, Bastian S, Sponagel J, Kuryshev V, Sültmann H, Scheffner M, Hoppe-Seyler K, Hoppe-Seyler F.

PLoS Pathog. 2015 Mar 11;11(3):e1004712. doi: 10.1371/journal.ppat.1004712. eCollection 2015 Mar.

17.

Dissecting ubiquitin signaling with linkage-defined and protease resistant ubiquitin chains.

Schneider T, Schneider D, Rösner D, Malhotra S, Mortensen F, Mayer TU, Scheffner M, Marx A.

Angew Chem Int Ed Engl. 2014 Nov 17;53(47):12925-9. doi: 10.1002/anie.201407192. Epub 2014 Sep 4.

PMID:
25196034
18.

Selective monitoring of the enzymatic activity of the tumor suppressor Fhit.

Hacker SM, Mortensen F, Scheffner M, Marx A.

Angew Chem Int Ed Engl. 2014 Sep 15;53(38):10247-50. doi: 10.1002/anie.201405259. Epub 2014 Aug 5.

PMID:
25098403
19.

Poly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function.

Fischer JM, Popp O, Gebhard D, Veith S, Fischbach A, Beneke S, Leitenstorfer A, Bergemann J, Scheffner M, Ferrando-May E, Mangerich A, Bürkle A.

FEBS J. 2014 Aug;281(16):3625-41. doi: 10.1111/febs.12885. Epub 2014 Jul 21.

20.

Fluorogenic ATP analogues for online monitoring of ATP consumption: observing ubiquitin activation in real time.

Hacker SM, Pagliarini D, Tischer T, Hardt N, Schneider D, Mex M, Mayer TU, Scheffner M, Marx A.

Angew Chem Int Ed Engl. 2013 Nov 4;52(45):11916-9. doi: 10.1002/anie.201304723. Epub 2013 Sep 17. No abstract available.

PMID:
24105922

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