Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 61

1.

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.

Mitchell SJ, Bernier M, Aon MA, Cortassa S, Kim EY, Fang EF, Palacios HH, Ali A, Navas-Enamorado I, Di Francesco A, Kaiser TA, Waltz TB, Zhang N, Ellis JL, Elliott PJ, Frederick DW, Bohr VA, Schmidt MS, Brenner C, Sinclair DA, Sauve AA, Baur JA, de Cabo R.

Cell Metab. 2018 Mar 6;27(3):667-676.e4. doi: 10.1016/j.cmet.2018.02.001.

PMID:
29514072
2.

Regulatory Effects of NAD+ Metabolic Pathways on Sirtuin Activity.

Zhang N, Sauve AA.

Prog Mol Biol Transl Sci. 2018;154:71-104. doi: 10.1016/bs.pmbts.2017.11.012.

PMID:
29413178
3.

Synthesis of β-Nicotinamide Riboside Using an Efficient Two-Step Methodology.

Zhang N, Sauve AA.

Curr Protoc Nucleic Acid Chem. 2017 Dec 24;71:14.14.1-14.14.9. doi: 10.1002/cpnc.43.

PMID:
29275540
4.

NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.

Ryu D, Zhang H, Ropelle ER, Sorrentino V, Mázala DA, Mouchiroud L, Marshall PL, Campbell MD, Ali AS, Knowels GM, Bellemin S, Iyer SR, Wang X, Gariani K, Sauve AA, Cantó C, Conley KE, Walter L, Lovering RM, Chin ER, Jasmin BJ, Marcinek DJ, Menzies KJ, Auwerx J.

Sci Transl Med. 2016 Oct 19;8(361):361ra139.

5.

NAD(+) metabolism: Bioenergetics, signaling and manipulation for therapy.

Yang Y, Sauve AA.

Biochim Biophys Acta. 2016 Dec;1864(12):1787-1800. doi: 10.1016/j.bbapap.2016.06.014. Epub 2016 Jun 29. Review.

6.

Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects.

Traba J, Kwarteng-Siaw M, Okoli TC, Li J, Huffstutler RD, Bray A, Waclawiw MA, Han K, Pelletier M, Sauve AA, Siegel RM, Sack MN.

J Clin Invest. 2015 Nov 3;125(12):4592-600. doi: 10.1172/JCI83260.

7.

Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart.

Xu W, Barrientos T, Mao L, Rockman HA, Sauve AA, Andrews NC.

Cell Rep. 2015 Oct 20;13(3):533-545. doi: 10.1016/j.celrep.2015.09.023. Epub 2015 Oct 8.

8.

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.

Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku CS, Koo SI, Fomitchova A, Cantó C, Schoonjans K, Sauve AA, Lee JY, Auwerx J.

Hepatology. 2016 Apr;63(4):1190-204. doi: 10.1002/hep.28245. Epub 2015 Dec 16.

9.

NAD⁺ content and its role in mitochondria.

Li W, Sauve AA.

Methods Mol Biol. 2015;1241:39-48. doi: 10.1007/978-1-4939-1875-1_4.

PMID:
25308486
10.

Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells.

Tian L, Wang C, Hagen FK, Gormley M, Addya S, Soccio R, Casimiro MC, Zhou J, Powell MJ, Xu P, Deng H, Sauve AA, Pestell RG.

Oncotarget. 2014 Sep 15;5(17):7303-15.

11.

Multifunctionalization of cetuximab with bioorthogonal chemistries and parallel EGFR profiling of cell-lines using imaging, FACS and immunoprecipitation approaches.

Reschke ML, Uprety R, Bodhinayake I, Banu M, Boockvar JA, Sauve AA.

Biochim Biophys Acta. 2014 Dec;1844(12):2182-92. doi: 10.1016/j.bbapap.2014.07.017. Epub 2014 Aug 1.

PMID:
25091197
12.

Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets.

Apontes P, Liu Z, Su K, Benard O, Youn DY, Li X, Li W, Mirza RH, Bastie CC, Jelicks LA, Pessin JE, Muzumdar RH, Sauve AA, Chi Y.

Diabetes. 2014 Nov;63(11):3626-36. doi: 10.2337/db14-0006. Epub 2014 May 21.

13.

SIRT2 induces the checkpoint kinase BubR1 to increase lifespan.

North BJ, Rosenberg MA, Jeganathan KB, Hafner AV, Michan S, Dai J, Baker DJ, Cen Y, Wu LE, Sauve AA, van Deursen JM, Rosenzweig A, Sinclair DA.

EMBO J. 2014 Jul 1;33(13):1438-53. doi: 10.15252/embj.201386907. Epub 2014 May 12.

14.

NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease.

Cerutti R, Pirinen E, Lamperti C, Marchet S, Sauve AA, Li W, Leoni V, Schon EA, Dantzer F, Auwerx J, Viscomi C, Zeviani M.

Cell Metab. 2014 Jun 3;19(6):1042-9. doi: 10.1016/j.cmet.2014.04.001. Epub 2014 May 8.

15.

Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.

Pirinen E, Cantó C, Jo YS, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K, Auwerx J.

Cell Metab. 2014 Jun 3;19(6):1034-41. doi: 10.1016/j.cmet.2014.04.002. Epub 2014 May 8.

16.

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB.

Nature. 2014 Apr 10;508(7495):258-62. doi: 10.1038/nature13198.

17.

Dual mode action of mangiferin in mouse liver under high fat diet.

Lim J, Liu Z, Apontes P, Feng D, Pessin JE, Sauve AA, Angeletti RH, Chi Y.

PLoS One. 2014 Mar 5;9(3):e90137. doi: 10.1371/journal.pone.0090137. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e100170.

18.

Nicotinamide riboside, a trace nutrient in foods, is a vitamin B3 with effects on energy metabolism and neuroprotection.

Chi Y, Sauve AA.

Curr Opin Clin Nutr Metab Care. 2013 Nov;16(6):657-61. doi: 10.1097/MCO.0b013e32836510c0. Review.

PMID:
24071780
19.

SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation.

Laurent G, de Boer VC, Finley LW, Sweeney M, Lu H, Schug TT, Cen Y, Jeong SM, Li X, Sauve AA, Haigis MC.

Mol Cell Biol. 2013 Nov;33(22):4552-61. doi: 10.1128/MCB.00087-13. Epub 2013 Sep 16.

20.

Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.

Cantó C, Sauve AA, Bai P.

Mol Aspects Med. 2013 Dec;34(6):1168-201. doi: 10.1016/j.mam.2013.01.004. Epub 2013 Jan 25. Review.

Supplemental Content

Loading ...
Support Center