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Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response.

Uchimura Y, Fuhrer T, Li H, Lawson MA, Zimmermann M, Yilmaz B, Zindel J, Ronchi F, Sorribas M, Hapfelmeier S, Ganal-Vonarburg SC, Gomez de Agüero M, McCoy KD, Sauer U, Macpherson AJ.

Immunity. 2018 Aug 31. pii: S1074-7613(18)30344-3. doi: 10.1016/j.immuni.2018.08.004. [Epub ahead of print]


Capacity for instantaneous catabolism of preferred and non-preferred carbon sources in Escherichia coli and Bacillus subtilis.

Buffing MF, Link H, Christodoulou D, Sauer U.

Sci Rep. 2018 Aug 6;8(1):11760. doi: 10.1038/s41598-018-30266-3.


Moving towards same-day provision of Level 3 care in sexual and reproductive health services.

Sauer U, Mann S, Stephenson JM.

BMJ Sex Reprod Health. 2018 Feb 26. pii: jfprhc-2017-101817. doi: 10.1136/bmjsrh-2017-101817. [Epub ahead of print] No abstract available.


Concepts and applications of foliar spray for microbial inoculants.

Preininger C, Sauer U, Bejarano A, Berninger T.

Appl Microbiol Biotechnol. 2018 Sep;102(17):7265-7282. doi: 10.1007/s00253-018-9173-4. Epub 2018 Jun 30. Review.


Reserve Flux Capacity in the Pentose Phosphate Pathway Enables Escherichia coli's Rapid Response to Oxidative Stress.

Christodoulou D, Link H, Fuhrer T, Kochanowski K, Gerosa L, Sauer U.

Cell Syst. 2018 May 23;6(5):569-578.e7. doi: 10.1016/j.cels.2018.04.009. Epub 2018 May 9.


Modulation of bacterial metabolism by the microenvironment controls MAIT cell stimulation.

Schmaler M, Colone A, Spagnuolo J, Zimmermann M, Lepore M, Kalinichenko A, Bhatia S, Cottier F, Rutishauser T, Pavelka N, Egli A, Azzali E, Pieroni M, Costantino G, Hruz P, Sauer U, Mori L, De Libero G.

Mucosal Immunol. 2018 Jul;11(4):1060-1070. doi: 10.1038/s41385-018-0020-9. Epub 2018 May 9.


High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds.

Zampieri M, Szappanos B, Buchieri MV, Trauner A, Piazza I, Picotti P, Gagneux S, Borrell S, Gicquel B, Lelievre J, Papp B, Sauer U.

Sci Transl Med. 2018 Feb 21;10(429). pii: eaal3973. doi: 10.1126/scitranslmed.aal3973.


Application of open-path Fourier transform infrared spectroscopy for atmospheric monitoring of a CO2 back-production experiment at the Ketzin pilot site (Germany).

Sauer U, Borsdorf H, Dietrich P, Liebscher A, Möller I, Martens S, Möller F, Schlömer S, Schütze C.

Environ Monit Assess. 2018 Feb 3;190(3):114. doi: 10.1007/s10661-018-6488-7.


Investigating Colorimetric Protein Array Assay Schemes for Detection of Recurrence of Bladder Cancer.

Gogalic S, Sauer U, Doppler S, Preininger C.

Biosensors (Basel). 2018 Jan 24;8(1). pii: E10. doi: 10.3390/bios8010010.


A Map of Protein-Metabolite Interactions Reveals Principles of Chemical Communication.

Piazza I, Kochanowski K, Cappelletti V, Fuhrer T, Noor E, Sauer U, Picotti P.

Cell. 2018 Jan 11;172(1-2):358-372.e23. doi: 10.1016/j.cell.2017.12.006. Epub 2018 Jan 4.


Disentangling metabolic functions of bacteria in the honey bee gut.

Kešnerová L, Mars RAT, Ellegaard KM, Troilo M, Sauer U, Engel P.

PLoS Biol. 2017 Dec 12;15(12):e2003467. doi: 10.1371/journal.pbio.2003467. eCollection 2017 Dec.


Systems Pharmacology Dissection of Cholesterol Regulation Reveals Determinants of Large Pharmacodynamic Variability between Cell Lines.

Blattmann P, Henriques D, Zimmermann M, Frommelt F, Sauer U, Saez-Rodriguez J, Aebersold R.

Cell Syst. 2017 Dec 27;5(6):604-619.e7. doi: 10.1016/j.cels.2017.11.002. Epub 2017 Dec 6.


Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow.

Ponomarova O, Gabrielli N, Sévin DC, Mülleder M, Zirngibl K, Bulyha K, Andrejev S, Kafkia E, Typas A, Sauer U, Ralser M, Patil KR.

Cell Syst. 2017 Oct 25;5(4):345-357.e6. doi: 10.1016/j.cels.2017.09.002. Epub 2017 Sep 27.


Genome-Scale Architecture of Small Molecule Regulatory Networks and the Fundamental Trade-Off between Regulation and Enzymatic Activity.

Reznik E, Christodoulou D, Goldford JE, Briars E, Sauer U, Segrè D, Noor E.

Cell Rep. 2017 Sep 12;20(11):2666-2677. doi: 10.1016/j.celrep.2017.08.066.


Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of Mycobacterium tuberculosis during Early Macrophage Infection.

Zimmermann M, Kogadeeva M, Gengenbacher M, McEwen G, Mollenkopf HJ, Zamboni N, Kaufmann SHE, Sauer U.

mSystems. 2017 Aug 22;2(4). pii: e00057-17. doi: 10.1128/mSystems.00057-17. eCollection 2017 Jul-Aug.


Towards detecting regulatory protein-metabolite interactions.

Diether M, Sauer U.

Curr Opin Microbiol. 2017 Oct;39:16-23. doi: 10.1016/j.mib.2017.07.006. Epub 2017 Aug 12. Review.


Design and development of a workflow for microbial spray formulations including decision criteria.

Bejarano A, Sauer U, Preininger C.

Appl Microbiol Biotechnol. 2017 Oct;101(19):7335-7346. doi: 10.1007/s00253-017-8447-6. Epub 2017 Aug 8.


A Chip for Estrogen Receptor Action: Detection of Biomarkers Released by MCF-7 Cells through Estrogenic and Anti-Estrogenic Effects.

Gier K, Preininger C, Sauer U.

Sensors (Basel). 2017 Aug 1;17(8). pii: E1760. doi: 10.3390/s17081760.


PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis.

Rieck B, Degiacomi G, Zimmermann M, Cascioferro A, Boldrin F, Lazar-Adler NR, Bottrill AR, le Chevalier F, Frigui W, Bellinzoni M, Lisa MN, Alzari PM, Nguyen L, Brosch R, Sauer U, Manganelli R, O'Hare HM.

PLoS Pathog. 2017 May 17;13(5):e1006399. doi: 10.1371/journal.ppat.1006399. eCollection 2017 May.


Nontargeted Metabolomics Reveals the Multilevel Response to Antibiotic Perturbations.

Zampieri M, Zimmermann M, Claassen M, Sauer U.

Cell Rep. 2017 May 9;19(6):1214-1228. doi: 10.1016/j.celrep.2017.04.002.

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