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Items: 1 to 20 of 234

1.

Repurposing of Drugs Targeting YAP-TEAD Functions.

Elisi GM, Santucci M, D'Arca D, Lauriola A, Marverti G, Losi L, Scalvini L, Bolognesi ML, Mor M, Costi MP.

Cancers (Basel). 2018 Sep 14;10(9). pii: E329. doi: 10.3390/cancers10090329. Review.

2.

Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth.

Saxena P, Severi L, Santucci M, Taddia L, Ferrari S, Luciani R, Marverti G, Marraccini C, Tondi D, Mor M, Scalvini L, Vitiello S, Losi L, Fonda S, Pacifico S, Guerrini R, D'Arca D, Ponterini G, Costi MP.

J Med Chem. 2018 Aug 23;61(16):7374-7380. doi: 10.1021/acs.jmedchem.7b01699. Epub 2018 Aug 13.

PMID:
30035541
3.

Effect of valproic acid on perampanel pharmacokinetics in patients with epilepsy.

Contin M, Bisulli F, Santucci M, Riva R, Tonon F, Mohamed S, Ferri L, Stipa C, Tinuper P; Perampanel Study Group.

Epilepsia. 2018 Jul;59(7):e103-e108. doi: 10.1111/epi.14446. Epub 2018 Jun 13.

PMID:
29897632
4.

Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR).

Francesconi V, Giovannini L, Santucci M, Cichero E, Costi MP, Naesens L, Giordanetto F, Tonelli M.

Eur J Med Chem. 2018 Jul 15;155:229-243. doi: 10.1016/j.ejmech.2018.05.059. Epub 2018 Jun 2.

PMID:
29886325
5.

Structure-Based Virtual Screening for the Discovery of Novel Inhibitors of New Delhi Metallo-β-lactamase-1.

Spyrakis F, Celenza G, Marcoccia F, Santucci M, Cross S, Bellio P, Cendron L, Perilli M, Tondi D.

ACS Med Chem Lett. 2017 Nov 26;9(1):45-50. doi: 10.1021/acsmedchemlett.7b00428. eCollection 2018 Jan 11.

PMID:
29348810
6.

Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-β-lactamases.

Santucci M, Spyrakis F, Cross S, Quotadamo A, Farina D, Tondi D, De Luca F, Docquier JD, Prieto AI, Ibacache C, Blázquez J, Venturelli A, Cruciani G, Costi MP.

Sci Rep. 2017 Dec 18;7(1):17716. doi: 10.1038/s41598-017-17399-7.

7.

Label-free fiber optic optrode for the detection of class C β-lactamases expressed by drug resistant bacteria.

Zuppolini S, Quero G, Consales M, Diodato L, Vaiano P, Venturelli A, Santucci M, Spyrakis F, Costi MP, Giordano M, Cutolo A, Cusano A, Borriello A.

Biomed Opt Express. 2017 Oct 23;8(11):5191-5205. doi: 10.1364/BOE.8.005191. eCollection 2017 Nov 1.

8.

Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus.

Tonelli M, Naesens L, Gazzarrini S, Santucci M, Cichero E, Tasso B, Moroni A, Costi MP, Loddo R.

Eur J Med Chem. 2017 Jul 28;135:467-478. doi: 10.1016/j.ejmech.2017.04.070. Epub 2017 Apr 27.

PMID:
28477572
9.

Langerhans, plasmacytoid dendritic and myeloid-derived suppressor cell levels in mycosis fungoides vary according to the stage of the disease.

Pileri A, Agostinelli C, Sessa M, Quaglino P, Santucci M, Tomasini C, Grandi V, Fava P, Astrua C, Righi S, Patrizi A, Pileri SA, Pimpinelli N.

Virchows Arch. 2017 May;470(5):575-582. doi: 10.1007/s00428-017-2107-1. Epub 2017 Mar 20.

PMID:
28321511
10.

Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.

Di Pisa F, Landi G, Dello Iacono L, Pozzi C, Borsari C, Ferrari S, Santucci M, Santarem N, Cordeiro-da-Silva A, Moraes CB, Alcantara LM, Fontana V, Freitas-Junior LH, Gul S, Kuzikov M, Behrens B, Pöhner I, Wade RC, Costi MP, Mangani S.

Molecules. 2017 Mar 8;22(3). pii: E426. doi: 10.3390/molecules22030426.

11.

Primary cutaneous B-cell lymphoma other than marginal zone: clinicopathologic analysis of 161 cases: Comparison with current classification and definition of prognostic markers.

Lucioni M, Berti E, Arcaini L, Croci GA, Maffi A, Klersy C, Goteri G, Tomasini C, Quaglino P, Riboni R, Arra M, Dallera E, Grandi V, Alaibac M, Ramponi A, Rattotti S, Cabras MG, Franceschetti S, Fraternali-Orcioni G, Zerbinati N, Onida F, Ascani S, Fierro MT, Rupoli S, Gambacorta M, Zinzani PL, Pimpinelli N, Santucci M, Paulli M.

Cancer Med. 2016 Oct;5(10):2740-2755. doi: 10.1002/cam4.865. Epub 2016 Sep 26.

12.

Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase.

Luciani R, Saxena P, Surade S, Santucci M, Venturelli A, Borsari C, Marverti G, Ponterini G, Ferrari S, Blundell TL, Costi MP.

J Med Chem. 2016 Oct 13;59(19):9269-9275. Epub 2016 Sep 29.

PMID:
27589670
13.

Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology.

Ponterini G, Martello A, Pavesi G, Lauriola A, Luciani R, Santucci M, Pelà M, Gozzi G, Pacifico S, Guerrini R, Marverti G, Costi MP, D'Arca D.

Sci Rep. 2016 Jun 2;6:27198. doi: 10.1038/srep27198.

14.

Extrastriate visual cortex in idiopathic occipital epilepsies: The contribution of retinotopic areas to spike generation.

Meletti S, Ruggieri A, Avanzini P, Caramaschi E, Filippini M, Bergonzini P, Monti G, Vignoli A, Olivotto S, Mastrangelo M, Santucci M, Gobbi G, Veggiotti P, Vaudano AE.

Epilepsia. 2016 Jun;57(6):896-906. doi: 10.1111/epi.13385. Epub 2016 Apr 19.

15.

The syndrome of polymicrogyria, thalamic hypoplasia, and epilepsy with CSWS.

Bartolini E, Falchi M, Zellini F, Parrini E, Grisotto L, Cosottini M, Posar A, Parmeggiani A, Ambrosetto G, Ferrari AR, Santucci M, Salas-Puig J, Barba C, Guerrini R.

Neurology. 2016 Mar 29;86(13):1250-9. doi: 10.1212/WNL.0000000000002526. Epub 2016 Mar 4.

PMID:
26944271
16.

Mutations in the mammalian target of rapamycin pathway regulators NPRL2 and NPRL3 cause focal epilepsy.

Ricos MG, Hodgson BL, Pippucci T, Saidin A, Ong YS, Heron SE, Licchetta L, Bisulli F, Bayly MA, Hughes J, Baldassari S, Palombo F; Epilepsy Electroclinical Study Group, Santucci M, Meletti S, Berkovic SF, Rubboli G, Thomas PQ, Scheffer IE, Tinuper P, Geoghegan J, Schreiber AW, Dibbens LM.

Ann Neurol. 2016 Jan;79(1):120-31. doi: 10.1002/ana.24547. Epub 2015 Dec 12.

PMID:
26505888
17.

Headache in epilepsy: prevalence and clinical features.

Mainieri G, Cevoli S, Giannini G, Zummo L, Leta C, Broli M, Ferri L, Santucci M, Posar A, Avoni P, Cortelli P, Tinuper P, Bisulli F.

J Headache Pain. 2015;16:556. doi: 10.1186/s10194-015-0556-y. Epub 2015 Aug 6.

18.

Histopathological and immunophenotypical criteria for the diagnosis of Sézary syndrome in differentiation from other erythrodermic skin diseases: a European Organisation for Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Task Force Study of 97 cases.

Klemke CD, Booken N, Weiss C, Nicolay JP, Goerdt S, Felcht M, Géraud C, Kempf W, Assaf C, Ortonne N, Battistella M, Bagot M, Knobler R, Quaglino P, Arheiliger B, Santucci M, Jansen P, Vermeer MH, Willemze R.

Br J Dermatol. 2015 Jul;173(1):93-105. doi: 10.1111/bjd.13832. Epub 2015 Jun 23.

19.

The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment.

Santucci M, Vignudelli T, Ferrari S, Mor M, Scalvini L, Bolognesi ML, Uliassi E, Costi MP.

J Med Chem. 2015 Jun 25;58(12):4857-73. doi: 10.1021/jm501615v. Epub 2015 Mar 11. Review.

PMID:
25719868
20.

Intestinal metaplasia of the sinonasal mucosa adjacent to intestinal-type adenocarcinoma. A morphologic, immunohistochemical, and molecular study.

Franchi A, Palomba A, Miligi L, Ranucci V, Innocenti DR, Simoni A, Pepi M, Santucci M.

Virchows Arch. 2015 Feb;466(2):161-8. doi: 10.1007/s00428-014-1696-1. Epub 2014 Nov 28.

PMID:
25431194

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