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Items: 1 to 20 of 222

1.

Local Acetaldehyde-An Essential Role in Alcohol-Related Upper Gastrointestinal Tract Carcinogenesis.

Nieminen MT, Salaspuro M.

Cancers (Basel). 2018 Jan 5;10(1). pii: E11. doi: 10.3390/cancers10010011. Review.

2.

Key role of local acetaldehyde in upper GI tract carcinogenesis.

Salaspuro M.

Best Pract Res Clin Gastroenterol. 2017 Oct;31(5):491-499. doi: 10.1016/j.bpg.2017.09.016. Epub 2017 Sep 23. Review.

PMID:
29195668
3.

ALDH2-deficiency as genetic epidemiologic and biochemical model for the carcinogenicity of acetaldehyde.

Lachenmeier DW, Salaspuro M.

Regul Toxicol Pharmacol. 2017 Jun;86:128-136. doi: 10.1016/j.yrtph.2017.02.024. Epub 2017 Mar 1.

4.

Alcohol, microbiome, life style influence alcohol and non-alcoholic organ damage.

Neuman MG, French SW, Zakhari S, Malnick S, Seitz HK, Cohen LB, Salaspuro M, Voinea-Griffin A, Barasch A, Kirpich IA, Thomes PG, Schrum LW, Donohue TM Jr, Kharbanda KK, Cruz M, Opris M.

Exp Mol Pathol. 2017 Feb;102(1):162-180. doi: 10.1016/j.yexmp.2017.01.003. Epub 2017 Jan 7. Review.

PMID:
28077318
5.

Slow-release L-cysteine capsule prevents gastric mucosa exposure to carcinogenic acetaldehyde: results of a randomised single-blinded, cross-over study of Helicobacter-associated atrophic gastritis.

Hellström PM, Hendolin P, Kaihovaara P, Kronberg L, Meierjohann A, Millerhovf A, Paloheimo L, Sundelin H, Syrjänen K, Webb DL, Salaspuro M.

Scand J Gastroenterol. 2017 Feb;52(2):230-237. doi: 10.1080/00365521.2016.1249403. Epub 2016 Nov 3.

PMID:
27806647
6.

Elimination of Cigarette Smoke-derived Acetaldehyde in Saliva by Slow-release L-Cysteine Lozenge Is a Potential New Method to Assist Smoking Cessation. A Randomised, Double-blind, Placebo-controlled Intervention.

Syrjänen K, Salminen J, Aresvuo U, Hendolin P, Paloheimo L, Eklund C, Salaspuro M, Suovaniemi O.

Anticancer Res. 2016 May;36(5):2297-306.

PMID:
27127136
7.

ALDH2 Deficiency Promotes Ethanol-Induced Gut Barrier Dysfunction and Fatty Liver in Mice.

Chaudhry KK, Samak G, Shukla PK, Mir H, Gangwar R, Manda B, Isse T, Kawamoto T, Salaspuro M, Kaihovaara P, Dietrich P, Dragatsis I, Nagy LE, Rao RK.

Alcohol Clin Exp Res. 2015 Aug;39(8):1465-75. doi: 10.1111/acer.12777. Epub 2015 Jul 14.

8.

Site-specific acetaldehyde production and microbial colonization in relation to oral squamous cell carcinoma and oral lichenoid disease.

Marttila E, Uittamo J, Rusanen P, Lindqvist C, Salaspuro M, Rautemaa R.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Jun;119(6):697-9. doi: 10.1016/j.oooo.2015.01.019. Epub 2015 Mar 5. No abstract available.

PMID:
25956220
9.

Effects of ALDH2 genotype, PPI treatment and L-cysteine on carcinogenic acetaldehyde in gastric juice and saliva after intragastric alcohol administration.

Maejima R, Iijima K, Kaihovaara P, Hatta W, Koike T, Imatani A, Shimosegawa T, Salaspuro M.

PLoS One. 2015 Apr 1;10(4):e0120397. doi: 10.1371/journal.pone.0120397. eCollection 2015.

10.

ALDH2 genotype has no effect on salivary acetaldehyde without the presence of ethanol in the systemic circulation.

Helminen A, Väkeväinen S, Salaspuro M.

PLoS One. 2013 Sep 13;8(9):e74418. doi: 10.1371/journal.pone.0074418. eCollection 2013.

11.

Acetaldehyde production and microbial colonization in oral squamous cell carcinoma and oral lichenoid disease.

Marttila E, Uittamo J, Rusanen P, Lindqvist C, Salaspuro M, Rautemaa R.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Jul;116(1):61-8. doi: 10.1016/j.oooo.2013.02.009. Epub 2013 Apr 23.

PMID:
23619349
12.

Fermentative 2-carbon metabolism produces carcinogenic levels of acetaldehyde in Candida albicans.

Marttila E, Bowyer P, Sanglard D, Uittamo J, Kaihovaara P, Salaspuro M, Richardson M, Rautemaa R.

Mol Oral Microbiol. 2013 Aug;28(4):281-91. doi: 10.1111/omi.12024. Epub 2013 Feb 28.

PMID:
23445445
13.

Alcohol and acetaldehyde in African fermented milk mursik--a possible etiologic factor for high incidence of esophageal cancer in western Kenya.

Nieminen MT, Novak-Frazer L, Collins R, Dawsey SP, Dawsey SM, Abnet CC, White RE, Freedman ND, Mwachiro M, Bowyer P, Salaspuro M, Rautemaa R.

Cancer Epidemiol Biomarkers Prev. 2013 Jan;22(1):69-75. doi: 10.1158/1055-9965.EPI-12-0908. Epub 2012 Nov 15.

14.

Interactions of alcohol and tobacco in gastrointestinal cancer.

Salaspuro M.

J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2:135-9. doi: 10.1111/j.1440-1746.2012.07017.x. Review. Erratum in: J Gastroenterol Hepatol. 2013 Jul;28(7):1252. Mikko, Salaspuro [corrected to Salaspuro, Mikko].

PMID:
22320931
15.

Rationale in diagnosis and screening of atrophic gastritis with stomach-specific plasma biomarkers.

Agréus L, Kuipers EJ, Kupcinskas L, Malfertheiner P, Di Mario F, Leja M, Mahachai V, Yaron N, van Oijen M, Perez Perez G, Rugge M, Ronkainen J, Salaspuro M, Sipponen P, Sugano K, Sung J.

Scand J Gastroenterol. 2012 Feb;47(2):136-47. doi: 10.3109/00365521.2011.645501. Review. Erratum in: Scand J Gastroenterol. 2012 Dec;47(12):1525.

16.

The unsuitability of split-thickness oral buccal mucosa tissue constructs to judge about the safety of ethanol-containing mouthrinses in vitro.

Lachenmeier DW, Salaspuro M.

Food Chem Toxicol. 2012 May;50(5):1811-2; author reply 1813-4. doi: 10.1016/j.fct.2011.11.025. Epub 2011 Nov 26. No abstract available.

PMID:
22138250
17.

Acetaldehyde level in spirits from central European countries.

Boffetta P, Kaihovaara P, Rudnai P, Znaor A, Lissowska J, Swiatkowska B, Mates D, Pandics T, Salaspuro M.

Eur J Cancer Prev. 2011 Nov;20(6):526-9. doi: 10.1097/CEJ.0b013e328348fbe4.

PMID:
21811156
18.

A single sip of a strong alcoholic beverage causes exposure to carcinogenic concentrations of acetaldehyde in the oral cavity.

Linderborg K, Salaspuro M, Väkeväinen S.

Food Chem Toxicol. 2011 Sep;49(9):2103-6. doi: 10.1016/j.fct.2011.05.024. Epub 2011 May 27.

PMID:
21641957
19.

Acetaldehyde and gastric cancer.

Salaspuro M.

J Dig Dis. 2011 Apr;12(2):51-9. doi: 10.1111/j.1751-2980.2011.00480.x. Review.

PMID:
21401890
20.

Xylitol inhibits carcinogenic acetaldehyde production by Candida species.

Uittamo J, Nieminen MT, Kaihovaara P, Bowyer P, Salaspuro M, Rautemaa R.

Int J Cancer. 2011 Oct 15;129(8):2038-41. doi: 10.1002/ijc.25844. Epub 2011 Apr 1.

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