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Items: 1 to 20 of 41


Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice.

Leon S, Velasco I, Vázquez MJ, Barroso A, Beiroa D, Heras V, Ruiz-Pino F, Manfredi-Lozano M, Romero-Ruiz A, Sanchez-Garrido MA, Dieguez C, Pinilla L, Roa J, Nogueiras R, Tena-Sempere M.

Metabolism. 2018 Jul 31. pii: S0026-0495(18)30167-7. doi: 10.1016/j.metabol.2018.07.003. [Epub ahead of print]


Neonatal Overnutrition Increases Testicular Size and Expression of Luteinizing Hormone β-Subunit in Peripubertal Male Rats.

Argente-Arizón P, Castro-González D, Díaz F, Fernández-Gómez MJ, Sánchez-Garrido MA, Tena-Sempere M, Argente J, Chowen JA.

Front Endocrinol (Lausanne). 2018 Apr 13;9:168. doi: 10.3389/fendo.2018.00168. eCollection 2018.


Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways.

Sanchez-Garrido MA, Ruiz-Pino F, Velasco I, Barroso A, Fernandois D, Heras V, Manfredi-Lozano M, Vazquez MJ, Castellano JM, Roa J, Pinilla L, Tena-Sempere M.

Endocrinology. 2018 Feb 1;159(2):1005-1018. doi: 10.1210/en.2017-00705.


GLP-1/glucagon receptor co-agonism for treatment of obesity.

Sánchez-Garrido MA, Brandt SJ, Clemmensen C, Müller TD, DiMarchi RD, Tschöp MH.

Diabetologia. 2017 Oct;60(10):1851-1861. doi: 10.1007/s00125-017-4354-8. Epub 2017 Jul 21. Review.


Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.

Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Müller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sánchez-Garrido MA, Liu P, Tuckermann J, Malehmir M, Healy ME, Weber A, Heikenwalder M, Jastroch M, Kleinert M, Jall S, Brandt S, Flamant F, Schramm KW, Biebermann H, Döring Y, Weber C, Habegger KM, Keuper M, Gelfanov V, Liu F, Köhrle J, Rozman J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Hofmann SM, Yang B, Tschöp MH, DiMarchi R, Müller TD.

Cell. 2016 Oct 20;167(3):843-857.e14. doi: 10.1016/j.cell.2016.09.014. Epub 2016 Oct 6.


Neonatal Androgen Exposure Causes Persistent Gut Microbiota Dysbiosis Related to Metabolic Disease in Adult Female Rats.

Moreno-Indias I, Sánchez-Alcoholado L, Sánchez-Garrido MÁ, Martín-Núñez GM, Pérez-Jiménez F, Tena-Sempere M, Tinahones FJ, Queipo-Ortuño MI.

Endocrinology. 2016 Dec;157(12):4888-4898. Epub 2016 Oct 4.


Fibroblast activation protein (FAP) as a novel metabolic target.

Sánchez-Garrido MA, Habegger KM, Clemmensen C, Holleman C, Müller TD, Perez-Tilve D, Li P, Agrawal AS, Finan B, Drucker DJ, Tschöp MH, DiMarchi RD, Kharitonenkov A.

Mol Metab. 2016 Jul 16;5(10):1015-1024. doi: 10.1016/j.molmet.2016.07.003. eCollection 2016 Oct.


Defining a novel leptin-melanocortin-kisspeptin pathway involved in the metabolic control of puberty.

Manfredi-Lozano M, Roa J, Ruiz-Pino F, Piet R, Garcia-Galiano D, Pineda R, Zamora A, Leon S, Sanchez-Garrido MA, Romero-Ruiz A, Dieguez C, Vazquez MJ, Herbison AE, Pinilla L, Tena-Sempere M.

Mol Metab. 2016 Aug 11;5(10):844-857. doi: 10.1016/j.molmet.2016.08.003. eCollection 2016 Oct.


Age and sex dependent effects of early overnutrition on metabolic parameters and the role of neonatal androgens.

Argente-Arizón P, Ros P, Díaz F, Fuente-Martin E, Castro-González D, Sánchez-Garrido MÁ, Barrios V, Tena-Sempere M, Argente J, Chowen JA.

Biol Sex Differ. 2016 May 18;7:26. doi: 10.1186/s13293-016-0079-5. eCollection 2016.


Renaissance of leptin for obesity therapy.

Quarta C, Sánchez-Garrido MA, Tschöp MH, Clemmensen C.

Diabetologia. 2016 May;59(5):920-7. doi: 10.1007/s00125-016-3906-7. Epub 2016 Mar 16. Review.


Metabolic and Gonadotropic Impact of Sequential Obesogenic Insults in the Female: Influence of the Loss of Ovarian Secretion.

Sánchez-Garrido MA, Ruiz-Pino F, Manfredi-Lozano M, Leon S, Heras V, Castellano JM, Castaño JP, Luque RM, Vázquez MJ, Roa J, Romero-Ruiz A, Diéguez C, Pinilla L, Tena-Sempere M.

Endocrinology. 2015 Aug;156(8):2984-98. doi: 10.1210/en.2014-1951. Epub 2015 May 18.


Increased prepubertal body weight enhances leptin sensitivity in proopiomelanocortin and neuropeptide y neurons before puberty onset in female rats.

Castro-González D, Fuente-Martín E, Sánchez-Garrido MA, Argente-Arizón P, Tena-Sempere M, Barrios V, Chowen JA, Argente J.

Endocrinology. 2015 Apr;156(4):1272-82. doi: 10.1210/en.2014-1759. Epub 2015 Jan 9.


Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats.

Ruiz-Pino F, Garcia-Galiano D, Manfredi-Lozano M, Leon S, Sánchez-Garrido MA, Roa J, Pinilla L, Navarro VM, Tena-Sempere M.

Endocrinology. 2015 Feb;156(2):576-88. doi: 10.1210/en.2014-1026. Epub 2014 Dec 9.


Neonatal events, such as androgenization and postnatal overfeeding, modify the response to ghrelin.

Novelle MG, Vázquez MJ, Martinello KD, Sanchez-Garrido MA, Tena-Sempere M, Diéguez C.

Sci Rep. 2014 May 6;4:4855. doi: 10.1038/srep04855.


Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms.

Sánchez-Garrido MA, Ruiz-Pino F, Manfredi-Lozano M, Leon S, Garcia-Galiano D, Castaño JP, Luque RM, Romero-Ruiz A, Castellano JM, Diéguez C, Pinilla L, Tena-Sempere M.

Endocrinology. 2014 Mar;155(3):1067-79. doi: 10.1210/en.2013-1584. Epub 2014 Jan 1.


Metabolic control of puberty: roles of leptin and kisspeptins.

Sanchez-Garrido MA, Tena-Sempere M.

Horm Behav. 2013 Jul;64(2):187-94. doi: 10.1016/j.yhbeh.2013.01.014. Review.


Metabolic programming of puberty: sexually dimorphic responses to early nutritional challenges.

Sánchez-Garrido MA, Castellano JM, Ruiz-Pino F, Garcia-Galiano D, Manfredi-Lozano M, Leon S, Romero-Ruiz A, Diéguez C, Pinilla L, Tena-Sempere M.

Endocrinology. 2013 Sep;154(9):3387-400. doi: 10.1210/en.2012-2157. Epub 2013 Jun 10.


Characterization of the reproductive effects of the Vgf-derived peptide TLQP-21 in female rats: in vivo and in vitro studies.

Aguilar E, Pineda R, Gaytán F, Sánchez-Garrido MA, Romero M, Romero-Ruiz A, Ruiz-Pino F, Tena-Sempere M, Pinilla L.

Neuroendocrinology. 2013;98(1):38-50. doi: 10.1159/000350323. Epub 2013 Jun 28.


Changes in hypothalamic expression of the Lin28/let-7 system and related microRNAs during postnatal maturation and after experimental manipulations of puberty.

Sangiao-Alvarellos S, Manfredi-Lozano M, Ruiz-Pino F, Navarro VM, Sánchez-Garrido MA, Leon S, Dieguez C, Cordido F, Matagne V, Dissen GA, Ojeda SR, Pinilla L, Tena-Sempere M.

Endocrinology. 2013 Feb;154(2):942-55. doi: 10.1210/en.2012-2006. Epub 2013 Jan 4.


Leptin regulates glutamate and glucose transporters in hypothalamic astrocytes.

Fuente-Martín E, García-Cáceres C, Granado M, de Ceballos ML, Sánchez-Garrido MÁ, Sarman B, Liu ZW, Dietrich MO, Tena-Sempere M, Argente-Arizón P, Díaz F, Argente J, Horvath TL, Chowen JA.

J Clin Invest. 2012 Nov;122(11):3900-13. doi: 10.1172/JCI64102. Epub 2012 Oct 15.

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