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Items: 1 to 20 of 33


Pioneering of Enhancer Landscapes during Pluripotent State Transitions.

Rada-Iglesias A.

Cell Stem Cell. 2018 Aug 2;23(2):149-151. doi: 10.1016/j.stem.2018.07.012.


Forces driving the three-dimensional folding of eukaryotic genomes.

Rada-Iglesias A, Grosveld FG, Papantonis A.

Mol Syst Biol. 2018 Jun 1;14(6):e8214. doi: 10.15252/msb.20188214. Review.


Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation.

Fueyo R, Iacobucci S, Pappa S, Estarás C, Lois S, Vicioso-Mantis M, Navarro C, Cruz-Molina S, Reyes JC, Rada-Iglesias Á, de la Cruz X, Martínez-Balbás MA.

Nucleic Acids Res. 2018 Apr 20;46(7):3351-3365. doi: 10.1093/nar/gky093.


Is H3K4me1 at enhancers correlative or causative?

Rada-Iglesias A.

Nat Genet. 2018 Jan;50(1):4-5. doi: 10.1038/s41588-017-0018-3. No abstract available.


Ready, Set…Poised!: Polycomb target genes are bound by poised RNA polymerase II throughout differentiation.

Rada-Iglesias A.

Mol Syst Biol. 2017 Oct 23;13(10):950. doi: 10.15252/msb.20177968. No abstract available.


Chromatin Immunoprecipitation (ChIP) Protocol for Low-abundance Embryonic Samples.

Rehimi R, Bartusel M, Solinas F, Altmüller J, Rada-Iglesias A.

J Vis Exp. 2017 Aug 29;(126). doi: 10.3791/56186.


PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation.

Cruz-Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, van Ijcken WFJ, Grosveld F, Frommolt P, Bazzi H, Rada-Iglesias A.

Cell Stem Cell. 2017 May 4;20(5):689-705.e9. doi: 10.1016/j.stem.2017.02.004. Epub 2017 Mar 9.


Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.

Ludwig KU, Böhmer AC, Bowes J, Nikolic M, Ishorst N, Wyatt N, Hammond NL, Gölz L, Thieme F, Barth S, Schuenke H, Klamt J, Spielmann M, Aldhorae K, Rojas-Martinez A, Nöthen MM, Rada-Iglesias A, Dixon MJ, Knapp M, Mangold E.

Hum Mol Genet. 2017 Feb 15;26(4):829-842. doi: 10.1093/hmg/ddx012.


GARLIC: a bioinformatic toolkit for aetiologically connecting diseases and cell type-specific regulatory maps.

Nikolic M, Papantonis A, Rada-Iglesias A.

Hum Mol Genet. 2017 Feb 15;26(4):742-752. doi: 10.1093/hmg/ddw423.


Epigenomics-Based Identification of Major Cell Identity Regulators within Heterogeneous Cell Populations.

Rehimi R, Nikolic M, Cruz-Molina S, Tebartz C, Frommolt P, Mahabir E, Clément-Ziza M, Rada-Iglesias A.

Cell Rep. 2016 Dec 13;17(11):3062-3076. doi: 10.1016/j.celrep.2016.11.046.


Foxd3 Promotes Exit from Naive Pluripotency through Enhancer Decommissioning and Inhibits Germline Specification.

Respuela P, Nikolić M, Tan M, Frommolt P, Zhao Y, Wysocka J, Rada-Iglesias A.

Cell Stem Cell. 2016 Jan 7;18(1):118-33. doi: 10.1016/j.stem.2015.09.010.


Genetic variation within transcriptional regulatory elements and its implications for human disease.

Rada-Iglesias A.

Biol Chem. 2014 Dec;395(12):1453-60. doi: 10.1515/hsz-2014-0109. Review.


Human genetic variation within neural crest enhancers: molecular and phenotypic implications.

Rada-Iglesias A, Prescott SL, Wysocka J.

Philos Trans R Soc Lond B Biol Sci. 2013 May 6;368(1620):20120360. doi: 10.1098/rstb.2012.0360. Print 2013. Review.


Pioneering barren land: mitotic bookmarking by transcription factors.

Rada-Iglesias A.

Dev Cell. 2013 Feb 25;24(4):342-4. doi: 10.1016/j.devcel.2013.02.005.


Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest.

Rada-Iglesias A, Bajpai R, Prescott S, Brugmann SA, Swigut T, Wysocka J.

Cell Stem Cell. 2012 Nov 2;11(5):633-48. doi: 10.1016/j.stem.2012.07.006. Epub 2012 Sep 13.


The homeodomain-leucine zipper (HD-Zip) class I transcription factors ATHB7 and ATHB12 modulate abscisic acid signalling by regulating protein phosphatase 2C and abscisic acid receptor gene activities.

Valdés AE, Overnäs E, Johansson H, Rada-Iglesias A, Engström P.

Plant Mol Biol. 2012 Nov;80(4-5):405-18. doi: 10.1007/s11103-012-9956-4. Epub 2012 Sep 12.


Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates.

Ma Z, Swigut T, Valouev A, Rada-Iglesias A, Wysocka J.

Nat Struct Mol Biol. 2011 Feb;18(2):120-7. doi: 10.1038/nsmb.2000. Epub 2010 Dec 23.


A unique chromatin signature uncovers early developmental enhancers in humans.

Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J.

Nature. 2011 Feb 10;470(7333):279-83. doi: 10.1038/nature09692. Epub 2010 Dec 15.


Integrative epigenomic and genomic analysis of malignant pheochromocytoma.

Sandgren J, Andersson R, Rada-Iglesias A, Enroth S, Akerstrom G, Dumanski JP, Komorowski J, Westin G, Wadelius C.

Exp Mol Med. 2010 Jul 31;42(7):484-502.

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