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Items: 1 to 20 of 50

1.

CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1.

Huynh KW, Jiang J, Abuladze N, Tsirulnikov K, Kao L, Shao X, Newman D, Azimov R, Pushkin A, Zhou ZH, Kurtz I.

Nat Commun. 2018 Mar 2;9(1):900. doi: 10.1038/s41467-018-03271-3.

2.

Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma.

Tsirulnikov K, Duarte S, Ray A, Datta N, Zarrinpar A, Hwang L, Faull K, Pushkin A, Kurtz I.

J Cancer. 2018 Jan 1;9(1):1-12. doi: 10.7150/jca.21747. eCollection 2018.

3.

Single particle electron microscopy analysis of the bovine anion exchanger 1 reveals a flexible linker connecting the cytoplasmic and membrane domains.

Jiang J, Magilnick N, Tsirulnikov K, Abuladze N, Atanasov I, Ge P, Narla M, Pushkin A, Zhou ZH, Kurtz I.

PLoS One. 2013;8(2):e55408. doi: 10.1371/journal.pone.0055408. Epub 2013 Feb 5.

4.

Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein.

Tsirulnikov K, Abuladze N, Vahi R, Hasnain H, Phillips M, Ryan CM, Atanasov I, Faull KF, Kurtz I, Pushkin A.

FEBS Lett. 2012 Nov 2;586(21):3799-804. doi: 10.1016/j.febslet.2012.09.015. Epub 2012 Sep 22.

5.

Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal.

Tsirulnikov K, Abuladze N, Bragin A, Faull K, Cascio D, Damoiseaux R, Schibler MJ, Pushkin A.

Toxicol Appl Pharmacol. 2012 Sep 15;263(3):303-14. doi: 10.1016/j.taap.2012.07.002. Epub 2012 Jul 20.

6.

Structures of aminoacylase 3 in complex with acetylated substrates.

Hsieh JM, Tsirulnikov K, Sawaya MR, Magilnick N, Abuladze N, Kurtz I, Abramson J, Pushkin A.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):17962-7. doi: 10.1073/pnas.1006687107. Epub 2010 Oct 4.

7.

Structural and functional characterization of the C-terminal transmembrane region of NBCe1-A.

Zhu Q, Kao L, Azimov R, Abuladze N, Newman D, Pushkin A, Liu W, Chang C, Kurtz I.

J Biol Chem. 2010 Nov 26;285(48):37178-87. doi: 10.1074/jbc.M110.169201. Epub 2010 Sep 13.

8.

Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis.

Zhu Q, Kao L, Azimov R, Newman D, Liu W, Pushkin A, Abuladze N, Kurtz I.

J Biol Chem. 2010 Apr 30;285(18):13416-26. doi: 10.1074/jbc.M109.093286. Epub 2010 Mar 2.

9.

Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2).

Tsirulnikov K, Abuladze N, Koag MC, Newman D, Scholz K, Bondar G, Zhu Q, Avliyakulov NK, Dekant W, Faull K, Kurtz I, Pushkin A.

Toxicol Appl Pharmacol. 2010 Apr 15;244(2):218-25. doi: 10.1016/j.taap.2009.12.035. Epub 2010 Jan 6.

10.

Slc4a11 gene disruption in mice: cellular targets of sensorineuronal abnormalities.

Lopez IA, Rosenblatt MI, Kim C, Galbraith GC, Jones SM, Kao L, Newman D, Liu W, Yeh S, Pushkin A, Abuladze N, Kurtz I.

J Biol Chem. 2009 Sep 25;284(39):26882-96. doi: 10.1074/jbc.M109.008102. Epub 2009 Jul 8.

11.

Mouse aminoacylase 3: a metalloenzyme activated by cobalt and nickel.

Tsirulnikov K, Abuladze N, Newman D, Ryazantsev S, Wolak T, Magilnick N, Koag MC, Kurtz I, Pushkin A.

Biochim Biophys Acta. 2009 Jul;1794(7):1049-57. doi: 10.1016/j.bbapap.2009.03.022. Epub 2009 Apr 9.

12.

NBCe1-A Transmembrane Segment 1 Lines the Ion Translocation Pathway.

Zhu Q, Azimov R, Kao L, Newman D, Liu W, Abuladze N, Pushkin A, Kurtz I.

J Biol Chem. 2009 Mar 27;284(13):8918-29. doi: 10.1074/jbc.M806674200. Epub 2009 Jan 21.

13.

Oligomeric structure and minimal functional unit of the electrogenic sodium bicarbonate cotransporter NBCe1-A.

Kao L, Sassani P, Azimov R, Pushkin A, Abuladze N, Peti-Peterdi J, Liu W, Newman D, Kurtz I.

J Biol Chem. 2008 Sep 26;283(39):26782-94. doi: 10.1074/jbc.M804006200. Epub 2008 Jul 25.

14.

G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis.

Azimov R, Abuladze N, Sassani P, Newman D, Kao L, Liu W, Orozco N, Ruchala P, Pushkin A, Kurtz I.

Am J Physiol Renal Physiol. 2008 Sep;295(3):F633-41. doi: 10.1152/ajprenal.00015.2008. Epub 2008 Jul 9.

15.

Role of NBCe1 and AE2 in secretory ameloblasts.

Paine ML, Snead ML, Wang HJ, Abuladze N, Pushkin A, Liu W, Kao LY, Wall SM, Kim YH, Kurtz I.

J Dent Res. 2008 Apr;87(4):391-5.

16.

Measurement of aminoacylases.

Pushkin A, Kurtz I.

Curr Protoc Toxicol. 2008 Feb;Chapter 6:Unit6.14. doi: 10.1002/0471140856.tx0614s35.

PMID:
23045009
17.

Structural characterization of dimeric murine aminoacylase III.

Ryazantsev S, Abuladze N, Newman D, Bondar G, Kurtz I, Pushkin A.

FEBS Lett. 2007 May 1;581(9):1898-902. Epub 2007 Apr 9.

18.

Specificity of aminoacylase III-mediated deacetylation of mercapturic acids.

Newman D, Abuladze N, Scholz K, Dekant W, Tsuprun V, Ryazantsev S, Bondar G, Sassani P, Kurtz I, Pushkin A.

Drug Metab Dispos. 2007 Jan;35(1):43-50. Epub 2006 Sep 29.

19.
20.

Critical amino acid residues involved in the electrogenic sodium-bicarbonate cotransporter kNBC1-mediated transport.

Abuladze N, Azimov R, Newman D, Sassani P, Liu W, Tatishchev S, Pushkin A, Kurtz I.

J Physiol. 2005 Jun 15;565(Pt 3):717-30. Epub 2005 Apr 7.

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