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Items: 1 to 20 of 103


Staphylococcus aureus small colony variants impair host immunity by activating host cell glycolysis and inducing necroptosis.

Wong Fok Lung T, Monk IR, Acker KP, Mu A, Wang N, Riquelme SA, Pires S, Noguera LP, Dach F, Gabryszewski SJ, Howden BP, Prince A.

Nat Microbiol. 2019 Nov 4. doi: 10.1038/s41564-019-0597-0. [Epub ahead of print]


Strains of Staphylococcus aureus that Colonize and Infect Skin Harbor Mutations in Metabolic Genes.

Acker KP, Wong Fok Lung T, West E, Craft J, Narechania A, Smith H, O'Brien K, Moustafa AM, Lauren C, Planet PJ, Prince A.

iScience. 2019 Sep 27;19:281-290. doi: 10.1016/j.isci.2019.07.037. Epub 2019 Jul 26.


CFTR-PTEN-dependent mitochondrial metabolic dysfunction promotes Pseudomonas aeruginosa airway infection.

Riquelme SA, Lozano C, Moustafa AM, Liimatta K, Tomlinson KL, Britto C, Khanal S, Gill SK, Narechania A, Azcona-Gutiérrez JM, DiMango E, Saénz Y, Planet P, Prince A.

Sci Transl Med. 2019 Jul 3;11(499). pii: eaav4634. doi: 10.1126/scitranslmed.aav4634.


Interleukin-10 Produced by Myeloid-Derived Suppressor Cells Provides Protection to Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 258 by Enhancing Its Clearance in the Airways.

Peñaloza HF, Noguera LP, Ahn D, Vallejos OP, Castellanos RM, Vazquez Y, Salazar-Echegarai FJ, González L, Suazo I, Pardo-Roa C, Salazar GA, Prince A, Bueno SM.

Infect Immun. 2019 Apr 23;87(5). pii: e00665-18. doi: 10.1128/IAI.00665-18. Print 2019 Mar.


Metabolic Adaptation in Methicillin-Resistant Staphylococcus aureus Pneumonia.

Gabryszewski SJ, Wong Fok Lung T, Annavajhala MK, Tomlinson KL, Riquelme SA, Khan IN, Noguera LP, Wickersham M, Zhao A, Mulenos AM, Peaper D, Koff JL, Uhlemann AC, Prince A.

Am J Respir Cell Mol Biol. 2019 Aug;61(2):185-197. doi: 10.1165/rcmb.2018-0389OC.


The Effects of IFN-λ on Epithelial Barrier Function Contribute to Klebsiella pneumoniae ST258 Pneumonia.

Ahn D, Wickersham M, Riquelme S, Prince A.

Am J Respir Cell Mol Biol. 2019 Feb;60(2):158-166. doi: 10.1165/rcmb.2018-0021OC.


Omissions from a National Institute of Health (NIH) biosketch.

Prince A.

PLoS Pathog. 2018 May 10;14(5):e1006896. doi: 10.1371/journal.ppat.1006896. eCollection 2018 May. No abstract available.


Future Research Directions in Pneumonia. NHLBI Working Group Report.

Dela Cruz CS, Wunderink RG, Christiani DC, Cormier SA, Crothers K, Doerschuk CM, Evans SE, Goldstein DR, Khatri P, Kobzik L, Kolls JK, Levy BD, Metersky ML, Niederman MS, Nusrat R, Orihuela CJ, Peyrani P, Prince AS, Ramírez JA, Ridge KM, Sethi S, Suratt BT, Sznajder JI, Tsalik EL, Walkey AJ, Yende S, Aggarwal NR, Caler EV, Mizgerd JP.

Am J Respir Crit Care Med. 2018 Jul 15;198(2):256-263. doi: 10.1164/rccm.201801-0139WS.


Disruption of staphylococcal aggregation protects against lethal lung injury.

Hook JL, Islam MN, Parker D, Prince AS, Bhattacharya S, Bhattacharya J.

J Clin Invest. 2018 Mar 1;128(3):1074-1086. doi: 10.1172/JCI95823. Epub 2018 Feb 12.


Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity.

Riquelme SA, Hopkins BD, Wolfe AL, DiMango E, Kitur K, Parsons R, Prince A.

Immunity. 2017 Dec 19;47(6):1169-1181.e7. doi: 10.1016/j.immuni.2017.11.010. Epub 2017 Dec 12.


Metabolic Stress Drives Keratinocyte Defenses against Staphylococcus aureus Infection.

Wickersham M, Wachtel S, Wong Fok Lung T, Soong G, Jacquet R, Richardson A, Parker D, Prince A.

Cell Rep. 2017 Mar 14;18(11):2742-2751. doi: 10.1016/j.celrep.2017.02.055.


Participation of Host Determinants in the Pathogenesis of Pneumonia.

Prince A.

J Innate Immun. 2017;9(3):229-231. doi: 10.1159/000460276. Epub 2017 Mar 4. No abstract available.


Participation of Necroptosis in the Host Response to Acute Bacterial Pneumonia.

Ahn D, Prince A.

J Innate Immun. 2017;9(3):262-270. doi: 10.1159/000455100. Epub 2017 Jan 27. Review.


Acquired resistance to innate immune clearance promotes Klebsiella pneumoniae ST258 pulmonary infection.

Ahn D, Peñaloza H, Wang Z, Wickersham M, Parker D, Patel P, Koller A, Chen EI, Bueno SM, Uhlemann AC, Prince A.

JCI Insight. 2016 Oct 20;1(17):e89704. doi: 10.1172/jci.insight.89704.


Immunoregulatory effects of necroptosis in bacterial infections.

Parker D, Prince A.

Cytokine. 2016 Dec;88:274-275. doi: 10.1016/j.cyto.2016.09.024. Epub 2016 Oct 3. No abstract available.


Humanized Mice Exhibit Increased Susceptibility to Staphylococcus aureus Pneumonia.

Prince A, Wang H, Kitur K, Parker D.

J Infect Dis. 2017 May 1;215(9):1386-1395. doi: 10.1093/infdis/jiw425.


Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.

Kitur K, Wachtel S, Brown A, Wickersham M, Paulino F, Peñaloza HF, Soong G, Bueno S, Parker D, Prince A.

Cell Rep. 2016 Aug 23;16(8):2219-2230. doi: 10.1016/j.celrep.2016.07.039. Epub 2016 Aug 11.


A new approach to toxin neutralization in Staphylococcus aureus therapy.

Parker D, Prince A.

EMBO Rep. 2016 Mar;17(3):284-5. doi: 10.15252/embr.201642015. Epub 2016 Feb 8. No abstract available.


Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection.

Planet PJ, Parker D, Cohen TS, Smith H, Leon JD, Ryan C, Hammer TJ, Fierer N, Chen EI, Prince AS.

MBio. 2016 Feb 9;7(1):e01939-15. doi: 10.1128/mBio.01939-15.

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