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Items: 1 to 20 of 131

1.

Psychopharmacological effects and safety of styryl-2-pyrones and dihydrostyryl-2-pyrones-rich fraction from Polygala sabulosa: absence of withdrawal syndrome and tolerance to anxiolytic-like and anticonvulsant effects.

Duarte FS, Duzzioni M, Prim RL, Cardozo AM, Dos Santos CR, da Silva MG, Shiozawa MBC, Mendes BG, Tizziani T, Brighente IMC, Pizzolatti MG, de Lima TCM.

J Pharm Pharmacol. 2018 Sep;70(9):1272-1286. doi: 10.1111/jphp.12960. Epub 2018 Jun 28.

2.

Fern-9(11)-ene-2α,3β-diol Action on Insulin Secretion under Hyperglycemic Conditions.

Castro AJG, Cazarolli LH, da Luz G, Altenhofen D, da Silva HB, de Carvalho FK, Pizzolatti MG, Silva FRMB.

Biochemistry. 2018 Jul 3;57(26):3894-3902. doi: 10.1021/acs.biochem.8b00302. Epub 2018 Jun 11.

PMID:
29792023
3.

The potent insulin secretagogue effect of betulinic acid is mediated by potassium and chloride channels.

Gomes Castro AJ, Cazarolli LH, Bretanha LC, Sulis PM, Rey Padilla DP, Aragón Novoa DM, Dambrós BF, Pizzolatti MG, Mena Barreto Silva FR.

Arch Biochem Biophys. 2018 Jun 15;648:20-26. doi: 10.1016/j.abb.2018.04.015. Epub 2018 Apr 25.

PMID:
29704483
4.

Synthesis of lupeol derivatives and their antileishmanial and antitrypanosomal activities.

Machado VR, Sandjo LP, Pinheiro GL, Moraes MH, Steindel M, Pizzolatti MG, Biavatti MW.

Nat Prod Res. 2018 Feb;32(3):275-281. doi: 10.1080/14786419.2017.1353982. Epub 2017 Jul 17.

PMID:
28715940
5.

Effects of two 6-quinolinyl chalcones on the integrity of plasma membrane of Paracoccidioides brasiliensis.

de Sá NP, Cisalpino PS, Tavares LC, Espíndola L, Borelli BM, Barbeira PJ, Cardoso Perdigão GM, Souza-Fagundes EM, Rosa CA, Pizzolatti MG, Johann S.

J Antibiot (Tokyo). 2017 Mar;70(3):277-284. doi: 10.1038/ja.2016.156. Epub 2017 Jan 11.

PMID:
28074055
6.

Bis-Pyrano Prenyl Isoflavone Improves Glucose Homeostasis by Inhibiting Dipeptidyl Peptidase-4 in Hyperglycemic Rats.

Altenhofen D, da Luz G, Frederico MJ, Venzke D, Brich M, Vigil S, Fröde TS, Linares CE, Pizzolatti MG, Silva FR.

J Cell Biochem. 2017 Jan;118(1):92-103. doi: 10.1002/jcb.25614. Epub 2016 Jun 13.

PMID:
27238050
7.

Triterpene derivative: A potential signaling pathway for the fern-9(11)-ene-2α,3β-diol on insulin secretion in pancreatic islet.

da Luz G, Frederico MJ, Castro AJ, Moraes AL, de Carvalho FK, Espíndola L, Schmidt ÉC, Bouzon ZL, Pizzolatti MG, Silva FR.

Life Sci. 2016 Jun 1;154:58-65. doi: 10.1016/j.lfs.2016.04.027. Epub 2016 Apr 22.

PMID:
27108785
8.

Antinociceptive effect of hydroalcoholic extract and isoflavone isolated from Polygala molluginifolia in mice: evidence for the involvement of opioid receptors and TRPV1 and TRPA1 channels.

Nucci-Martins C, Nascimento LF, Venzke D, Brethanha LC, Sako AV, Oliveira AS, Brighente IM, Micke GA, Pizzolatti MG, Santos AR.

Phytomedicine. 2016 May 15;23(5):429-40. doi: 10.1016/j.phymed.2016.02.002. Epub 2016 Mar 2.

PMID:
27064002
9.

Chemical constituents of Eugenia catharinae and their antioxidant activity.

Moresco HH, Colla G, Cavalcante ID, Queiroz GS, Pizzolatti MG, Brighente IMC.

Nat Prod Res. 2016 Nov;30(22):2624-2628. doi: 10.1080/14786419.2015.1131981. Epub 2016 Jan 13.

PMID:
26758384
10.

7-prenyloxi-6-methoxycoumarin from Polygala sabulosa A.W. Bennett Regulates p38 MAPK and NF-kB Pathways Inhibiting the Inflammation Induced by Carrageenan in the Mouse Model of Pleurisy.

Dos Santos Nascimento MV, Arruda-Silva F, Luz AB, Venzke D, Queiroz GS, Mendes BG, Fernandes-Ribeiro ER, Fröde TS, Pizzolatti MG, Dalmarco EM.

Inflamm Allergy Drug Targets. 2015;14(1):37-46.

PMID:
26434700
11.

Pharmacological evidence favouring the traditional use of the root bark of Condalia buxifolia Reissek in the relief of pain and inflammation in mice.

Simões RR, Coelho IS, Junqueira SC, Maldaner G, Morel AF, Venzke D, Ruani AP, Pizzolatti MG, Zanchet EM, Santos AR.

J Ethnopharmacol. 2015 Dec 4;175:370-7. doi: 10.1016/j.jep.2015.09.028. Epub 2015 Sep 25.

PMID:
26409180
12.

Ameliorative potential of standardized fruit extract of Pterodon pubescens Benth on neuropathic pain in mice: Evidence for the mechanisms of action.

Nucci-Martins C, Martins DF, Nascimento LF, Venzke D, Oliveira AS, Frederico MJ, Silva FR, Brighente IM, Pizzolatti MG, Santos AR.

J Ethnopharmacol. 2015 Dec 4;175:273-86. doi: 10.1016/j.jep.2015.09.005. Epub 2015 Sep 18.

PMID:
26386380
13.

Inhalation of Cedrus atlantica essential oil alleviates pain behavior through activation of descending pain modulation pathways in a mouse model of postoperative pain.

Martins DF, Emer AA, Batisti AP, Donatello N, Carlesso MG, Mazzardo-Martins L, Venzke D, Micke GA, Pizzolatti MG, Piovezan AP, dos Santos AR.

J Ethnopharmacol. 2015 Dec 4;175:30-8. doi: 10.1016/j.jep.2015.08.048. Epub 2015 Sep 4.

14.

Acute effect of 3β-hidroxihop-22(29)ene on insulin secretion is mediated by GLP-1, potassium and calcium channels for the glucose homeostasis.

Castro AJ, Cazarolli LH, de Carvalho FK, da Luz G, Altenhofen D, dos Santos AR, Pizzolatti MG, Silva FR.

J Steroid Biochem Mol Biol. 2015 Jun;150:112-22. doi: 10.1016/j.jsbmb.2015.03.011. Epub 2015 Apr 2.

15.

Modulatory effect of Senecio brasiliensis (Spreng) Less. in a murine model of inflammation induced by carrageenan into the pleural cavity.

de Souza RR, Bretanha LC, Dalmarco EM, Pizzolatti MG, Fröde TS.

J Ethnopharmacol. 2015 Jun 20;168:373-9. doi: 10.1016/j.jep.2015.03.032. Epub 2015 Mar 31.

PMID:
25839117
16.

Antifungal activity of 6-quinolinyl N-oxide chalcones against Paracoccidioides.

de Sá NP, Cisalpino PS, Tavares Lde C, Espíndola L, Pizzolatti MG, Santos PC, de Paula TP, Rosa CA, de Souza Dda G, Santos DA, Johann S.

J Antimicrob Chemother. 2015 Mar;70(3):841-5. doi: 10.1093/jac/dku427. Epub 2014 Oct 31.

PMID:
25362572
17.

The mechanism of action of ursolic acid as insulin secretagogue and insulinomimetic is mediated by cross-talk between calcium and kinases to regulate glucose balance.

Castro AJ, Frederico MJ, Cazarolli LH, Mendes CP, Bretanha LC, Schmidt ÉC, Bouzon ZL, de Medeiros Pinto VA, da Fonte Ramos C, Pizzolatti MG, Silva FR.

Biochim Biophys Acta. 2015 Jan;1850(1):51-61. doi: 10.1016/j.bbagen.2014.10.001. Epub 2014 Oct 13.

18.

Polygala molluginifolia A. St.-Hil. and Moq. prevent inflammation in the mouse pleurisy model by inhibiting NF-κB activation.

Arruda-Silva F, Nascimento MV, Luz AB, Venzke D, Queiroz GS, Fröde TS, Pizzolatti MG, Dalmarco EM.

Int Immunopharmacol. 2014 Apr;19(2):334-41. doi: 10.1016/j.intimp.2014.02.010. Epub 2014 Feb 20.

PMID:
24560858
19.

Neuroprotective effect of the proanthocyanidin-rich fraction in experimental model of spinal cord injury.

Assis LC, Hort MA, de Souza GV, Martini AC, Forner S, Martins DF, Silva JC, Horst H, dos Santos AR, Pizzolatti MG, Rae GA, Koepp J, de Bem AF, do Valle RM.

J Pharm Pharmacol. 2014 May;66(5):694-704. doi: 10.1111/jphp.12177. Epub 2014 Jan 20.

PMID:
24438047
20.

Relationship of chemical structure and anti-inflammatory activity of dihydrocorynantheol and its analogues.

Pozzatti P, Dos Reis GO, Pereira DF, Horst H, Espindola L, Heller M, Micke GA, Pizzolatti MG, Fröde TS.

Pharmacol Rep. 2013;65(5):1263-71.

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