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Items: 1 to 20 of 59

1.

Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells.

Page N, Klimek B, De Roo M, Steinbach K, Soldati H, Lemeille S, Wagner I, Kreutzfeldt M, Di Liberto G, Vincenti I, Lingner T, Salinas G, Brück W, Simons M, Murr R, Kaye J, Zehn D, Pinschewer DD, Merkler D.

Immunity. 2019 Mar 19;50(3):763. doi: 10.1016/j.immuni.2019.02.011. No abstract available.

PMID:
30893589
2.

Residual LCMV antigen in transiently CD4+ T cell-depleted mice induces high levels of virus-specific antibodies but only limited B-cell memory.

Schweier O, Aichele U, Marx AF, Straub T, Verbeek JS, Pinschewer DD, Pircher H.

Eur J Immunol. 2019 Apr;49(4):626-637. doi: 10.1002/eji.201847772. Epub 2019 Feb 4.

PMID:
30636035
3.

Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping.

Di Liberto G, Pantelyushin S, Kreutzfeldt M, Page N, Musardo S, Coras R, Steinbach K, Vincenti I, Klimek B, Lingner T, Salinas G, Lin-Marq N, Staszewski O, Costa Jordão MJ, Wagner I, Egervari K, Mack M, Bellone C, Blümcke I, Prinz M, Pinschewer DD, Merkler D.

Cell. 2018 Oct 4;175(2):458-471.e19. doi: 10.1016/j.cell.2018.07.049. Epub 2018 Aug 30.

PMID:
30173917
4.

Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells.

Page N, Klimek B, De Roo M, Steinbach K, Soldati H, Lemeille S, Wagner I, Kreutzfeldt M, Di Liberto G, Vincenti I, Lingner T, Salinas G, Brück W, Simons M, Murr R, Kaye J, Zehn D, Pinschewer DD, Merkler D.

Immunity. 2018 May 15;48(5):937-950.e8. doi: 10.1016/j.immuni.2018.04.005. Erratum in: Immunity. 2019 Mar 19;50(3):763.

5.

Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.

Khamina K, Lercher A, Caldera M, Schliehe C, Vilagos B, Sahin M, Kosack L, Bhattacharya A, Májek P, Stukalov A, Sacco R, James LC, Pinschewer DD, Bennett KL, Menche J, Bergthaler A.

PLoS Pathog. 2017 Dec 20;13(12):e1006758. doi: 10.1371/journal.ppat.1006758. eCollection 2017 Dec.

6.

Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever.

Remy MM, Sahin M, Flatz L, Regen T, Xu L, Kreutzfeldt M, Fallet B, Doras C, Rieger T, Bestmann L, Hanisch UK, Kaufmann BA, Merkler D, Pinschewer DD.

Cell Host Microbe. 2017 Sep 13;22(3):354-365.e5. doi: 10.1016/j.chom.2017.07.008. Epub 2017 Aug 17.

7.

Virally vectored vaccine delivery: medical needs, mechanisms, advantages and challenges.

Pinschewer DD.

Swiss Med Wkly. 2017 Aug 8;147:w14465. doi: 10.4414/smw.2017.14465. eCollection 2017. Review.

8.

Recombinant LCMV Vectors Induce Protective Immunity following Homologous and Heterologous Vaccinations.

Wingerath J, Ostroumov D, Woller N, Manns MP, Pinschewer DD, Orlinger K, Berka U, Kühnel F, Wirth TC.

Mol Ther. 2017 Nov 1;25(11):2533-2545. doi: 10.1016/j.ymthe.2017.07.012. Epub 2017 Jul 20.

9.

Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization.

Zeltina A, Krumm SA, Sahin M, Struwe WB, Harlos K, Nunberg JH, Crispin M, Pinschewer DD, Doores KJ, Bowden TA.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7031-7036. doi: 10.1073/pnas.1702127114. Epub 2017 Jun 19.

10.

Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.

Kallert SM, Darbre S, Bonilla WV, Kreutzfeldt M, Page N, Müller P, Kreuzaler M, Lu M, Favre S, Kreppel F, Löhning M, Luther SA, Zippelius A, Merkler D, Pinschewer DD.

Nat Commun. 2017 May 26;8:15327. doi: 10.1038/ncomms15327.

11.

Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens.

Penaloza MacMaster P, Shields JL, Alayo QA, Cabral C, Jimenez J, Mondesir J, Chandrashekar A, Cabral JM, Lim M, Iampietro MJ, Provine NM, Bricault CA, Seaman M, Orlinger K, Aspoeck A, Fuhrmann G, Lilja AE, Monath T, Mangeat B, Pinschewer DD, Barouch DH.

Vaccine. 2017 Jan 3;35(1):1-9. doi: 10.1016/j.vaccine.2016.11.063. Epub 2016 Nov 26.

12.

Interferon-driven deletion of antiviral B cells at the onset of chronic infection.

Fallet B, Narr K, Ertuna YI, Remy M, Sommerstein R, Cornille K, Kreutzfeldt M, Page N, Zimmer G, Geier F, Straub T, Pircher H, Larimore K, Greenberg PD, Merkler D, Pinschewer DD.

Sci Immunol. 2016 Oct 21;1(4). pii: eaah6817. doi: 10.1126/sciimmunol.aah6817.

13.

Additive Protection against Congenital Cytomegalovirus Conferred by Combined Glycoprotein B/pp65 Vaccination Using a Lymphocytic Choriomeningitis Virus Vector.

Schleiss MR, Berka U, Watson E, Aistleithner M, Kiefmann B, Mangeat B, Swanson EC, Gillis PA, Hernandez-Alvarado N, Fernández-Alarcón C, Zabeli JC, Pinschewer DD, Lilja AE, Schwendinger M, Guirakhoo F, Monath TP, Orlinger KK.

Clin Vaccine Immunol. 2017 Jan 5;24(1). pii: e00300-16. doi: 10.1128/CVI.00300-16. Print 2017 Jan.

14.

High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival.

Utzschneider DT, Alfei F, Roelli P, Barras D, Chennupati V, Darbre S, Delorenzi M, Pinschewer DD, Zehn D.

J Exp Med. 2016 Aug 22;213(9):1819-34. doi: 10.1084/jem.20150598. Epub 2016 Jul 25.

15.

Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection.

Sommerstein R, Flatz L, Remy MM, Malinge P, Magistrelli G, Fischer N, Sahin M, Bergthaler A, Igonet S, Ter Meulen J, Rigo D, Meda P, Rabah N, Coutard B, Bowden TA, Lambert PH, Siegrist CA, Pinschewer DD.

PLoS Pathog. 2015 Nov 20;11(11):e1005276. doi: 10.1371/journal.ppat.1005276. eCollection 2015 Nov.

16.

The Nucleoprotein Is Required for Lymphocytic Choriomeningitis Virus-Based Vaccine Vector Immunogenicity.

Darbre S, Johnson S, Kallert S, Lambert PH, Siegrist CA, Pinschewer DD.

J Virol. 2015 Nov;89(22):11734-8. doi: 10.1128/JVI.01613-15. Epub 2015 Sep 9.

17.

T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses.

Baumann C, Bonilla WV, Fröhlich A, Helmstetter C, Peine M, Hegazy AN, Pinschewer DD, Löhning M.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4056-61. doi: 10.1073/pnas.1418549112. Epub 2015 Mar 17.

18.

Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection.

Penaloza-MacMaster P, Barber DL, Wherry EJ, Provine NM, Teigler JE, Parenteau L, Blackmore S, Borducchi EN, Larocca RA, Yates KB, Shen H, Haining WN, Sommerstein R, Pinschewer DD, Ahmed R, Barouch DH.

Science. 2015 Jan 16;347(6219):278-82. doi: 10.1126/science.aaa2148.

19.

Protective efficacy of individual CD8+ T cell specificities in chronic viral infection.

Johnson S, Bergthaler A, Graw F, Flatz L, Bonilla WV, Siegrist CA, Lambert PH, Regoes RR, Pinschewer DD.

J Immunol. 2015 Feb 15;194(4):1755-62. doi: 10.4049/jimmunol.1401771. Epub 2015 Jan 7.

20.

Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses.

Fasnacht N, Huang HY, Koch U, Favre S, Auderset F, Chai Q, Onder L, Kallert S, Pinschewer DD, MacDonald HR, Tacchini-Cottier F, Ludewig B, Luther SA, Radtke F.

J Exp Med. 2014 Oct 20;211(11):2265-79. doi: 10.1084/jem.20132528. Epub 2014 Oct 13.

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