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Items: 1 to 20 of 112

1.

Activation of Siglec-7 results in inhibition of in vitro and in vivo growth of human mast cell leukemia cells.

Landolina N, Zaffran I, Smiljkovic D, Serrano-Candelas E, Schmiedel D, Friedman S, Arock M, Hartmann K, Pikarsky E, Mandelboim O, Martin M, Valent P, Levi-Schaffer F.

Pharmacol Res. 2020 Feb 5:104682. doi: 10.1016/j.phrs.2020.104682. [Epub ahead of print]

PMID:
32035162
2.

The microbiota programs DNA methylation to control intestinal homeostasis and inflammation.

Ansari I, Raddatz G, Gutekunst J, Ridnik M, Cohen D, Abu-Remaileh M, Tuganbaev T, Shapiro H, Pikarsky E, Elinav E, Lyko F, Bergman Y.

Nat Microbiol. 2020 Apr;5(4):610-619. doi: 10.1038/s41564-019-0659-3. Epub 2020 Feb 3.

PMID:
32015497
3.

Are we ready for targeted therapy combinations in HCC?

Cinnamon E, Pikarsky E.

Gut. 2020 Apr;69(4):613-614. doi: 10.1136/gutjnl-2019-319780. Epub 2020 Jan 8. No abstract available.

PMID:
31915236
4.

UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma.

Wolf Y, Bartok O, Patkar S, Eli GB, Cohen S, Litchfield K, Levy R, Jiménez-Sánchez A, Trabish S, Lee JS, Karathia H, Barnea E, Day CP, Cinnamon E, Stein I, Solomon A, Bitton L, Pérez-Guijarro E, Dubovik T, Shen-Orr SS, Miller ML, Merlino G, Levin Y, Pikarsky E, Eisenbach L, Admon A, Swanton C, Ruppin E, Samuels Y.

Cell. 2019 Sep 19;179(1):219-235.e21. doi: 10.1016/j.cell.2019.08.032. Epub 2019 Sep 12.

5.

Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2.

Malakar P, Stein I, Saragovi A, Winkler R, Stern-Ginossar N, Berger M, Pikarsky E, Karni R.

Cancer Res. 2019 May 15;79(10):2480-2493. doi: 10.1158/0008-5472.CAN-18-1432. Epub 2019 Mar 26.

PMID:
30914432
6.

VICKZ1 enhances tumor progression and metastasis in lung adenocarcinomas in mice.

Rosenfeld YB, Krumbein M, Yeffet A, Schiffmann N, Mishalian I, Pikarsky E, Oberman F, Fridlender Z, Yisraeli JK.

Oncogene. 2019 May;38(21):4169-4181. doi: 10.1038/s41388-019-0715-8. Epub 2019 Jan 30.

PMID:
30700831
7.

Author Correction: WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.

Abu-Remaileh M, Khalaileh A, Pikarsky E, Aqeilan RI.

Cell Death Dis. 2018 Nov 23;9(12):1159. doi: 10.1038/s41419-018-1158-9.

8.

Vav1 mutations identified in human cancers give rise to different oncogenic phenotypes.

Shalom B, Farago M, Pikarsky E, Katzav S.

Oncogenesis. 2018 Oct 8;7(10):80. doi: 10.1038/s41389-018-0091-1.

9.

Neighbourhood deaths cause a switch in cancer subtype.

Pikarsky E.

Nature. 2018 Oct;562(7725):45-46. doi: 10.1038/d41586-018-06217-3. No abstract available.

PMID:
30275548
10.

microRNA 193a-5p Regulates Levels of Nucleolar- and Spindle-Associated Protein 1 to Suppress Hepatocarcinogenesis.

Roy S, Hooiveld GJ, Seehawer M, Caruso S, Heinzmann F, Schneider AT, Frank AK, Cardenas DV, Sonntag R, Luedde M, Trautwein C, Stein I, Pikarsky E, Loosen S, Tacke F, Ringelhan M, Avsaroglu SK, Goga A, Buendia MA, Vucur M, Heikenwalder M, Zucman-Rossi J, Zender L, Roderburg C, Luedde T.

Gastroenterology. 2018 Dec;155(6):1951-1966.e26. doi: 10.1053/j.gastro.2018.08.032. Epub 2018 Aug 27.

11.

Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.

Minzel W, Venkatachalam A, Fink A, Hung E, Brachya G, Burstain I, Shaham M, Rivlin A, Omer I, Zinger A, Elias S, Winter E, Erdman PE, Sullivan RW, Fung L, Mercurio F, Li D, Vacca J, Kaushansky N, Shlush L, Oren M, Levine R, Pikarsky E, Snir-Alkalay I, Ben-Neriah Y.

Cell. 2018 Sep 20;175(1):171-185.e25. doi: 10.1016/j.cell.2018.07.045. Epub 2018 Aug 23.

12.

Postnatal DNA demethylation and its role in tissue maturation.

Reizel Y, Sabag O, Skversky Y, Spiro A, Steinberg B, Bernstein D, Wang A, Kieckhaefer J, Li C, Pikarsky E, Levin-Klein R, Goren A, Rajewsky K, Kaestner KH, Cedar H.

Nat Commun. 2018 May 23;9(1):2040. doi: 10.1038/s41467-018-04456-6.

13.

WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.

Abu-Remaileh M, Khalaileh A, Pikarsky E, Aqeilan RI.

Cell Death Dis. 2018 May 1;9(5):511. doi: 10.1038/s41419-018-0510-4. Erratum in: Cell Death Dis. 2018 Nov 23;9(12):1159.

14.

Ev vivo organ culture as potential prioritization tool for breast cancer targeted therapy.

Grinshpun A, Gavert N, Granit RZ, Masuri H, Ben-Porath I, Breuer S, Zick A, Rosenberg S, Maoz M, Granit A, Pikarsky E, Strausmman R, Peretz T, Sonnenblick A.

Cancer Biol Ther. 2018 Aug 3;19(8):645-648. doi: 10.1080/15384047.2018.1450114. Epub 2018 Apr 13.

15.

SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors.

Roth L, Srivastava S, Lindzen M, Sas-Chen A, Sheffer M, Lauriola M, Enuka Y, Noronha A, Mancini M, Lavi S, Tarcic G, Pines G, Nevo N, Heyman O, Ziv T, Rueda OM, Gnocchi D, Pikarsky E, Admon A, Caldas C, Yarden Y.

Sci Signal. 2018 Jan 30;11(515). pii: eaan0949. doi: 10.1126/scisignal.aan0949.

PMID:
29382783
16.

The immunology of hepatocellular carcinoma.

Ringelhan M, Pfister D, O'Connor T, Pikarsky E, Heikenwalder M.

Nat Immunol. 2018 Mar;19(3):222-232. doi: 10.1038/s41590-018-0044-z. Epub 2018 Jan 29. Review.

PMID:
29379119
17.

Learning the Roles of the Hepatic Adaptive Immune System in Hepatocellular Carcinoma-Nature's Guide for Successful Cancer Immunotherapy.

Heikenwälder M, Pikarsky E.

Semin Liver Dis. 2017 Aug;37(3):210-218. doi: 10.1055/s-0037-1606255. Epub 2017 Aug 28. Review. No abstract available.

PMID:
28847032
18.

Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.

Yuan D, Huang S, Berger E, Liu L, Gross N, Heinzmann F, Ringelhan M, Connor TO, Stadler M, Meister M, Weber J, Öllinger R, Simonavicius N, Reisinger F, Hartmann D, Meyer R, Reich M, Seehawer M, Leone V, Höchst B, Wohlleber D, Jörs S, Prinz M, Spalding D, Protzer U, Luedde T, Terracciano L, Matter M, Longerich T, Knolle P, Ried T, Keitel V, Geisler F, Unger K, Cinnamon E, Pikarsky E, Hüser N, Davis RJ, Tschaharganeh DF, Rad R, Weber A, Zender L, Haller D, Heikenwalder M.

Cancer Cell. 2017 Jun 12;31(6):771-789.e6. doi: 10.1016/j.ccell.2017.05.006.

19.

Treatment inferred from mutations identified using massive parallel sequencing leads to clinical benefit in some heavily pretreated cancer patients.

Zick A, Peretz T, Lotem M, Hubert A, Katz D, Temper M, Rottenberg Y, Uziely B, Nechushtan H, Meirovitz A, Sonnenblick A, Sapir E, Edelman D, Goldberg Y, Lossos A, Rosenberg S, Fried I, Finklstein R, Pikarsky E, Goldshmidt H.

Medicine (Baltimore). 2017 May;96(20):e6931. doi: 10.1097/MD.0000000000006931.

20.

miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression.

Hanin G, Yayon N, Tzur Y, Haviv R, Bennett ER, Udi S, Krishnamoorthy YR, Kotsiliti E, Zangen R, Efron B, Tam J, Pappo O, Shteyer E, Pikarsky E, Heikenwalder M, Greenberg DS, Soreq H.

Gut. 2018 Jun;67(6):1124-1134. doi: 10.1136/gutjnl-2016-312869. Epub 2017 Apr 5.

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