Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 39

1.

Analyzing biased responses of GPCR ligands.

Benredjem B, Dallaire P, Pineyro G.

Curr Opin Pharmacol. 2017 Feb;32:71-76. doi: 10.1016/j.coph.2016.11.008. Epub 2016 Dec 6. Review.

PMID:
27930943
2.

Molecular Pharmacology of δ-Opioid Receptors.

Gendron L, Cahill CM, von Zastrow M, Schiller PW, Pineyro G.

Pharmacol Rev. 2016 Jul;68(3):631-700. doi: 10.1124/pr.114.008979. Review.

3.

Practical guide for calculating and representing biased signaling by GPCR ligands: A stepwise approach.

Nagi K, Pineyro G.

Methods. 2016 Jan 1;92:78-86. doi: 10.1016/j.ymeth.2015.09.010. Epub 2015 Sep 11. Review.

PMID:
26364590
4.

Design and construction of conformational biosensors to monitor ion channel activation: A prototype FlAsH/BRET-approach to Kir3 channels.

Robertson DN, Sleno R, Nagi K, Pétrin D, Hébert TE, Pineyro G.

Methods. 2016 Jan 1;92:19-35. doi: 10.1016/j.ymeth.2015.07.011. Epub 2015 Jul 22.

PMID:
26210401
5.

Kir3 channels undergo arrestin-dependant internalization following delta opioid receptor activation.

Nagi K, Charfi I, Pineyro G.

Cell Mol Life Sci. 2015 Sep;72(18):3543-57. doi: 10.1007/s00018-015-1899-x. Epub 2015 Apr 22.

PMID:
25900661
6.

Kir3 channel signaling complexes: focus on opioid receptor signaling.

Nagi K, Pineyro G.

Front Cell Neurosci. 2014 Jul 8;8:186. doi: 10.3389/fncel.2014.00186. eCollection 2014. Review.

7.

Label-free monitoring of μ-opioid receptor-mediated signaling.

Bourassa P, Tudashki HB, Pineyro G, Grandbois M, Gendron L.

Mol Pharmacol. 2014 Aug;86(2):138-49. doi: 10.1124/mol.114.093450. Epub 2014 May 29.

8.

Identifying ligand-specific signalling within biased responses: focus on δ opioid receptor ligands.

Charfi I, Audet N, Bagheri Tudashki H, Pineyro G.

Br J Pharmacol. 2015 Jan;172(2):435-48. doi: 10.1111/bph.12705. Epub 2014 Jul 1. Review.

9.

Endocytic profiles of δ-opioid receptor ligands determine the duration of rapid but not sustained cAMP responses.

Tudashki HB, Robertson DN, Schiller PW, Pineyro G.

Mol Pharmacol. 2014 Jan;85(1):148-61. doi: 10.1124/mol.113.089003. Epub 2013 Oct 30.

10.

Ligand- and cell-dependent determinants of internalization and cAMP modulation by delta opioid receptor (DOR) agonists.

Charfi I, Nagi K, Mnie-Filali O, Thibault D, Balboni G, Schiller PW, Trudeau LE, Pineyro G.

Cell Mol Life Sci. 2014 Apr;71(8):1529-46.

11.

Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.

Richard-Lalonde M, Nagi K, Audet N, Sleno R, Amraei M, Hogue M, Balboni G, Schiller PW, Bouvier M, Hébert TE, Pineyro G.

Mol Pharmacol. 2013 Feb;83(2):416-28. doi: 10.1124/mol.112.081950. Epub 2012 Nov 21.

12.

Differential association of receptor-Gβγ complexes with β-arrestin2 determines recycling bias and potential for tolerance of δ opioid receptor agonists.

Audet N, Charfi I, Mnie-Filali O, Amraei M, Chabot-Doré AJ, Millecamps M, Stone LS, Pineyro G.

J Neurosci. 2012 Apr 4;32(14):4827-40. doi: 10.1523/JNEUROSCI.3734-11.2012.

13.

Using BRET to detect ligand-specific conformational changes in preformed signalling complexes.

Audet N, Piñeyro G.

Methods Mol Biol. 2011;756:149-63. doi: 10.1007/978-1-61779-160-4_7.

PMID:
21870224
14.

Regulation of opioid receptor signalling: implications for the development of analgesic tolerance.

Nagi K, Piñeyro G.

Mol Brain. 2011 Jun 13;4:25. doi: 10.1186/1756-6606-4-25. Review.

15.

Neurotensin triggers dopamine D2 receptor desensitization through a protein kinase C and beta-arrestin1-dependent mechanism.

Thibault D, Albert PR, Pineyro G, Trudeau LÉ.

J Biol Chem. 2011 Mar 18;286(11):9174-84. doi: 10.1074/jbc.M110.166454. Epub 2011 Jan 13.

16.

Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat.

Lucas G, Du J, Romeas T, Mnie-Filali O, Haddjeri N, Piñeyro G, Debonnel G.

PLoS One. 2010 Feb 16;5(2):e9253. doi: 10.1371/journal.pone.0009253.

17.

Serotonin 4 receptor (5-HT4R) internalization is isoform-specific: effects of 5-HT and RS67333 on isoforms A and B.

Mnie-Filali O, Amraei MG, Benmbarek S, Archer-Lahlou E, Peñas-Cazorla R, Vilaró MT, Boye SM, Piñeyro G.

Cell Signal. 2010 Mar;22(3):501-9. doi: 10.1016/j.cellsig.2009.11.004.

PMID:
19922792
18.

Simultaneous anhedonia and exaggerated locomotor activation in an animal model of depression.

Romeas T, Morissette MC, Mnie-Filali O, Piñeyro G, Boye SM.

Psychopharmacology (Berl). 2009 Aug;205(2):293-303. doi: 10.1007/s00213-009-1539-y. Epub 2009 Apr 29.

PMID:
19404615
19.

Membrane signalling complexes: implications for development of functionally selective ligands modulating heptahelical receptor signalling.

Piñeyro G.

Cell Signal. 2009 Feb;21(2):179-85. doi: 10.1016/j.cellsig.2008.08.013. Epub 2008 Aug 28. Review.

PMID:
18790047
20.

Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.

Audet N, Galés C, Archer-Lahlou E, Vallières M, Schiller PW, Bouvier M, Pineyro G.

J Biol Chem. 2008 May 30;283(22):15078-88. doi: 10.1074/jbc.M707941200. Epub 2008 Apr 1.

Supplemental Content

Loading ...
Support Center