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Items: 1 to 20 of 219


Heterogeneity in gut microbiota drive polyphenol metabolism that influences α-synuclein misfolding and toxicity.

Ho L, Zhao D, Ono K, Ruan K, Mogno I, Tsuji M, Carry E, Brathwaite J, Sims S, Frolinger T, Westfall S, Mazzola P, Wu Q, Hao K, Lloyd TE, Simon JE, Faith J, Pasinetti GM.

J Nutr Biochem. 2018 Nov 14;64:170-181. doi: 10.1016/j.jnutbio.2018.10.019. [Epub ahead of print]


Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations.

Smith C, Frolinger T, Brathwaite J, Sims S, Pasinetti GM.

Commun Biol. 2018 May 3;1:42. doi: 10.1038/s42003-018-0043-5. eCollection 2018.


Development and validation of an ultra-high performance liquid chromatography/triple quadrupole mass spectrometry method for analyzing microbial-derived grape polyphenol metabolites.

Zhao D, Yuan B, Carry E, Pasinetti GM, Ho L, Faith J, Mogno I, Simon J, Wu Q.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Nov 1;1099:34-45. doi: 10.1016/j.jchromb.2018.09.014. Epub 2018 Sep 12.


Suppression of Presymptomatic Oxidative Stress and Inflammation in Neurodegeneration by Grape-Derived Polyphenols.

Herman F, Westfall S, Brathwaite J, Pasinetti GM.

Front Pharmacol. 2018 Aug 28;9:867. doi: 10.3389/fphar.2018.00867. eCollection 2018. Review.


Targeted analysis of microbial-generated phenolic acid metabolites derived from grape flavanols by gas chromatography-triple quadrupole mass spectrometry.

Carry E, Zhao D, Mogno I, Faith J, Ho L, Villani T, Patel H, Pasinetti GM, Simon JE, Wu Q.

J Pharm Biomed Anal. 2018 Sep 10;159:374-383. doi: 10.1016/j.jpba.2018.06.034. Epub 2018 Jun 20.


Epigenetic modifications by polyphenolic compounds alter gene expression in the hippocampus.

Frolinger T, Herman F, Sharma A, Sims S, Wang J, Pasinetti GM.

Biol Open. 2018 Oct 4;7(10). pii: bio035196. doi: 10.1242/bio.035196.


Principles of inflammasome priming and inhibition: Implications for psychiatric disorders.

Herman FJ, Pasinetti GM.

Brain Behav Immun. 2018 Oct;73:66-84. doi: 10.1016/j.bbi.2018.06.010. Epub 2018 Jun 11. Review.


Prevalence of dry eye in video display terminal users: a cross-sectional Caucasian study in Italy.

Rossi GCM, Scudeller L, Bettio F, Pasinetti GM, Bianchi PE.

Int Ophthalmol. 2018 Jun 7. doi: 10.1007/s10792-018-0947-6. [Epub ahead of print]


An Extract of Artemisia dracunculus L. Promotes Psychological Resilience in a Mouse Model of Depression.

Wang J, Fernández AE, Tiano S, Huang J, Floyd E, Poulev A, Ribnicky D, Pasinetti GM.

Oxid Med Cell Longev. 2018 May 13;2018:7418681. doi: 10.1155/2018/7418681. eCollection 2018.


Dietary polyphenols promote resilience against sleep deprivation-induced cognitive impairment by activating protein translation.

Frolinger T, Smith C, Cobo CF, Sims S, Brathwaite J, de Boer S, Huang J, Pasinetti GM.

FASEB J. 2018 Oct;32(10):5390-5404. doi: 10.1096/fj.201800030R. Epub 2018 Apr 27.


The Role of the Gut Microbiota in the Metabolism of Polyphenols as Characterized by Gnotobiotic Mice.

Pasinetti GM, Singh R, Westfall S, Herman F, Faith J, Ho L.

J Alzheimers Dis. 2018;63(2):409-421. doi: 10.3233/JAD-171151.


Endoscopic retrograde cholangiopancreatography in the elderly: results of a retrospective study and a geriatricians' point of view.

Galeazzi M, Mazzola P, Valcarcel B, Bellelli G, Dinelli M, Pasinetti GM, Annoni G.

BMC Gastroenterol. 2018 Mar 14;18(1):38. doi: 10.1186/s12876-018-0764-4.


Polyphenolic Compounds Alter Stress-Induced Patterns of Global DNA Methylation in Brain and Blood.

Blaze J, Wang J, Ho L, Mendelev N, Haghighi F, Pasinetti GM.

Mol Nutr Food Res. 2018 Apr;62(8):e1700722. doi: 10.1002/mnfr.201700722. Epub 2018 Mar 22.


Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice.

Wang J, Hodes GE, Zhang H, Zhang S, Zhao W, Golden SA, Bi W, Menard C, Kana V, Leboeuf M, Xie M, Bregman D, Pfau ML, Flanigan ME, Esteban-Fernández A, Yemul S, Sharma A, Ho L, Dixon R, Merad M, Han MH, Russo SJ, Pasinetti GM.

Nat Commun. 2018 Feb 2;9(1):477. doi: 10.1038/s41467-017-02794-5.


Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer's disease-type beta-amyloid neuropathological mechanisms.

Ho L, Ono K, Tsuji M, Mazzola P, Singh R, Pasinetti GM.

Expert Rev Neurother. 2018 Jan;18(1):83-90. doi: 10.1080/14737175.2018.1400909. Epub 2017 Nov 14.


A Comprehensive Database and Analysis Framework To Incorporate Multiscale Data Types and Enable Integrated Analysis of Bioactive Polyphenols.

Ho L, Cheng H, Wang J, Simon JE, Wu Q, Zhao D, Carry E, Ferruzzi MG, Faith J, Valcarcel B, Hao K, Pasinetti GM.

Mol Pharm. 2018 Mar 5;15(3):840-850. doi: 10.1021/acs.molpharmaceut.7b00412. Epub 2018 Feb 5.


The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans.

Novotny JA, Chen TY, Terekhov AI, Gebauer SK, Baer DJ, Ho L, Pasinetti GM, Ferruzzi MG.

Mol Nutr Food Res. 2017 Nov;61(11). doi: 10.1002/mnfr.201700043. Epub 2017 Aug 29.


Influence of diabetes on plasma pharmacokinetics and brain bioavailability of grape polyphenols and their phase II metabolites in the Zucker diabetic fatty rat.

Chen TY, Ferruzzi MG, Wu QL, Simon JE, Talcott ST, Wang J, Ho L, Todd G, Cooper B, Pasinetti GM, Janle EM.

Mol Nutr Food Res. 2017 Oct;61(10). doi: 10.1002/mnfr.201700111. Epub 2017 Aug 14.


Association Between Preoperative Malnutrition and Postoperative Delirium After Hip Fracture Surgery in Older Adults.

Mazzola P, Ward L, Zazzetta S, Broggini V, Anzuini A, Valcarcel B, Brathwaite JS, Pasinetti GM, Bellelli G, Annoni G.

J Am Geriatr Soc. 2017 Jun;65(6):1222-1228. doi: 10.1111/jgs.14764. Epub 2017 Mar 6.


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