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Items: 10

1.

Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus.

Angelova M, Ortiz-Meoz RF, Walker S, Knipe DM.

J Virol. 2015 Aug;89(16):8474-83. doi: 10.1128/JVI.01002-15. Epub 2015 Jun 3.

2.

A small molecule that inhibits OGT activity in cells.

Ortiz-Meoz RF, Jiang J, Lazarus MB, Orman M, Janetzko J, Fan C, Duveau DY, Tan ZW, Thomas CJ, Walker S.

ACS Chem Biol. 2015 Jun 19;10(6):1392-7. doi: 10.1021/acschembio.5b00004. Epub 2015 Mar 18.

3.

Microarray discovery of new OGT substrates: the medulloblastoma oncogene OTX2 is O-GlcNAcylated.

Ortiz-Meoz RF, Merbl Y, Kirschner MW, Walker S.

J Am Chem Soc. 2014 Apr 2;136(13):4845-8. doi: 10.1021/ja500451w. Epub 2014 Mar 17.

4.

Structural characterization of mRNA-tRNA translocation intermediates.

Agirrezabala X, Liao HY, Schreiner E, Fu J, Ortiz-Meoz RF, Schulten K, Green R, Frank J.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6094-9. doi: 10.1073/pnas.1201288109. Epub 2012 Mar 30.

5.

Helix 69 is key for uniformity during substrate selection on the ribosome.

Ortiz-Meoz RF, Green R.

J Biol Chem. 2011 Jul 22;286(29):25604-10. doi: 10.1074/jbc.M111.256255. Epub 2011 May 27.

6.

Structural insights into cognate versus near-cognate discrimination during decoding.

Agirrezabala X, Schreiner E, Trabuco LG, Lei J, Ortiz-Meoz RF, Schulten K, Green R, Frank J.

EMBO J. 2011 Apr 20;30(8):1497-507. doi: 10.1038/emboj.2011.58. Epub 2011 Mar 4.

7.

Functional elucidation of a key contact between tRNA and the large ribosomal subunit rRNA during decoding.

Ortiz-Meoz RF, Green R.

RNA. 2010 Oct;16(10):2002-13. doi: 10.1261/rna.2232710. Epub 2010 Aug 25.

8.

Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM.

Li W, Agirrezabala X, Lei J, Bouakaz L, Brunelle JL, Ortiz-Meoz RF, Green R, Sanyal S, Ehrenberg M, Frank J.

EMBO J. 2008 Dec 17;27(24):3322-31. doi: 10.1038/emboj.2008.243. Epub 2008 Nov 20.

9.

Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome.

Agirrezabala X, Lei J, Brunelle JL, Ortiz-Meoz RF, Green R, Frank J.

Mol Cell. 2008 Oct 24;32(2):190-7. doi: 10.1016/j.molcel.2008.10.001.

10.

Photosensitized DNA cleavage promoted by amino acids.

Mahon KP Jr, Ortiz-Meoz RF, Prestwich EG, Kelley SO.

Chem Commun (Camb). 2003 Aug 7;(15):1956-7.

PMID:
12932051

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