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The first international mini-symposium on methionine restriction and lifespan.

Ables GP, Brown-Borg HM, Buffenstein R, Church CD, Elshorbagy AK, Gladyshev VN, Huang TH, Miller RA, Mitchell JR, Richie JP, Rogina B, Stipanuk MH, Orentreich DS, Orentreich N.

Front Genet. 2014 May 9;5:122. doi: 10.3389/fgene.2014.00122. eCollection 2014.


Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.


Methionine-restricted C57BL/6J mice are resistant to diet-induced obesity and insulin resistance but have low bone density.

Ables GP, Perrone CE, Orentreich D, Orentreich N.

PLoS One. 2012;7(12):e51357. doi: 10.1371/journal.pone.0051357. Epub 2012 Dec 7. Erratum in: PLoS One. 2014;9(7):e104050.


Effect of taurine and N-acetylcysteine on methionine restriction-mediated adiposity resistance.

Elshorbagy AK, Valdivia-Garcia M, Mattocks DA, Plummer JD, Orentreich DS, Orentreich N, Refsum H, Perrone CE.

Metabolism. 2013 Apr;62(4):509-17. doi: 10.1016/j.metabol.2012.10.005. Epub 2012 Nov 13.


Genomic and metabolic responses to methionine-restricted and methionine-restricted, cysteine-supplemented diets in Fischer 344 rat inguinal adipose tissue, liver and quadriceps muscle.

Perrone CE, Mattocks DA, Plummer JD, Chittur SV, Mohney R, Vignola K, Orentreich DS, Orentreich N.

J Nutrigenet Nutrigenomics. 2012;5(3):132-57. doi: 10.1159/000339347. Epub 2012 Oct 9.


Metabolic adaptations to methionine restriction that benefit health and lifespan in rodents.

Perrone CE, Malloy VL, Orentreich DS, Orentreich N.

Exp Gerontol. 2013 Jul;48(7):654-60. doi: 10.1016/j.exger.2012.07.005. Epub 2012 Jul 20. Review.


Circulating angiopoietins-1 and -2, angiopoietin receptor Tie-2 and vascular endothelial growth factor-A as biomarkers of acute myocardial infarction: a prospective nested case-control study.

Iribarren C, Phelps BH, Darbinian JA, McCluskey ER, Quesenberry CP, Hytopoulos E, Vogelman JH, Orentreich N.

BMC Cardiovasc Disord. 2011 Jun 14;11:31. doi: 10.1186/1471-2261-11-31.


Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome.

Plaisance EP, Greenway FL, Boudreau A, Hill KL, Johnson WD, Krajcik RA, Perrone CE, Orentreich N, Cefalu WT, Gettys TW.

J Clin Endocrinol Metab. 2011 May;96(5):E836-40. doi: 10.1210/jc.2010-2493. Epub 2011 Feb 23.


Role of beta-adrenergic receptors in the hyperphagic and hypermetabolic responses to dietary methionine restriction.

Plaisance EP, Henagan TM, Echlin H, Boudreau A, Hill KL, Lenard NR, Hasek BE, Orentreich N, Gettys TW.

Am J Physiol Regul Integr Comp Physiol. 2010 Sep;299(3):R740-50. doi: 10.1152/ajpregu.00838.2009. Epub 2010 Jun 16.


Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states.

Hasek BE, Stewart LK, Henagan TM, Boudreau A, Lenard NR, Black C, Shin J, Huypens P, Malloy VL, Plaisance EP, Krajcik RA, Orentreich N, Gettys TW.

Am J Physiol Regul Integr Comp Physiol. 2010 Sep;299(3):R728-39. doi: 10.1152/ajpregu.00837.2009. Epub 2010 Jun 10.


Methionine restriction effects on mitochondrial biogenesis and aerobic capacity in white adipose tissue, liver, and skeletal muscle of F344 rats.

Perrone CE, Mattocks DA, Jarvis-Morar M, Plummer JD, Orentreich N.

Metabolism. 2010 Jul;59(7):1000-11. doi: 10.1016/j.metabol.2009.10.023. Epub 2010 Jan 4. Erratum in: Metabolism. 2010 Nov;59(11):e20.


Association of prediagnostic serum vitamin D levels with the development of basal cell carcinoma.

Asgari MM, Tang J, Warton ME, Chren MM, Quesenberry CP Jr, Bikle D, Horst RL, Orentreich N, Vogelman JH, Friedman GD.

J Invest Dermatol. 2010 May;130(5):1438-43. doi: 10.1038/jid.2009.402. Epub 2009 Dec 31.


Helicobacter pylori infection and development of pancreatic cancer.

de Martel C, Llosa AE, Friedman GD, Vogelman JH, Orentreich N, Stolzenberg-Solomon RZ, Parsonnet J.

Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1188-94. doi: 10.1158/1055-9965.EPI-08-0185. Erratum in: Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2901. Friedmana, Gary D [corrected to Friedman, Gary D].


Methionine restriction effects on 11 -HSD1 activity and lipogenic/lipolytic balance in F344 rat adipose tissue.

Perrone CE, Mattocks DA, Hristopoulos G, Plummer JD, Krajcik RA, Orentreich N.

J Lipid Res. 2008 Jan;49(1):12-23. Epub 2007 Oct 1.


Serum ghrelin levels and risk of subsequent adenocarcinoma of the esophagus.

de Martel C, Haggerty TD, Corley DA, Vogelman JH, Orentreich N, Parsonnet J.

Am J Gastroenterol. 2007 Jun;102(6):1166-72. Epub 2007 Mar 22.


Infections and "unrelated" diseases.

Orentreich N.

Hawaii Med J. 2006 Nov;65(11):308-9. No abstract available.


Methionine restriction decreases visceral fat mass and preserves insulin action in aging male Fischer 344 rats independent of energy restriction.

Malloy VL, Krajcik RA, Bailey SJ, Hristopoulos G, Plummer JD, Orentreich N.

Aging Cell. 2006 Aug;5(4):305-14. Epub 2006 Jun 26.


Does the association between serum endostatin, an endogenous anti-angiogenic protein, and acute myocardial infarction differ by race?

Iribarren C, Herrinton LJ, Darbinian JA, Tamarkin L, Malinowski D, Vogelman JH, Orentreich N, Baer D.

Vasc Med. 2006 Feb;11(1):13-20.


Epstein-Barr virus and multiple sclerosis: evidence of association from a prospective study with long-term follow-up.

DeLorenze GN, Munger KL, Lennette ET, Orentreich N, Vogelman JH, Ascherio A.

Arch Neurol. 2006 Jun;63(6):839-44. Epub 2006 Apr 10.


Helicobacter pylori infection and the risk of development of esophageal adenocarcinoma.

de Martel C, Llosa AE, Farr SM, Friedman GD, Vogelman JH, Orentreich N, Corley DA, Parsonnet J.

J Infect Dis. 2005 Mar 1;191(5):761-7. Epub 2005 Jan 20.


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